Matthew Macauley
@siglecdude.bsky.social
R.U. Lemieux Chair of Carbohydrate Chemistry
Professor, Department of Chemsitry
University of Alberta
Professor, Department of Chemsitry
University of Alberta
The link to our original study seems to be broken, so here it is: www.nature.com/articles/s41...
Siglec-6 mediates the uptake of extracellular vesicles through a noncanonical glycolipid binding pocket - Nature Communications
Siglec-glycolipid interactions are often studied outside the context of a lipid bilayer. Here, the authors combine a variety of chemical biology techniques to demonstrate a unique and physiologically ...
www.nature.com
June 22, 2025 at 12:32 PM
The link to our original study seems to be broken, so here it is: www.nature.com/articles/s41...
I missed Zeinab's handle: @zeinab-jc.bsky.social.
June 15, 2025 at 4:54 PM
I missed Zeinab's handle: @zeinab-jc.bsky.social.
Shoot, I couldn’t find her handle. Now I got it!
June 15, 2025 at 4:36 PM
Shoot, I couldn’t find her handle. Now I got it!
Contributions by various members of my group: Zeinab, Eddie, @m-joe.bsky.social e.bsky.social, Fahim, and Sam.
June 12, 2025 at 1:27 PM
Contributions by various members of my group: Zeinab, Eddie, @m-joe.bsky.social e.bsky.social, Fahim, and Sam.
They are quite comfortable. I wear them all the time. Thanks for coming !
May 30, 2025 at 6:56 PM
They are quite comfortable. I wear them all the time. Thanks for coming !
Sorry to hear. Hope the rest of your trip goes well.
May 27, 2025 at 3:50 PM
Sorry to hear. Hope the rest of your trip goes well.
Ya. We thought about this a lot to be honest and went back and re-made mutants to be sure. Had some very helpful conversations with Adnan.
January 22, 2025 at 4:34 PM
Ya. We thought about this a lot to be honest and went back and re-made mutants to be sure. Had some very helpful conversations with Adnan.
Makes sense. Is cell surface glycomics possible to address this?
November 23, 2024 at 6:18 PM
Makes sense. Is cell surface glycomics possible to address this?
Ha…I had been thinking about the same issues (posted about this in parallel under Carolyn’s post) but now see Anne’s respond below that is a bit reassuring that this is a very rare event (terminal GlcNAc) under normal healthy conditions.
November 22, 2024 at 8:56 PM
Ha…I had been thinking about the same issues (posted about this in parallel under Carolyn’s post) but now see Anne’s respond below that is a bit reassuring that this is a very rare event (terminal GlcNAc) under normal healthy conditions.
Good call on @maxcrispin.bsky.social
November 22, 2024 at 8:50 PM
Good call on @maxcrispin.bsky.social
Indeed, a super intriguing study that I loved reading. Been thinking about this and how rare/'non-self' a terminal GlcNAc is. Hoping to get some input for mass spec community - @cashwood.bsky.social, @nickescott.bsky.social @nmriley.bsky.social @khookh.bsky.social @StacyMalakar (can't your handle)?
November 22, 2024 at 6:45 PM
Indeed, a super intriguing study that I loved reading. Been thinking about this and how rare/'non-self' a terminal GlcNAc is. Hoping to get some input for mass spec community - @cashwood.bsky.social, @nickescott.bsky.social @nmriley.bsky.social @khookh.bsky.social @StacyMalakar (can't your handle)?