Christopher Seymour
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Christopher Seymour
@seymoc.bsky.social
280 followers 290 following 2 posts
Associate Editor, JAMA, Caring for the Critically ill
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Father, sheep farmer, ICU doctor.
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(Views my own)
Posts Replies Media Videos
Reposted by Christopher Seymour
jama.com
Introducing JAMA’s Research of the Year.

Chosen by JAMA editors, the inaugural roundup highlights 9 of the most impactful, newsworthy, and novel studies published in the journal over the past year. 🧵

#JAMAROTY25

🔗 ja.ma/4pAihne
December 12, 2025 at 4:15 PM
Reposted by Christopher Seymour
jama.com
Amid federal funding cuts- and often controversial changes in guidance, 15 state and territorial leaders have come together to create the Governor’s Public Health Alliance.

Here’s what to know about the new coalition.
US Governors Launch Multistate Public Health Coalition
This Medical News article discusses a new state-led coalition, called the Governors Public Health Alliance, to bolster disease detection and response as federal support wanes.
jamanetwork.com
November 21, 2025 at 4:26 PM
Reposted by Christopher Seymour
jama.com
🧵 JAMA, @jamainternalmed.com, and @jamanetworkopen.com conclude #KidneyWk with impactful findings:

In stable AKI patients, indication-based dialysis enabled faster liberation from dialysis and reduced health care resource use compared to conventional thrice-weekly treatment.

ja.ma/4nIK3Mo
November 8, 2025 at 1:01 AM
Reposted by Christopher Seymour
jama.com
In the latest episode of the JAMA Editor's Summary podcast, JAMA Deputy Editors Linda Brubaker, MD, and Preeti Malani, MD, MSJ, discuss the latest science published in JAMA:

➡️ JAMA at Kidney Week
➡️ JAMA Summit Report on Firearm Violence Reduction, and more

ja.ma/4nNumDM
Image shows two JAMA journals stacked, with the text "jama.com JAMA Research" visible on both. Below, text reads: "19M AGO 10 MIN JAMA at Kidney Week, JAMA Summit Report on Firearm... JAMA Editors' Summary" followed by a purple 'Play' button.
November 8, 2025 at 12:00 AM
Reposted by Christopher Seymour
hbgmd.bsky.social
🙄 Do intensivists ever agree on anything?

Peter Nauka & colleagues 👀 at variability in how we approach respiratory support for ICU patients:

www.chestcc.org/article/S294...

🫣 SPOILER ALERT: nope, we don’t agree

Happy 👻🎃 from #journal_CHESTCritCare!

@seymoc.bsky.social
@accpchest.bsky.social
October 31, 2025 at 8:54 PM
Reposted by Christopher Seymour
jama.com
SOFA-2, validated in >3 million ICU patients, incorporates contemporary organ support and treatments, showing strong predictive validity for ICU mortality in diverse international settings.

#LIVES2025 @esicm.bsky.social

ja.ma/4hE2H70
JAMA article published online October 29, 2025, titled: Development and Validation of the Sequential Organ Failure Assessment (SOFA)-2 Score. Figure 3 shows distribution and ICU Mortality for SOFA-1 and SOFA-2 at ICU Admission.
October 29, 2025 at 1:05 PM
Reposted by Christopher Seymour
jama.com
💬 Editorial: SOFA-2 improves the measurement of organ failure in intensive care by integrating current treatments and data-driven criteria, but further research is needed to address persistent challenges and optimize bedside utility.

#LIVES2025 @esicm.bsky.social

ja.ma/47pxgZb
JAMA editorial, published online October 29, 2025, titled "A Revision to Organ Failure Assessment in Critically Ill Patients" by Christopher W. Seymour, MD, MSc. Discusses modern intensive care and the Sequential Organ Function Assessment (SOFA) score.
October 29, 2025 at 1:10 PM
Reposted by Christopher Seymour
jama.com
📚 Development and Validation of the Sequential Organ Failure Assessment (SOFA)-2 Score:

Presented today in the #LIVES2025 Hot Topics session.

