Saskia Stenzel
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saskiastenzel.bsky.social
Saskia Stenzel
@saskiastenzel.bsky.social
BIF PhD Fellow at Max Planck Institute for Metabolism Research
Studying how neural circuits shape feeding behavior 🐭🧠🧁
Reposted by Saskia Stenzel
Thanks to @nature.com for featuring our work in this piece on genetically-encoded sensors.

The article does a great job highlighting their importance for both basic research and translational impact, such as in our lab's research on serotonin.

www.nature.com/articles/d41...
How genetically encoded sensors have lit up neuroscience
Tools that track specific molecules in neurons have enabled researchers to probe previously unexplored aspects of neurobiology — although important caveats remain.
www.nature.com
November 21, 2025 at 5:56 PM
Reposted by Saskia Stenzel
Thrilled to share our new paper, out now in @natneuro.nature.com, uncovering how estradiol, the most potent estrogen, modulates reinforcement learning and reward prediction errors across biological levels. www.nature.com/articles/s41...

#blueprint 1/7
Estrogen modulates reward prediction errors and reinforcement learning - Nature Neuroscience
Dopamine encoding of reward prediction errors naturally fluctuates over females’ reproductive cycles with estrogenic signaling due to reduced expression of dopamine reuptake proteins.
www.nature.com
November 11, 2025 at 2:41 PM
Reposted by Saskia Stenzel
Out today in Nature: We uncover a neural mechanism for the integration of two internal states - hunger and estrous state - and how this integration shapes pup-directed behaviors in mice.
www.nature.com/articles/s41...
Integration of hunger and hormonal state gates infant-directed aggression - Nature
Combined behavioural, circuit-level and cellular approaches are used to demonstrate how hypothalamic neurons integrate hunger and oestrous state to drive a switch in how female mice interact with pups...
www.nature.com
October 22, 2025 at 3:30 PM