Sara Chelaghma
@sarachelaghma.bsky.social
🇩🇿 PhD student in Ross Waller’s lab.
Team Toxoplasma. Investigating the apicoplast.
Team Toxoplasma. Investigating the apicoplast.
Reposted by Sara Chelaghma
🌟 Ready to take the next step in your career?
Applications are open for the Cambridge Biosciences Doctoral Training Programme! 🔬
➡️ Fully funded opportunities: supported by the BBSRC
Learn more and apply now: bbsrcdtp.lifesci.cam.ac.uk/how-apply
#Postgraduate #Cambridge #PhD
Applications are open for the Cambridge Biosciences Doctoral Training Programme! 🔬
➡️ Fully funded opportunities: supported by the BBSRC
Learn more and apply now: bbsrcdtp.lifesci.cam.ac.uk/how-apply
#Postgraduate #Cambridge #PhD
November 11, 2025 at 5:19 PM
🌟 Ready to take the next step in your career?
Applications are open for the Cambridge Biosciences Doctoral Training Programme! 🔬
➡️ Fully funded opportunities: supported by the BBSRC
Learn more and apply now: bbsrcdtp.lifesci.cam.ac.uk/how-apply
#Postgraduate #Cambridge #PhD
Applications are open for the Cambridge Biosciences Doctoral Training Programme! 🔬
➡️ Fully funded opportunities: supported by the BBSRC
Learn more and apply now: bbsrcdtp.lifesci.cam.ac.uk/how-apply
#Postgraduate #Cambridge #PhD
Reposted by Sara Chelaghma
We’re back with the next DinoSphere Online Seminar!
Join us on Nov 4th, we're hosting:
Edmée Royen (ULiège) - Symbiodinium
Nicolas dos Santos Pacheco (Cambridge) - Perkinsids
📅 Tue, Nov 4 - 4 PM CET/3 PM GMT
💻 Zoom link: sites.google.com/view/dinosphere
Please spread the word!
#protistonsky
Join us on Nov 4th, we're hosting:
Edmée Royen (ULiège) - Symbiodinium
Nicolas dos Santos Pacheco (Cambridge) - Perkinsids
📅 Tue, Nov 4 - 4 PM CET/3 PM GMT
💻 Zoom link: sites.google.com/view/dinosphere
Please spread the word!
#protistonsky
October 28, 2025 at 3:29 PM
We’re back with the next DinoSphere Online Seminar!
Join us on Nov 4th, we're hosting:
Edmée Royen (ULiège) - Symbiodinium
Nicolas dos Santos Pacheco (Cambridge) - Perkinsids
📅 Tue, Nov 4 - 4 PM CET/3 PM GMT
💻 Zoom link: sites.google.com/view/dinosphere
Please spread the word!
#protistonsky
Join us on Nov 4th, we're hosting:
Edmée Royen (ULiège) - Symbiodinium
Nicolas dos Santos Pacheco (Cambridge) - Perkinsids
📅 Tue, Nov 4 - 4 PM CET/3 PM GMT
💻 Zoom link: sites.google.com/view/dinosphere
Please spread the word!
#protistonsky
Reposted by Sara Chelaghma
Who-cysts? OOCYSTS! That's right, it's almost time for ❄️Coccidia UK 2025❄️
Your one-stop shop (/conference) for all like-minded sporulating apicomplexan parasites! This year we're in London @crick.ac.uk, looking forward to welcoming parasitologists from across the UK. Register-
tinyurl.com/4ny5bwu2
Your one-stop shop (/conference) for all like-minded sporulating apicomplexan parasites! This year we're in London @crick.ac.uk, looking forward to welcoming parasitologists from across the UK. Register-
tinyurl.com/4ny5bwu2
CoccidiaUK 2025 registration
DEADLINE FOR ABSTRACT SUBMISSION: NOVEMBER 7th
Event Timing: December 8th 9am-5pm
December 9th 9am-12pm
Event Address: The Francis Crick Institute
Questions? please email ada...
