SAND Lab
@sandlab.bsky.social
We are the Synaptic and Network Development (SAND) Group. Our research focuses on understanding microscale functional neuronal networks in development and neurodevelopmental disorders.
Jeremi spotted this cool paper studying Parkinson's disease in midbrain-striatum organoids that assessed the degree of functional connectivity, between different regions of their assembloid on the microelectrode array, using MEA-NAP!
www.nature.com/articles/s42...
www.nature.com/articles/s42...
Modeling early phenotypes of Parkinson’s disease by age-induced midbrain-striatum assembloids - Communications Biology
Generation of a midbrain-striatum assembloid with progerin overexpression as an in vitro model of possessing aging and senescence characteristics for studying Parkinson’s disease.
www.nature.com
December 2, 2024 at 9:37 PM
Jeremi spotted this cool paper studying Parkinson's disease in midbrain-striatum organoids that assessed the degree of functional connectivity, between different regions of their assembloid on the microelectrode array, using MEA-NAP!
www.nature.com/articles/s42...
www.nature.com/articles/s42...
Congrats to Yiwei Gong on posting on arXiv her PhD work featuring our new network dynamics method for MEA data!
arxiv.org/abs/2411.04229 #neuroscience
arxiv.org/abs/2411.04229 #neuroscience
Detecting State Changes in Functional Neuronal Connectivity using Factorial Switching Linear Dynamical Systems
A key question in brain sciences is how to identify time-evolving functional connectivity, such as that obtained from recordings of neuronal activity over time. We wish to explain the observed phenome...
arxiv.org
November 21, 2024 at 8:13 PM
Congrats to Yiwei Gong on posting on arXiv her PhD work featuring our new network dynamics method for MEA data!
arxiv.org/abs/2411.04229 #neuroscience
arxiv.org/abs/2411.04229 #neuroscience
Our MEA-NAP video abstract appears on the Cell Press YouTube channel with an #elephant-showering!!
youtu.be/RJuvSDivApQ?...
youtu.be/RJuvSDivApQ?...
November 20, 2024 at 5:48 PM
Our MEA-NAP video abstract appears on the Cell Press YouTube channel with an #elephant-showering!!
youtu.be/RJuvSDivApQ?...
youtu.be/RJuvSDivApQ?...
Reposted by SAND Lab
3D human brain organoid neuronal network analysis strategies: an exciting collaborative work led by Susanna Mierau - and more to come: www.cell.com/cell-reports...
November 18, 2024 at 6:49 PM
3D human brain organoid neuronal network analysis strategies: an exciting collaborative work led by Susanna Mierau - and more to come: www.cell.com/cell-reports...