Sean Escola
@seanescola.bsky.social
Came for the neuro; stayed for the AI. https://sean-escola.github.io/
Reposted by Sean Escola
Introducing CorText: a framework that fuses brain data directly into a large language model, allowing for interactive neural readout using natural language.
tl;dr: you can now chat with a brain scan 🧠💬
1/n
tl;dr: you can now chat with a brain scan 🧠💬
1/n
November 3, 2025 at 3:17 PM
Introducing CorText: a framework that fuses brain data directly into a large language model, allowing for interactive neural readout using natural language.
tl;dr: you can now chat with a brain scan 🧠💬
1/n
tl;dr: you can now chat with a brain scan 🧠💬
1/n
Awesome work from @maxhodak.bsky.social and the Science Corp team
Very excited that the clinical trial results for our PRIMA retinal prosthesis are published today in the New England Journal of Medicine! This is the first time that patients who are blind due to photoreceptor loss have been able to intuitively see again.
www.youtube.com/watch?v=J_qT...
www.youtube.com/watch?v=J_qT...
A global mission to restore vision | PRIMA by Science
YouTube video by Science
www.youtube.com
October 21, 2025 at 10:03 AM
Awesome work from @maxhodak.bsky.social and the Science Corp team
Can’t recommend this opportunity strongly enough!!
Interested in doing a Ph.D. to work on building models of the brain/behavior? Consider applying to graduate schools at CU Anschutz:
1. Neuroscience www.cuanschutz.edu/graduate-pro...
2. Bioengineering engineering.ucdenver.edu/bioengineeri...
You could work with several comp neuro PIs, including me.
1. Neuroscience www.cuanschutz.edu/graduate-pro...
2. Bioengineering engineering.ucdenver.edu/bioengineeri...
You could work with several comp neuro PIs, including me.
September 28, 2025 at 7:04 AM
Can’t recommend this opportunity strongly enough!!
Reposted by Sean Escola
An exciting collaboration is underway. @thetransmitter.bsky.social is partnering with @neuromatch.bsky.social to serve the computational neuroscience community and help connect neuroscientists across all career stages.
www.thetransmitter.org/neuromatch-p...
#neuroskyence
www.thetransmitter.org/neuromatch-p...
#neuroskyence
July 18, 2025 at 2:28 PM
An exciting collaboration is underway. @thetransmitter.bsky.social is partnering with @neuromatch.bsky.social to serve the computational neuroscience community and help connect neuroscientists across all career stages.
www.thetransmitter.org/neuromatch-p...
#neuroskyence
www.thetransmitter.org/neuromatch-p...
#neuroskyence
Reposted by Sean Escola
typical corrupt science
May 17, 2025 at 10:20 PM
typical corrupt science
Reposted by Sean Escola
Eva Dyer and I wrote an opinion piece for @thetransmitter.bsky.social on why neuroscience needs to embrace complexity and accept the "bitter lesson" by using a data-driven regime at scale.
With commentary from several wonderful researchers!
🧠📈 #NeuroAI 🧪
With commentary from several wonderful researchers!
🧠📈 #NeuroAI 🧪
How can we make progress in developing a general model of neural computation rather than a series of disjointed models tied to specific experimental circumstances, ask Eva Dyer and @tyrellturing.bsky.social in the latest entry in our NeuroAI series.
www.thetransmitter.org/neuroai/acce...
www.thetransmitter.org/neuroai/acce...
Accepting “bitter lesson” and embracing brain’s complexity
To gain insight into complex neural data, we must move toward a data-driven regime, employing large models trained on vast amounts of data. Experts weigh in.
www.thetransmitter.org
March 26, 2025 at 5:20 PM
Eva Dyer and I wrote an opinion piece for @thetransmitter.bsky.social on why neuroscience needs to embrace complexity and accept the "bitter lesson" by using a data-driven regime at scale.
With commentary from several wonderful researchers!
🧠📈 #NeuroAI 🧪
With commentary from several wonderful researchers!
