Francesco Limone
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sciencelemon92.bsky.social
Francesco Limone
@sciencelemon92.bsky.social
Neuroscientist by day 🔬🧫 Sassy, queer immigrant all the time 🏳️‍🌈🇮🇹 He/they
Postdoc in the Liddelow lab @NYULH previously found @HSCRB @StanleyCentre
Reposted by Francesco Limone
We look forward to seeing you Tomorrow Nov 26 at 2PM for the 2nd IGN SYMPOSIUM. A time for Glia related Science, with open and live discussion with the Italian glia community. See you Tomorrow!!! 
unipd.zoom.us/j/83647074227?…

Italianglianetwork.c
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Home | Italian Glia Network
Italian Glia Network (IGN) was founded in 2023 by a group of passionate scientists dedicated to glia research. IGN has the MISSION of creating a community of scientists interested in glial biology. IG...
Italianglianetwork.com
November 25, 2025 at 12:59 PM
Hi gang! I am giving a short talk at the second @italianglianetwork.bsky.social Symposium on Wednesday EU-afternoon/US-morning. Sign up to tune in!
Application to present at the Second Italian Glia Network Symposium is closing next week. Apply your abstract by Oct 10!!! Do not miss the opportunity to discuss your research in a young and informal community !!! #Glia
November 24, 2025 at 6:22 PM
Reposted by Francesco Limone
"Defining the molecular identity and morphology of glia limitans superficialis astrocytes in vertebrates"
http://dlvr.it/TPKJSH

@liddelowsa.bsky.social @philiphasel.bsky.social & colleagues
@cp-cellreports.bsky.social
#SfN2025
November 18, 2025 at 1:01 AM
Good work takes time sometimes and @brianjjoseph.bsky.social runs long marathons! Glad to be part of such an interesting study, great team work 💪🏼
November 4, 2025 at 3:21 AM
Reposted by Francesco Limone
1/ Excited to share our new study with @brumbaugh-lab.bsky.social, out in @natbiotech.nature.com! P-bodies selectively sequester RNAs encoding cell fate regulators, often from the preceding developmental stage. Releasing these RNAs can drive changes in cell identity. 🧵 www.nature.com/articles/s41...
Selective RNA sequestration in biomolecular condensates directs cell fate transitions - Nature Biotechnology
Stem cell differentiation is controlled by manipulating RNA condensates.
www.nature.com
October 28, 2025 at 4:02 PM
Reposted by Francesco Limone
I am proud to share our work on X-linked Dystonia-Parkinsonism — a rare neurodegenerative movement disorder driven by a SINE-VNTR-Alu retrotransposon insertion in the TAF1 gene.

Read our two companion papers:
🔹 www.biorxiv.org/content/10.1...
🔹 www.biorxiv.org/content/10.1...

🧵 Highlights below!
October 24, 2025 at 4:32 PM
Reposted by Francesco Limone
Proud to present our new paper in @natmetabolism.nature.com

The Neurolipid Atlas: a lipidomics resource for neurodegenerative diseases
lnkd.in/eVzFrmUY

Check out our open-access platform chock-full with iPSC- and 🧠 lipidomics data (www.neurolipidatlas.com).
LinkedIn
This link will take you to a page that’s not on LinkedIn
lnkd.in
September 22, 2025 at 11:02 AM
Reposted by Francesco Limone
Now on bioRxiv! Astrocytes in one brain region (cyan) communicate in expansive networks (magenta). Through tool development, tissue clearing, and many hours on our @zeiss-microscopy.bsky.social Z1, we now know these networks are repeatable across mice, plastic, and specific.
doi.org/10.1101/2025...
July 22, 2025 at 8:54 PM
Reposted by Francesco Limone
Calling all Neuroscience postdocs! 🧠 Share your research through SPiNES (Seminars from Postdocs in Neuroscience: Extramural Series) from the NYUGSoM Department of Neuroscience. Applications close 08/20/25. Apply today! 👉 nyumc.qualtrics.com/jfe/form/SV_...
#Neuroscience #Postdoc #ResearchOpportunity
June 15, 2025 at 4:20 PM
Reposted by Francesco Limone
✨😀Congratulations to postdocs Eyal Rozenfeld and Francesco Limone on being named 2025 Leon Levy Scholars by The New York Academy of Sciences!

@sciencelemon92.bsky.social
@eyalrozenfeld.bsky.social
@moccalin.bsky.social
@liddelowsa.bsky.social

www.nyas.org/press-releas...
The New York Academy of Sciences and the Leon Levy Foundation Announce the 2025 Leon Levy Scholars in Neuroscience - NYAS
The New York Academy of Sciences and the Leon Levy Foundation have announced the 2025 class of Leon Levy Scholars in Neuroscience.
www.nyas.org
May 8, 2025 at 8:48 PM
Reposted by Francesco Limone
And the full paper is here - www.pnas.org/doi/abs/10.1....

Thanks to Dave and Joseph for the nice coverage!
April 9, 2025 at 12:01 AM
Reposted by Francesco Limone
We're disappointed to see Ben Barres's powerful book "The Autobiography of a Transgender Scientist" among the ~400 titles removed from the Naval Academy Library. Needless to say, we're proud to have published his book and will keep it — and his memory — alive.
The Coming Out of a Transgender Scientist
"I know that I am making the right decision because whenever I think about changing my gender role, I am flooded with feelings of relief."
thereader.mitpress.mit.edu
April 8, 2025 at 8:24 PM
Reposted by Francesco Limone
"I stopped seeing my accent as a problem and started to embrace it."

