Saurav Kumar, PhD
sauravk05.bsky.social
Saurav Kumar, PhD
@sauravk05.bsky.social
Reposted by Saurav Kumar, PhD
Postdoc positions available! Please re-post!

Are you interested in how viruses manipulate chromatin? Are you excited to discover unknown facets of molecular biology? If so, we’d love to hear from you! Come check us out at:
avgoustilab.org
Avgousti Lab
Investigating viral manipulation of host chromatin dynamics
avgoustilab.org
June 26, 2025 at 8:24 PM
Reposted by Saurav Kumar, PhD
🧪 Ready, set, degrade!

So proud to share our work in the @jclinical-invest.bsky.social, establishing a versatile approach for creating transgenic dTAG mice to degrade oncoproteins. We showcase that KRAS G12V degradation triggers antitumor immunity in lung cancer.

Link: www.jci.org/articles/vie...
December 27, 2024 at 5:04 PM
Reposted by Saurav Kumar, PhD
A few months old now, but was just rereading this excellent review on molecular glue degraders from Ning Zheng and coworkers #chemsky #tpd
www.sciencedirect.com/science/arti...
Emerging strategies for prospective discovery of molecular glue degraders
Molecular glue (MG) degraders are monovalent small molecule compounds that co-opt E3 ubiquitin ligases to target neo-substrates for proteasomal degrad…
www.sciencedirect.com
November 25, 2024 at 7:05 PM