🔗 Free to read online: ja.ma/4qzouAz
Image reads: "Read papers from the JAMA Network." The ESICM logo is in the upper left, with the JAMA Network logo in the upper right. The background is a gradient of red.
October 29, 2025 at 1:15 PM
Reposted by Christopher Seymour
jama.com
From @jamanetworkopen.com: The SOFA-2 score updates the 1996 Sequential Organ Failure Assessment, reflecting current definitions, variables, and thresholds to grade organ dysfunction in critically ill adults receiving intensive care.

#LIVES2025 @esicm.bsky.social

ja.ma/3JuguA7
JAMA Network Open article excerpt: "Rationale and Methodological Approach Underlying the Development of the Sequential Organ Failure Assessment (SOFA)-2 Score." Table details SOFA-2 and SOFA-1 score differences across organ systems.
October 29, 2025 at 1:15 PM
Reposted by Christopher Seymour
jama.com
For #criticallyill patients who had both severe metabolic acidemia and moderate to severe acute kidney injury, sodium bicarbonate therapy did not significantly decrease day 90 all-cause mortality.

#LIVES2025 @esicm.bsky.social

ja.ma/3Ll9Exv
JAMA study: For severe metabolic acidosis and acute kidney injury patients, sodium bicarbonate infusion doesn't decrease all-cause mortality at 90 days. Population: 379 men, 248 women, mean age 67, across 43 French ICUs. Findings: Sodium bicarbonate 62.1%, Control 61.7%.
October 29, 2025 at 1:20 PM
Reposted by Christopher Seymour
jama.com
📚 Personalized Hemodynamic Resuscitation Targeting Capillary Refill Time in Early Septic Shock: The ANDROMEDA-SHOCK-2 Randomized Clinical Trial:

➡️ Presented today in the #LIVES2025 Hot Topics session.

🔗 Free to read online:

ja.ma/4oIaiUe
Text on a gradient red background reads: 'Read papers from the JAMA Network'. Logos for ESICM (in black box) and JAMA Network are also displayed. The background gradient goes from bright to dark red.
October 29, 2025 at 1:45 PM
Reposted by Christopher Seymour
jama.com
In this episode of the JAMA Author Interviews podcast, coauthor Mervyn Singer, MD, discusses the development and validation of the Sequential Organ Failure Assessment (SOFA)-2 score with JAMA Associate Editor Christopher Seymour, MD, MSc.

🎧 Listen now:

ja.ma/47wiUX0
https://ja.ma/4oJNbst
JAMA Author Interviews
ja.ma
October 29, 2025 at 2:00 PM
Reposted by Christopher Seymour
thedeerwhisperer.bsky.social
Seattle in the Fall
📸Susan Kapp
The Space Needle rising above Fall foliage
October 22, 2025 at 5:03 PM
Reposted by Christopher Seymour
jama.com
Postpartum hemorrhage is an obstetric emergency that has an incidence of 3% to 6% of births and accounts for approximately 27% of maternal deaths worldwide.

Learn more about the risk factors, assessment, and management of PPH: ja.ma/4qC9DFM
JAMA Insights graphic on Women's Health, titled "Postpartum Hemorrhage." It outlines a management algorithm for immediate postpartum bleeding, including steps like gentle traction, uterine massage, IV access, and evaluation of bleeding etiology.
October 22, 2025 at 4:30 PM
Reposted by Christopher Seymour
criticalcarereviews.com
There are now just under 50 days to CCR Down Under 2025.

The programme is out - 8 superb trial results coming up.