🧠📈 #NeuroAI 🧪
Reposted by Sean Escola
It's critical for everyone to remember what an Executive Order is. It is the President communicating orders to members of the executive branch. Policies to pursue, actions to take, etc. They are not laws. They are not close to being laws. They are formalized memos to employees. That's all.
March 25, 2025 at 11:53 PM
It's critical for everyone to remember what an Executive Order is. It is the President communicating orders to members of the executive branch. Policies to pursue, actions to take, etc. They are not laws. They are not close to being laws. They are formalized memos to employees. That's all.
Reposted by Sean Escola
Not to toot my own horn, but Neuromatch's NeuroAI course is one of the best places to learn about this exciting area of neuroscience. Students and postdocs, apply!
🚨 Neuromatch Academy Course Applications are OPEN for 2025!! 🚨
Get your application in early to be a student or teaching assistant for this year’s courses!
Applications are due Sunday, March 23.
Apply & learn more: neuromatch.io/courses/
#mlsky #compneurosky #ai #climatesolutions #ScienceEdu 🧪
Get your application in early to be a student or teaching assistant for this year’s courses!
Applications are due Sunday, March 23.
Apply & learn more: neuromatch.io/courses/
#mlsky #compneurosky #ai #climatesolutions #ScienceEdu 🧪
March 17, 2025 at 6:20 PM
Not to toot my own horn, but Neuromatch's NeuroAI course is one of the best places to learn about this exciting area of neuroscience. Students and postdocs, apply!
Reposted by Sean Escola
🌟 Teaching Assistants are who make
Neuromatch Academy run! 🌟
Thinking of becoming a Teaching Assistant (TA) for
Neuromatch or Climatematch Academy? Here’s why you should GO
FOR IT! 🚀
Learn more and apply here: neuromatch.io/courses/
#Education #TA #TeachingOpportunity #mentorship
Neuromatch Academy run! 🌟
Thinking of becoming a Teaching Assistant (TA) for
Neuromatch or Climatematch Academy? Here’s why you should GO
FOR IT! 🚀
Learn more and apply here: neuromatch.io/courses/
#Education #TA #TeachingOpportunity #mentorship
March 17, 2025 at 5:05 PM
🌟 Teaching Assistants are who make
Neuromatch Academy run! 🌟
Thinking of becoming a Teaching Assistant (TA) for
Neuromatch or Climatematch Academy? Here’s why you should GO
FOR IT! 🚀
Learn more and apply here: neuromatch.io/courses/
#Education #TA #TeachingOpportunity #mentorship
Neuromatch Academy run! 🌟
Thinking of becoming a Teaching Assistant (TA) for
Neuromatch or Climatematch Academy? Here’s why you should GO
FOR IT! 🚀
Learn more and apply here: neuromatch.io/courses/
#Education #TA #TeachingOpportunity #mentorship
Do some science! Make some friends!
🚨 Neuromatch Academy Course Applications are OPEN for 2025!! 🚨
Get your application in early to be a student or teaching assistant for this year’s courses!
Applications are due Sunday, March 23.
Apply & learn more: neuromatch.io/courses/
#mlsky #compneurosky #ai #climatesolutions #ScienceEdu 🧪
Get your application in early to be a student or teaching assistant for this year’s courses!
Applications are due Sunday, March 23.
Apply & learn more: neuromatch.io/courses/
#mlsky #compneurosky #ai #climatesolutions #ScienceEdu 🧪
March 5, 2025 at 2:18 AM
Do some science! Make some friends!
Reposted by Sean Escola
At the moment, mansion-sized Asteroid 2024-YR4 has a one-in-fifty chance of hitting Earth in the next eight years.
Now might be a bad time to reduce spending on Science. Just sayin’.
Now might be a bad time to reduce spending on Science. Just sayin’.
February 15, 2025 at 3:27 AM
At the moment, mansion-sized Asteroid 2024-YR4 has a one-in-fifty chance of hitting Earth in the next eight years.
