Shan Jiang
@shanjiang.bsky.social
DPhil Neuroscience, University of Oxford, spatial navigation, sleep
Pinned
Shan Jiang
@shanjiang.bsky.social
· Nov 28
Pathological tau alters head direction signaling and induces spatial disorientation https://www.biorxiv.org/content/10.1101/2024.11.07.622548v1
Pathological tau alters head direction signaling and induces spatial disorientation https://www.biorxiv.org/content/10.1101/2024.11.07.622548v1
Disorientation is an early symptom of dementia, suggesting impairments in neural circuits responsibl
www.biorxiv.org
First paper from my DPhil research project;)
Reposted by Shan Jiang
Really excited to share this Opinion piece we've been working on with fellow head-direction cell geeks @apeyrache.bsky.social @desdemonafricker.bsky.social and (bsky-less?) Andrea Burgalossi! While head-direction cells pop up in many cortical regions, we think that one of them is quite unique (1/8)
The postsubiculum as a head-direction cortex
The organisation of thalamocortical networks follows a conserved structure. Traditionally, these are divided into primary sensory systems that receive…
www.sciencedirect.com
October 15, 2025 at 8:10 PM
Really excited to share this Opinion piece we've been working on with fellow head-direction cell geeks @apeyrache.bsky.social @desdemonafricker.bsky.social and (bsky-less?) Andrea Burgalossi! While head-direction cells pop up in many cortical regions, we think that one of them is quite unique (1/8)
Reposted by Shan Jiang
*New preprint from the lab* – “Granularity of thalamic head direction cells”
doi.org/10.1101/2025...
🧠📈 🧪
1/11
doi.org/10.1101/2025...
🧠📈 🧪
1/11
Granularity of thalamic head direction cells
Head direction signaling is fundamental for spatial orientation and navigation. The anterodorsal nucleus of the thalamus (ADn) contains a high density of head direction (HD) cells that process sensori...
doi.org
September 15, 2025 at 3:13 PM
*New preprint from the lab* – “Granularity of thalamic head direction cells”
doi.org/10.1101/2025...
🧠📈 🧪
1/11
doi.org/10.1101/2025...
🧠📈 🧪
1/11
First spring hippocampus conference in Verona! Great experience with interesting talks and meeting amazing people there;)
May 23, 2025 at 4:52 PM
First spring hippocampus conference in Verona! Great experience with interesting talks and meeting amazing people there;)
First paper from my DPhil research project;)
Pathological tau alters head direction signaling and induces spatial disorientation https://www.biorxiv.org/content/10.1101/2024.11.07.622548v1
Pathological tau alters head direction signaling and induces spatial disorientation https://www.biorxiv.org/content/10.1101/2024.11.07.622548v1
Disorientation is an early symptom of dementia, suggesting impairments in neural circuits responsibl
www.biorxiv.org
November 28, 2024 at 2:18 PM
First paper from my DPhil research project;)
Reposted by Shan Jiang
Pleased to say our study led by James Street
showing a requirement for the LGN pathway for visual landmark control of head direction cells is now published! physoc.onlinelibrary.wiley.com/doi/10.1113/...
showing a requirement for the LGN pathway for visual landmark control of head direction cells is now published! physoc.onlinelibrary.wiley.com/doi/10.1113/...
The dorsal thalamic lateral geniculate nucleus is required for visual control of head direction cell firing direction in rats
Abstract figure legend Head direction cells in the rodent postsubiculum (PoS) are oriented by environmental visual cues, assessed in the laboratory using a cue-controlled environment. We investigated....
physoc.onlinelibrary.wiley.com
September 6, 2024 at 6:26 AM
Pleased to say our study led by James Street
showing a requirement for the LGN pathway for visual landmark control of head direction cells is now published! physoc.onlinelibrary.wiley.com/doi/10.1113/...
showing a requirement for the LGN pathway for visual landmark control of head direction cells is now published! physoc.onlinelibrary.wiley.com/doi/10.1113/...
Reposted by Shan Jiang
Pleased to share our #neuroscience preprint on how tau pathology affects head direction cells of the anterodorsal thalamus and induces disorientation, an early sign of #dementia
Pathological tau alters head direction signaling and induces spatial disorientation https://www.biorxiv.org/content/10.1101/2024.11.07.622548v1
Pathological tau alters head direction signaling and induces spatial disorientation https://www.biorxiv.org/content/10.1101/2024.11.07.622548v1
Disorientation is an early symptom of dementia, suggesting impairments in neural circuits responsibl
www.biorxiv.org
November 9, 2024 at 3:52 PM
Pleased to share our #neuroscience preprint on how tau pathology affects head direction cells of the anterodorsal thalamus and induces disorientation, an early sign of #dementia