Saruby Sharma
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sarubysharma.bsky.social
Saruby Sharma
@sarubysharma.bsky.social
6 followers 27 following 0 posts
PhD student
Structure and function of molecular machines
University Medical Center Göttingen, Germany
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Reposted by Saruby Sharma
science.org
Happy 158th Birthday, Marie Skłodowska Curie! She was the first woman to receive a Nobel Prize and the first person to receive the honor twice.

In 2017, #ScienceBooks toured the dynamics that established her as "the most iconic of all female scientists." https://scim.ag/47tkKYA
The making and remaking of Marie Curie
The famous physicist's legacy looms large 150 years after her birth
www.science.org
November 7, 2025 at 2:47 PM
Reposted by Saruby Sharma
cellpress.bsky.social
Scientists cut down time needed to grow #transgenic plants from months to weeks by hijacking plants' natural ability to regenerate. spkl.io/63323Awel7

Gunvant B. Patil & colleagues
@mplantpcom.bsky.social
Schematic diagrams of the constructs and transfection strategies (A) Construct showing a gRNA targeting the tobacco PDS gene driven by Arabidopsis U6-snRNA26 (U6-26) promoter, AtWIND1 driven by the CaMV 35S promoter, an AtESR1 promoter driving different DRs (one DR in each construct), and a visible reporter gene, RUBY driven by the CmYLCV promoter within the T-DNA border. (B) Three different in planta transformation strategies in tobacco. After testing three different transfection strategies, only the third strategy led to de novo shoot formation. Therefore, we employed only the third strategy in tomato (C) and soybean (D). (C) Schematic diagram of the construct and in planta transfection and regeneration strategy in tomato. (D) Schematic diagram of the construct (top) for in planta (resulted in callus formation but unsuccessful shoot regeneration) and (bottom) semi-in planta transfection and regeneration strategy in soybean.
November 6, 2025 at 4:00 PM
Reposted by Saruby Sharma
haukehillen.bsky.social
The peer-reviewed version of our paper on human tRNA 3' processing is now published in
@naturesmb.bsky.social :
www.nature.com/articles/s41...
Many thanks to the reviewers for their constructive comments!

See also the great complementary work by the Hällberg lab: www.embopress.org/doi/full/10....
Molecular basis of human nuclear and mitochondrial tRNA 3′ processing - Nature Structural & Molecular Biology
Bhatta et al. use biochemistry and cryogenic electron microscopy to elucidate the mechanism of human tRNA 3′ processing. Their results show how mitochondria-specific subunits of RNase Z compensate for...
www.nature.com
January 11, 2025 at 12:37 PM