Abstract. Immune function varies widely across humans. Biological sex is a key factor underlying human immune variability, with men presenting with more se

Researchers have discovered how an ion channel in the brain’s neurons has a kind of ‘molecular memory’, which contributes to the formation and preservation of lifelong memories.

Colm Nestor har utsetts till 2025 års mottagare av Onkel Adams pris för framstående forskning vid Medicinska fakulteten. Han forskar om genetiska förklaringar till varför autoimmuna sjukdomar och infe...

Nature Reviews Genetics, Published online: 28 March 2025; doi:10.1038/s41576-025-00822-5Long-read sequencing technologies can directly profile methylation modifications across the genome. In this Review, Fu et al. overview the long-read computational tools to identify and compare methylation signals, as well as tools that use these methylation signals to analyse cell-type diversity and gain additional genomic insights.

X-chromosome inactivation (XCI) contributes to sex bias in T cell immunity, but data on profiling XCI during human T cell development is still lacking. Here, the authors leverage allele-specific expre...