@yujiah.bsky.social
Reposted
Despite antibiotic treatments, tuberculosis (TB) remains an enormous global health burden, in part driven by the difficulties in timely and accurate diagnosis. Can we use CRISPR to improve TB diagnosis to make it faster, simpler, and more accessible? (1/21)
August 7, 2025 at 3:29 PM
Despite antibiotic treatments, tuberculosis (TB) remains an enormous global health burden, in part driven by the difficulties in timely and accurate diagnosis. Can we use CRISPR to improve TB diagnosis to make it faster, simpler, and more accessible? (1/21)
Reposted
Multiplexed nucleic acid detection is critical for the surveillance of pathogens and mutations, but existing technologies either require extensive lab equipment or have low multiplexing. We built a portable microfluidic manifold for massively multiplexed CRISPR-based detection. (1/12)
A handheld microfluidic manifold for massively multiplexed CRISPR-based nucleic acid detection
Multiplexed methods for nucleic acid detection are immensely challenging to deploy outside of laboratory settings. Conversely, field-deployable methods are limited to low levels of multiplexing. Durin...
www.biorxiv.org
August 15, 2025 at 6:34 PM
Multiplexed nucleic acid detection is critical for the surveillance of pathogens and mutations, but existing technologies either require extensive lab equipment or have low multiplexing. We built a portable microfluidic manifold for massively multiplexed CRISPR-based detection. (1/12)
Avian flu threatens global health and agriculture, with pandemic potential☣️ if it spreads between humans😷. To enable surveillance, we developed 3 CRISPR-based assays for rapid subtype- and clade-specific detection of avian influenza in low-resource settings.⬇️ (1/11)
www.medrxiv.org/content/10.1...
www.medrxiv.org/content/10.1...
Streamlined CRISPR-based assays for detection and subtyping of avian influenza
Avian influenza viruses (AIVs) are zoonotic pathogens that pose an increasing global threat due to their potential for human-to-human transmission, pandemic emergence and significant economic losses i...
www.medrxiv.org
August 27, 2025 at 7:01 PM
Avian flu threatens global health and agriculture, with pandemic potential☣️ if it spreads between humans😷. To enable surveillance, we developed 3 CRISPR-based assays for rapid subtype- and clade-specific detection of avian influenza in low-resource settings.⬇️ (1/11)
www.medrxiv.org/content/10.1...
www.medrxiv.org/content/10.1...