Now might be a bad time to reduce spending on Science. Just sayin’.
Now might be a bad time to reduce spending on Science. Just sayin’.
Reposted by Sean Escola
(1/30) New preprint! "Symmetries and continuous attractors in disordered neural circuits" with Larry Abbott and Haim Sompolinsky
bioRxiv: www.biorxiv.org/content/10.1...
bioRxiv: www.biorxiv.org/content/10.1...
Symmetries and Continuous Attractors in Disordered Neural Circuits
A major challenge in neuroscience is reconciling idealized theoretical models with complex, heterogeneous experimental data. We address this challenge through the lens of continuous-attractor networks...
www.biorxiv.org
January 29, 2025 at 6:26 PM
(1/30) New preprint! "Symmetries and continuous attractors in disordered neural circuits" with Larry Abbott and Haim Sompolinsky
bioRxiv: www.biorxiv.org/content/10.1...
bioRxiv: www.biorxiv.org/content/10.1...
Reposted by Sean Escola
Remember how, when the lockdowns started, every organization said "we only have two weeks of cash on hand and will shut down if we don't get assistance"? That's basically happening to every single lab and NGO right now, except for no actual reason.
January 28, 2025 at 11:11 AM
Remember how, when the lockdowns started, every organization said "we only have two weeks of cash on hand and will shut down if we don't get assistance"? That's basically happening to every single lab and NGO right now, except for no actual reason.
Reposted by Sean Escola
Worth also pointing out that there are many "tests so easy no AI system can pass them".
Moravec's paradox remains.
E.g., arxiv.org/abs/2404.12390
Moravec's paradox remains.
E.g., arxiv.org/abs/2404.12390
January 23, 2025 at 4:54 PM
Worth also pointing out that there are many "tests so easy no AI system can pass them".
Moravec's paradox remains.
E.g., arxiv.org/abs/2404.12390
Moravec's paradox remains.
E.g., arxiv.org/abs/2404.12390
Reposted by Sean Escola
🚀 Calling all visionary scientists and engineers! Announcing our call for Focused Research Organization proposals in the UK. 🔬Submit your concept paper by Feb 7 & full proposal by March 28. More here: www.convergentresearch.org/frost-uk ⤵️
FROST UK — Convergent Research
www.convergentresearch.org
January 8, 2025 at 10:44 PM
🚀 Calling all visionary scientists and engineers! Announcing our call for Focused Research Organization proposals in the UK. 🔬Submit your concept paper by Feb 7 & full proposal by March 28. More here: www.convergentresearch.org/frost-uk ⤵️
Reposted by Sean Escola
I don't think traditional systems neuroscience fits my definition, as it has rarely concerned itself with general principles of intelligence that apply to non-biological systems.
December 26, 2024 at 4:20 PM
I don't think traditional systems neuroscience fits my definition, as it has rarely concerned itself with general principles of intelligence that apply to non-biological systems.
Reposted by Sean Escola
So, they set up the ARC prize specifically to have limits on how much compute you can use, required the submissions to be open-sourced, and then OpenAI just went ahead and crushed it with >$1m of compute from a closed model with no idea how it works anyway? Do I have that right?
December 23, 2024 at 12:44 PM
So, they set up the ARC prize specifically to have limits on how much compute you can use, required the submissions to be open-sourced, and then OpenAI just went ahead and crushed it with >$1m of compute from a closed model with no idea how it works anyway? Do I have that right?
I like this definition (although it’s not the one I’ve typically espoused). It basically says that #NeuroAI is intelligence science writ large. And the name works because our current options for intelligence are either neural or artificial
Well I had another definition but more important than to have consensus is what we aspire to accomplish with the new enthusiasm in #NeuroAI
@tonyzador.bsky.social @kordinglab.bsky.social @shahabbakht.bsky.social @tyrellturing.bsky.social
@tonyzador.bsky.social @kordinglab.bsky.social @shahabbakht.bsky.social @tyrellturing.bsky.social
December 15, 2024 at 3:52 AM
I like this definition (although it’s not the one I’ve typically espoused). It basically says that #NeuroAI is intelligence science writ large. And the name works because our current options for intelligence are either neural or artificial
Have a read of @davidamarkowitz.bsky.social’s proposal to accelerate intelligence science with new institutions in @thetransmitter.bsky.social #NeuroAI
We're at the threshold of understanding intelligence itself. The convergence of neuroscience and AI has created an unprecedented opportunity — but our research ecosystem isn't built to seize it.