tinyurl.com
October 14, 2025 at 4:58 PM
Who-cysts? OOCYSTS! That's right, it's almost time for ❄️Coccidia UK 2025❄️
Your one-stop shop (/conference) for all like-minded sporulating apicomplexan parasites! This year we're in London @crick.ac.uk, looking forward to welcoming parasitologists from across the UK. Register-
tinyurl.com/4ny5bwu2
Your one-stop shop (/conference) for all like-minded sporulating apicomplexan parasites! This year we're in London @crick.ac.uk, looking forward to welcoming parasitologists from across the UK. Register-
tinyurl.com/4ny5bwu2
Reposted by Sara Chelaghma
🚨🚨 New Paper alert! 🚨🚨 :
Evolutionary history, longevity and terrestriality predict Toxoplasma gondii seroprevalence in primates 🌳🐈⬛️🦠🐒. #zoonosis #conservation #primates #wildlife #Madagascar #lemur #parasites
www.sciencedirect.com/science/arti...
Evolutionary history, longevity and terrestriality predict Toxoplasma gondii seroprevalence in primates 🌳🐈⬛️🦠🐒. #zoonosis #conservation #primates #wildlife #Madagascar #lemur #parasites
www.sciencedirect.com/science/arti...
Evolutionary history, longevity and terrestriality predict Toxoplasma gondii seroprevalence in free-ranging non-human primates
Evidence from captive populations indicates that lemurs are particularly vulnerable to toxoplasmosis, a parasitic disease caused by Toxoplasma gondii.…
www.sciencedirect.com
October 3, 2025 at 10:27 PM
🚨🚨 New Paper alert! 🚨🚨 :
Evolutionary history, longevity and terrestriality predict Toxoplasma gondii seroprevalence in primates 🌳🐈⬛️🦠🐒. #zoonosis #conservation #primates #wildlife #Madagascar #lemur #parasites
www.sciencedirect.com/science/arti...
Evolutionary history, longevity and terrestriality predict Toxoplasma gondii seroprevalence in primates 🌳🐈⬛️🦠🐒. #zoonosis #conservation #primates #wildlife #Madagascar #lemur #parasites
www.sciencedirect.com/science/arti...
Reposted by Sara Chelaghma
📣 Open postdoc position in my lab to investigate how Toxoplasma acquires nutrients. Join me at the University of Edinburgh. Closing date 14th August. More details below ⬇️
elxw.fa.em3.oraclecloud.com/hcmUI/Candid...
elxw.fa.em3.oraclecloud.com/hcmUI/Candid...
Postdoctoral Research Associate
We are looking for a talented and enthusiastic Postdoctoral researcher to join the Maclean lab to investigate the metabolism of the human parasite Toxoplasma gondii.
elxw.fa.em3.oraclecloud.com
July 23, 2025 at 10:00 AM
📣 Open postdoc position in my lab to investigate how Toxoplasma acquires nutrients. Join me at the University of Edinburgh. Closing date 14th August. More details below ⬇️
elxw.fa.em3.oraclecloud.com/hcmUI/Candid...
elxw.fa.em3.oraclecloud.com/hcmUI/Candid...
Reposted by Sara Chelaghma
🚨 2-year post-doc position available in my lab. More details below. Please repost!
acrobat.adobe.com/id/urn:aaid:...
acrobat.adobe.com/id/urn:aaid:...
July 29, 2025 at 7:22 AM
🚨 2-year post-doc position available in my lab. More details below. Please repost!
acrobat.adobe.com/id/urn:aaid:...
acrobat.adobe.com/id/urn:aaid:...
Very nice work, congratulations to all authors!
Our paper has finally graduated from pre-print to peer-reviewed, pretty much unscathed, and is out now! www.cell.com/cell/fulltex...
The essential host genome for Cryptosporidium survival exposes metabolic dependencies that can be leveraged for treatment
An arrayed microscopy-based CRISPR screen revealed host genes affecting multiple infection
phenotypes of the intracellular parasite Cryptosporidium. Hits in the host cholesterol
biosynthesis pathway a...
www.cell.com
July 25, 2025 at 7:47 AM
Very nice work, congratulations to all authors!