Join us in Melbourne, in person or virtually, to discuss the best critical care trials in the world!

criticalcarereviews.com/meetings/ccr...
October 21, 2025 at 8:11 PM
Reposted by Christopher Seymour
medicine.stitches.today
Using incisional negative pressure wound therapy after emergency laparotomy did not reduce surgical site infections compared to standard dressings.

by None None, Atherton K (...) Wilkin R et 20 al. in JAMA #MedSky

📖 read the article:
Incisional Negative Pressure Wound Therapy in Emergency Laparotomy
This randomized clinical trial investigates whether incisional negative pressure wound therapy following emergency laparotomy in UK- and Australia-based patients prevented surgical site infection at higher rates than the surgeon’s choice of wound dressing.
jamanetwork.com
March 20, 2025 at 12:53 PM
Reposted by Christopher Seymour
jama.com
Among patients with moderate to severe ARDS, inhaled sedation with sevoflurane resulted in fewer ventilator-free days at day 28 and lower 90-day survival than sedation with propofol. https://ja.ma/4kxDZGm #ISICEM25
Visual Abstract. Inhaled Sedation in Acute Respiratory Distress Syndrome
March 18, 2025 at 7:50 AM
Reposted by Christopher Seymour
jama.com
🧵 This week, JAMA EIC @kbibbinsdomingo.bsky.social, JAMA Associate Editor Kimmie Ng of @danafarber.bsky.social and VP Hannah Park visited research institutions in Mexico City and Cuernavaca to learn about the research being conducted there and present about trends in medical publishing.
March 13, 2025 at 5:24 PM
Reposted by Christopher Seymour
criticalcarereviews.com
The provisional schedule for the Critical Care Reviews Meeting 2025 is now available

12 major trial results across 3 days

CCR25 is supported by @visitbelfast.bsky.social @belfastcc.bsky.social @belfasttrust.bsky.social & Tourism Northern Ireland

criticalcarereviews.com/meetings/ccr25
March 10, 2025 at 1:11 PM
Reposted by Christopher Seymour
criticalcarereviews.com
🚩 Just out in @thelancet.bsky.social 🚩

African Critical Illness Outcome Study

➡️ Describing the burden of critical care in Africa
➡️ 1 in 8 inpatients are critically ill
➡️ ~70% cared for on general wards
➡️ ~50 don't receive basic critical care interventions

doi.org/10.1016/S014...
February 28, 2025 at 9:22 AM
Reposted by Christopher Seymour
jama.com
This Viewpoint explores the addition of host-directed therapy using immunotherapeutic agents to pandemic preparedness programs.

ja.ma/3CWmzlW

#MedSky
February 27, 2025 at 4:52 PM
Reposted by Christopher Seymour
jama.com
In critically ill adults with suspected sepsis, antibiotic regimens were safely reduced when guided by measurement of procalcitonin but not by C-reactive protein.

ja.ma/3D8YB72

#MedSky
February 25, 2025 at 8:41 PM
Reposted by Christopher Seymour
jama.com
For the first time, the Biomedical Advanced Research and Development Authority (BARDA) has funded a trial at retail pharmacies in an effort to reach more diverse patients, speed recruitment, and improve outcomes.

ja.ma/4gHScy7
Retail Pharmacies Get US Funding for Decentralized Trials
This Medical News article discusses a new program to enroll underrepresented communities in decentralized clinical trials.
ja.ma
January 8, 2025 at 3:54 PM
Reposted by Christopher Seymour
jama.com
18.5% of patients who left the emergency department without being seen returned within 7 days, often due to difficulties in accessing non-ED care.

ja.ma/3ZXrIRS
Figure. Time Intervala Between Left Without Being Seen and Return Emergency Department (ED) Visit
January 6, 2025 at 7:19 PM
Reposted by Christopher Seymour
criticalcarereviews.com
Fantastic podcast covering the 4 trials presented at #CCRdownunder and simultaneously published in @jama.com

@kbibbinsdomingo.bsky.social (JAMA EiC) with Chris Seymour (CC editor) & Derek Angus (senior editor)

edhub.ama-assn.org/jn-learning/...
JAMA Research at Critical Care Reviews 2024 (CCR Down Under)
JAMA Senior Editor Derek Angus, MD, MPH, and JAMA Associate Editor Christopher Seymour, MD, MSc, discuss 4 critical care trials published in JAMA and simultaneously presented at the 2024 CCR Down Under meeting in Melbourne, Australia, with JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS.
edhub.ama-assn.org
December 11, 2024 at 4:57 AM