This week's #ScienceWorkingLife: scim.ag/3VpsO7u
As an international scholar, I’m learning to speak up—accent and all
“My ideas matter more than how I sound,” this postdoc writes
scim.ag
December 6, 2024 at 4:59 PM
Reposted by Francesco Limone
@amyxguo.bsky.social from New York, @liddelowsa.bsky.social lab, has characterized the LCN2 tdTomato mice that label reactive #astrocytes & reactive #endothelial cells. First timer at the #GRCGlia2025, she's done great asking good questions. Definitely one to follow 🔬🧬🍅✨ med.nyu.edu/faculty/shan...
March 13, 2025 at 6:12 PM
Reposted by Francesco Limone
🚨The first #preprint of the #FalconeLab is OUT!🥹🚨

We found that varicose-projection astrocytes are not a physiological type of #astrocytes but they are rather associated with neuropathology.

Read more here, feedback is welcome!!

More details👇👇
1/
www.biorxiv.org/content/10.1...
Varicose-projection astrocytes: a reactive phenotype associated with neuropathology
Glial cells are fundamental for the pathophysiology of all neurological disorders. Astrocytes, the primary homeostatic cells of the central nervous system (CNS), exhibit species-specific characteristi...
www.biorxiv.org
March 18, 2025 at 3:42 PM
Reposted by Francesco Limone
Check out my postdoc work at Ariel Levine’s lab, hot and fresh, describing how you build a dorsal horn!

www.biorxiv.org/content/10.1...
March 17, 2025 at 4:16 PM
Reposted by Francesco Limone
Fresh off the press! We found that degeneration in one retina causes astrocytes to respond retinotopically across *both* hemispheres of the brain. Perhaps astrocytes across the CNS are able to coordinate their responses more than we anticipated... www.pnas.org/doi/10.1073/...
March 10, 2025 at 9:13 PM
Reposted by Francesco Limone
I’m happy to share a free new resource to explore published single cell transcriptomic datasets from the Sanofi Rare and Neurologic Diseases Therapeutic Area.

talk2data.bioturing.com/sanofibrowser
February 27, 2025 at 5:28 PM
Reposted by Francesco Limone
Our paper on the superficial glia limitans is now published - huge thank you to all co-authors that helped getting this work across the finish line! www.cell.com/cell-reports...
Defining the molecular identity and morphology of glia limitans superficialis astrocytes in vertebrates
Hasel et al. show that molecularly and morphologically specialized astrocytes make up the brain and spinal cord surface, thereby creating the glia limitans superficialis. These astrocytes selectively ...
www.cell.com
February 24, 2025 at 10:44 AM
Reposted by Francesco Limone
Welcome to the Bluesky account for Stand Up for Science 2025!

Keep an eye on this space for updates, event information, and ways to get involved. We can't wait to see everyone #standupforscience2025 on March 7th, both in DC and locations nationwide!

#scienceforall #sciencenotsilence
February 12, 2025 at 5:04 PM
Reposted by Francesco Limone
Super stoked to announce 📣
The *Mosberger lab* is officially open and hiring! We're looking for Research Associates and Postdocs interested in uncovering how the brain makes us move 🧠👋🏻
Learn more and find out how to apply here: mosbergerlab.com
Mosberger Lab
mosbergerlab.com
February 5, 2025 at 4:01 PM
Reposted by Francesco Limone
1/ Pleased to share our review, published today
@natrevimmunol.bsky.social, highlighting how biomolecular condensates enhance the precision and flexibility of gene regulatory networks that guide fate decisions during normal and pathological immune cell development. www.nature.com/articles/s41...
Biomolecular condensates in immune cell fate - Nature Reviews Immunology
Recent studies suggest that biomolecular condensates — membrane-less assemblies of proteins and nucleic acids — are involved in regulating gene expression to ensure proper immune cell development. Thi...
www.nature.com
January 28, 2025 at 4:40 PM
Reposted by Francesco Limone
So excited to share our new @natureportfolio.bsky.social review on modeling human brain development using organoids! 🧠 Loved collaborating with the brilliant @lancasterlab.bsky.social , led by the incredible @marcellabirtele.bsky.social Check it out! 🔬 #Neuroscience #BrainOrganoids rdcu.be/d3llp
Modelling human brain development and disease with organoids
Nature Reviews Molecular Cell Biology - This Roadmap article discusses recent advances in the production and use of brain organoids to understand brain development and associated disorders. The...
rdcu.be
December 12, 2024 at 7:36 PM
Reposted by Francesco Limone
Happy to share our review on how different lipids shape microglial biology in #GLIA journal. 💫 onlinelibrary.wiley.com/doi/full/10....

👉🏽with Gaurav Chopra, Caitlin Randolph, and @katherinewalker.bsky.social
Lipids: Emerging Players of Microglial Biology
Lipids are crucial in mediating microglial metabolism and function. The microglial lipidome is vast and complex, with over 10,000 lipid species. We discuss key lipid classes and their roles in m...
onlinelibrary.wiley.com
December 17, 2024 at 2:46 PM
Reposted by Francesco Limone
Great to see our paper online!

Amazing collaboration with Neal over the years, with lots of help from others in the Pasca group.
Today we report in 𝘾𝙚𝙡𝙡 𝙎𝙩𝙚𝙢 𝘾𝙚𝙡𝙡 a systematic approach to generate neural #organoids resembling various domains of the neural axis
Neal Amin & @kevinkelley.bsky.social developed a multiplexed morphogen screen to generate #organoids that mapped to almost 2/3 of the clusters in the 1st trimester CNS
December 6, 2024 at 9:28 PM