Reposted by Sara Chelaghma
I am looking for a Research Technician! Come join me in my quest to unlock the secrets of Toxoplasma’s RNA-binding proteins and how they help these parasites steal nutrients. Deadline for applications is August 6th! www.jobs.gla.ac.uk/job/technici...
Technician
Job PurposeTo provide in-depth technical expertise in parasitology, cell, and molecular biology and provide advice on the set up and best operation of equipment and procedures to aid delivery objec...
www.jobs.gla.ac.uk
July 17, 2025 at 8:18 PM
I am looking for a Research Technician! Come join me in my quest to unlock the secrets of Toxoplasma’s RNA-binding proteins and how they help these parasites steal nutrients. Deadline for applications is August 6th! www.jobs.gla.ac.uk/job/technici...
Reposted by Sara Chelaghma
Out today in Science: Our work on tropical cyclones and malaria in Madagascar. Work inspired by many and done in collaboration with many www.science.org/doi/10.1126/...
Vaccination to mitigate climate-driven disruptions to malaria control in Madagascar
Extreme weather is common in high malaria burden areas and is likely to increase in severity owing to climate change–related severe weather events. Yet, data on infection rates after these events and ...
www.science.org
July 17, 2025 at 10:10 PM
Out today in Science: Our work on tropical cyclones and malaria in Madagascar. Work inspired by many and done in collaboration with many www.science.org/doi/10.1126/...
Reposted by Sara Chelaghma
Excited, surprised and proud to share the news about my @MaxwellHanrahan Award in Field Biology! The award recognizes my work in infectious disease ecology and wildlife conservation in #Madagascar. To learn more about the award: www.maxwell-hanrahan.org/programs/fie...
July 18, 2025 at 3:37 AM
Excited, surprised and proud to share the news about my @MaxwellHanrahan Award in Field Biology! The award recognizes my work in infectious disease ecology and wildlife conservation in #Madagascar. To learn more about the award: www.maxwell-hanrahan.org/programs/fie...
Reposted by Sara Chelaghma
The anticipation is over, the MPM registration and abstract submission is open!!
Registration and Abstract submission for MPMXXXVI are now open! Abstract submission deadline is June 27th, get yours in quickly. @rmc9z.bsky.social @mjgubbels.bsky.social @omarharb.org
🔗https://www.parasitesrule.com/mpm-xxxvi
🔗https://www.parasitesrule.com/mpm-xxxvi
June 5, 2025 at 5:00 PM
The anticipation is over, the MPM registration and abstract submission is open!!
Reposted by Sara Chelaghma
I got hit by some rather sudden and extreme financial hardship so if anyone is in need of remote wetlab contract research, strictly BSL1, do let me know. Currently scrambling for gigs.
Plant, Bacterial, Archaeal Non-model Bioeng
Custom Lab Hardware
Turn Key Genetic Design
Please repost for reach 💚
Plant, Bacterial, Archaeal Non-model Bioeng
Custom Lab Hardware
Turn Key Genetic Design
Please repost for reach 💚
May 2, 2025 at 2:39 PM
I got hit by some rather sudden and extreme financial hardship so if anyone is in need of remote wetlab contract research, strictly BSL1, do let me know. Currently scrambling for gigs.
Plant, Bacterial, Archaeal Non-model Bioeng
Custom Lab Hardware
Turn Key Genetic Design
Please repost for reach 💚
Plant, Bacterial, Archaeal Non-model Bioeng
Custom Lab Hardware
Turn Key Genetic Design
Please repost for reach 💚
Reposted by Sara Chelaghma
Thrilled to share my first paper, now out in
@natmicrobiol.nature.com! Huge thanks to my amazing supervisor @hakimi.bsky.social and everyone who contributed to this work!
www.nature.com/articles/s41...
@natmicrobiol.nature.com! Huge thanks to my amazing supervisor @hakimi.bsky.social and everyone who contributed to this work!
www.nature.com/articles/s41...
