Richard Scheltema LAB
scheltemalab.bsky.social
Richard Scheltema LAB
@scheltemalab.bsky.social
Professor at University of Liverpool
Royal Society Wolfson Fellow
Reposted by Richard Scheltema LAB
Thrilled to share one of our biggest discoveries: “Inceptor binds to and directs insulin towards lysosomal degradation in beta cells”.
doi.org/10.1038/s422...
A tremendous collaborative effort led by JohannaSiehler, Sara Bilekova and other members of the Lickert lab @heikolickert.bsky.social
Inceptor binds to and directs insulin towards lysosomal degradation in β cells - Nature Metabolism
The insulin inhibitory receptor (inceptor) is found to bind to insulin and to regulate insulin stores by directing proinsulin and insulin towards lysosomal degradation.
doi.org
November 25, 2024 at 11:16 AM