Sijbren Kramer
@sijbren-kramer.bsky.social
Reposted by Sijbren Kramer
Avian flu threatens global health and agriculture, with pandemic potential☣️ if it spreads between humans😷. To enable surveillance, we developed 3 CRISPR-based assays for rapid subtype- and clade-specific detection of avian influenza in low-resource settings.⬇️ (1/11)
www.medrxiv.org/content/10.1...
www.medrxiv.org/content/10.1...
Streamlined CRISPR-based assays for detection and subtyping of avian influenza
Avian influenza viruses (AIVs) are zoonotic pathogens that pose an increasing global threat due to their potential for human-to-human transmission, pandemic emergence and significant economic losses i...
www.medrxiv.org
August 27, 2025 at 7:01 PM
Avian flu threatens global health and agriculture, with pandemic potential☣️ if it spreads between humans😷. To enable surveillance, we developed 3 CRISPR-based assays for rapid subtype- and clade-specific detection of avian influenza in low-resource settings.⬇️ (1/11)
www.medrxiv.org/content/10.1...
www.medrxiv.org/content/10.1...
Multiplexed nucleic acid detection is critical for the surveillance of pathogens and mutations, but existing technologies either require extensive lab equipment or have low multiplexing. We built a portable microfluidic manifold for massively multiplexed CRISPR-based detection. (1/12)
A handheld microfluidic manifold for massively multiplexed CRISPR-based nucleic acid detection
Multiplexed methods for nucleic acid detection are immensely challenging to deploy outside of laboratory settings. Conversely, field-deployable methods are limited to low levels of multiplexing. Durin...
www.biorxiv.org
August 15, 2025 at 6:34 PM
Multiplexed nucleic acid detection is critical for the surveillance of pathogens and mutations, but existing technologies either require extensive lab equipment or have low multiplexing. We built a portable microfluidic manifold for massively multiplexed CRISPR-based detection. (1/12)