An ISWI-related chromatin remodeller regulates stage-specific gene expression in Toxoplasma gondii - Nature Microbiology
Toxoplasma gondii evolved two ISWI remodellers, TgSNF2h and TgSNF2L. TgSNF2h forms a complex that insulates active genes, regulates MORC-driven sexual commitment and ensures precise gene expression, s...
www.nature.com
April 13, 2025 at 11:03 AM
Thrilled to share my first paper, now out in
@natmicrobiol.nature.com! Huge thanks to my amazing supervisor @hakimi.bsky.social and everyone who contributed to this work!
www.nature.com/articles/s41...
@natmicrobiol.nature.com! Huge thanks to my amazing supervisor @hakimi.bsky.social and everyone who contributed to this work!
www.nature.com/articles/s41...
Reposted by Sara Chelaghma
Check out our dispatch on apicomplexans that infect corals!
www.sciencedirect.com/science/arti...
These parasite-like partners have lost photosynthesis but retained chlorophyll... are they friend or foe?
@currentbiology.bsky.social #protistsonsky #symbiosky #microsky #coralreefs
www.sciencedirect.com/science/arti...
These parasite-like partners have lost photosynthesis but retained chlorophyll... are they friend or foe?
@currentbiology.bsky.social #protistsonsky #symbiosky #microsky #coralreefs
March 13, 2025 at 12:11 PM
Check out our dispatch on apicomplexans that infect corals!
www.sciencedirect.com/science/arti...
These parasite-like partners have lost photosynthesis but retained chlorophyll... are they friend or foe?
@currentbiology.bsky.social #protistsonsky #symbiosky #microsky #coralreefs
www.sciencedirect.com/science/arti...
These parasite-like partners have lost photosynthesis but retained chlorophyll... are they friend or foe?
@currentbiology.bsky.social #protistsonsky #symbiosky #microsky #coralreefs
Reposted by Sara Chelaghma
Do you work on parasites and reside in an LMIC? Consider applying for a 2025 MPM LMIC award. The deadline is March 3rd, 2025—details on the website.
www.parasitesrule.com/mpm-xxxvi/tr...
www.parasitesrule.com/mpm-xxxvi/tr...
Molecular Parasitology Community - Travelaward2025
Scroll down for the application form
www.parasitesrule.com
February 5, 2025 at 2:20 AM
Do you work on parasites and reside in an LMIC? Consider applying for a 2025 MPM LMIC award. The deadline is March 3rd, 2025—details on the website.
www.parasitesrule.com/mpm-xxxvi/tr...
www.parasitesrule.com/mpm-xxxvi/tr...
Reposted by Sara Chelaghma
Our newest paper! Please see a beautiful (and gif-filled!) explained from @sloanmegan.bsky.social below
Excited to be able to share our new paper 'Iron Mediated Post-Transcriptional Regulation in Toxoplasma gondii'! Thanks to all involved including the awesome @clarehardinglab.bsky.social and @danaaghabi.bsky.social! journals.plos.org/plospathogen.... Read on for quick-read digest of our new work...
Iron-mediated post-transcriptional regulation in Toxoplasma gondii
Author summary Although iron is essential for most cells, excess can be toxic, so uptake and storage must be carefully controlled. The ability to respond to iron is particularly important for parasite...
journals.plos.org
February 5, 2025 at 11:55 AM
Our newest paper! Please see a beautiful (and gif-filled!) explained from @sloanmegan.bsky.social below
Reposted by Sara Chelaghma
Our commentary on this excellent paper is available: www.sciencedirect.com/science/arti...
Evolution: Untangling the mix of plastid endosymbiosis events
The demonstration that a plastid protein targeting system remained unchanged following the endosymbiotic transfer to a new host calls into question wh…
www.sciencedirect.com
February 5, 2025 at 12:33 PM
Our commentary on this excellent paper is available: www.sciencedirect.com/science/arti...
Reposted by Sara Chelaghma
Plastids & mitochondria arose from separate endosymbioses of prokaryotes.Their prokaryotic ancestry makes them susceptible to antibiotics. Antibiotics kill pathogenic protists by targeting their plastids or mitochondria. Here we review the lop sided inheritance.
journals.plos.org/plospathogen...
