Great observation! Here’s an image from our dataset — the OB has a much higher vessel density than the rest of the brain, suggesting distinct vascular architecture. The video focus was set for brain contrast, causing overexposure in the highly vascular OBs.

3D STED of PSD95-STAR RED, in cleared mouse brain tissue. 50% TauSTED 3D (left) and 100% TauSTED 3D (right), showing the difference in the axial resolution decrease from 274nm (left) to 143nm(right)! Sample prepared by Thomas Stroh group
Montreal Neurological Institute
(MNI). #MLMC 2025-July.