We need a new model that matches the scale of our ambition... 🧵
We need a new model that matches the scale of our ambition... 🧵
December 13, 2024 at 7:01 PM
Have a read of @davidamarkowitz.bsky.social’s proposal to accelerate intelligence science with new institutions in @thetransmitter.bsky.social #NeuroAI
Reposted by Sean Escola
Estimate from @mbeisen.bsky.social that about $1.5B (3%) of the $50B NIH budget goes to publishing fees.
If we are looking to cut government waste, this might be a good place to start.
If we are looking to cut government waste, this might be a good place to start.
December 3, 2024 at 2:47 AM
Estimate from @mbeisen.bsky.social that about $1.5B (3%) of the $50B NIH budget goes to publishing fees.
If we are looking to cut government waste, this might be a good place to start.
If we are looking to cut government waste, this might be a good place to start.
The magnum opus drops!
Excited to release what we’ve been working on at Amaranth Foundation, our latest whitepaper, NeuroAI for AI safety! A detailed, ambitious roadmap for how neuroscience research can help build safer AI systems while accelerating both virtual neuroscience and neurotech. 1/N
December 2, 2024 at 4:58 PM
The magnum opus drops!
Reposted by Sean Escola
The time is now to argue vociferously for immense societal and economic value of public investment in scientific research. But unfortunately that argument must be made not to the choir in our beautiful blue bubble here, but in the arena of X where said value is now questioned: x.com/suryaganguli...
x.com
x.com
November 19, 2024 at 12:23 PM
The time is now to argue vociferously for immense societal and economic value of public investment in scientific research. But unfortunately that argument must be made not to the choir in our beautiful blue bubble here, but in the arena of X where said value is now questioned: x.com/suryaganguli...
Reposted by Sean Escola
Unpopular opinion: If you are a scientist who doesn't participate in science advocacy outside your filter bubble, you are doing yourself a disservice. Bluesky is intellectually fun, but the people who will soon be making decisions about government science funding priorities are not on here.
November 13, 2024 at 9:16 PM
Unpopular opinion: If you are a scientist who doesn't participate in science advocacy outside your filter bubble, you are doing yourself a disservice. Bluesky is intellectually fun, but the people who will soon be making decisions about government science funding priorities are not on here.
Reposted by Sean Escola
We (w/ @seanescola.bsky.social & K Lakshminarasimhan) recently wrote a review covering different types of thalamocortical models for motor control. Here is a link to a related talk. Giving a wide perspective & discussing a large body of work was both very challenging & rewarding. Thank you, Andrew!
Our latest lab journal club is now up for your viewing pleasure. Laureline Logiaco (MIT, soon CU Anschutz) explains her recent work on models of thalamocortical interactions for biological motor control. www.youtube.com/watch?v=6Z36...
Laureline Logiaco (MIT)
YouTube video by Andrew Pruszynski
www.youtube.com
November 10, 2024 at 10:54 PM
We (w/ @seanescola.bsky.social & K Lakshminarasimhan) recently wrote a review covering different types of thalamocortical models for motor control. Here is a link to a related talk. Giving a wide perspective & discussing a large body of work was both very challenging & rewarding. Thank you, Andrew!
Reposted by Sean Escola
May future generations remember this as a day when the USA turned away from division and hatred and corruption and toward an inclusive, democratic future.
November 5, 2024 at 12:35 PM
May future generations remember this as a day when the USA turned away from division and hatred and corruption and toward an inclusive, democratic future.