Modes and mechanisms for the inheritance of mitochondria and plastids in pathogenic protists
Pathogenic protists are responsible for many diseases that significantly impact human and animal health across the globe. Almost all protists possess mitochondria or mitochondrion-related organelles, ...
journals.plos.org
January 25, 2025 at 10:29 PM
Plastids & mitochondria arose from separate endosymbioses of prokaryotes.Their prokaryotic ancestry makes them susceptible to antibiotics. Antibiotics kill pathogenic protists by targeting their plastids or mitochondria. Here we review the lop sided inheritance.
journals.plos.org/plospathogen...
Reposted by Sara Chelaghma
The MPM XXXVI page is now live. Sept 14th to Sept 18th. More updates will be coming soon. Check it out on the parasitesrule.com website. Organized this year by Richarch McCulloch @rmc9z.bsky.social, Photini Sinnis, Marc-Jan Gubbels, Deepali Ravel & Omar Harb @omarharb.bsky.social
Molecular Parasitology Community
The MPM XXXVI website is now online
parasitesrule.com
January 21, 2025 at 4:47 PM
The MPM XXXVI page is now live. Sept 14th to Sept 18th. More updates will be coming soon. Check it out on the parasitesrule.com website. Organized this year by Richarch McCulloch @rmc9z.bsky.social, Photini Sinnis, Marc-Jan Gubbels, Deepali Ravel & Omar Harb @omarharb.bsky.social
Reposted by Sara Chelaghma
Thrilled to have this out now! Go checkout our paper about the crazy #Toxoplasma #mitoribosome. Huge thanks to co-authors, collaborators and everyone involved 🙌
Remember learning that ribosomes are made of 1 large subunit RNA + 1 small subunit RNA?
Well, some cells defy this rule, and the most extreme case is Toxoplasma which makes its mitoribosome from >50 RNA pieces!
Wanna know how? Read below
Well, some cells defy this rule, and the most extreme case is Toxoplasma which makes its mitoribosome from >50 RNA pieces!
Wanna know how? Read below
January 21, 2025 at 6:08 PM
Thrilled to have this out now! Go checkout our paper about the crazy #Toxoplasma #mitoribosome. Huge thanks to co-authors, collaborators and everyone involved 🙌
Reposted by Sara Chelaghma
🚨 Retirement Symposium for Prof Mark Carrington of the University of Cambridge
Our #Trypanosoma colleagues may want to attend this symposium in Cambridge on the 𝟐𝟒𝐭𝐡 𝐨𝐟 𝐌𝐚𝐫𝐜𝐡, 2025 (register by the 15th!)
- Details at QR code & tinyurl.com/2uw8tryu
Our #Trypanosoma colleagues may want to attend this symposium in Cambridge on the 𝟐𝟒𝐭𝐡 𝐨𝐟 𝐌𝐚𝐫𝐜𝐡, 2025 (register by the 15th!)
- Details at QR code & tinyurl.com/2uw8tryu
January 16, 2025 at 5:04 PM
🚨 Retirement Symposium for Prof Mark Carrington of the University of Cambridge
Our #Trypanosoma colleagues may want to attend this symposium in Cambridge on the 𝟐𝟒𝐭𝐡 𝐨𝐟 𝐌𝐚𝐫𝐜𝐡, 2025 (register by the 15th!)
- Details at QR code & tinyurl.com/2uw8tryu
Our #Trypanosoma colleagues may want to attend this symposium in Cambridge on the 𝟐𝟒𝐭𝐡 𝐨𝐟 𝐌𝐚𝐫𝐜𝐡, 2025 (register by the 15th!)
- Details at QR code & tinyurl.com/2uw8tryu
Reposted by Sara Chelaghma
📢Reminder that the early bird registration for the 2nd Women in Malaria Online conference is closing Feb 14, 2025 (50 USD)! Fee waiver applications are available for LMICs & you can also buy fee waivers for others. Register/apply here: womeninmalaria.es/wim-conferen... Please re-share 💛
January 8, 2025 at 9:52 AM
📢Reminder that the early bird registration for the 2nd Women in Malaria Online conference is closing Feb 14, 2025 (50 USD)! Fee waiver applications are available for LMICs & you can also buy fee waivers for others. Register/apply here: womeninmalaria.es/wim-conferen... Please re-share 💛