Samira Epp (she/her)
samomat.bsky.social
Samira Epp (she/her)
@samomat.bsky.social
Neuroscientist, PostDoc at FAU Nuremberg-Erlangen. Discovering quantitative hemodynamics and metabolism of the human brain.
Reposted by Samira Epp (she/her)
4:
In summary, we identified varying oxygen extraction as a novel hemodynamic response type to neuronal activity, leading to paradoxically inverse BOLD signal responses, particularly in the Default Mode Network.
December 16, 2025 at 3:43 PM
Reposted by Samira Epp (she/her)
2:
We found inconsistent hemodynamic responses via blood flow (CBF) across the cortex and even within the same voxels, depending on task type and baseline oxygen extraction fraction (OEF).
December 16, 2025 at 3:43 PM
Reposted by Samira Epp (she/her)
fMRI signals “up,” but neural metabolism might be going “down.”

In our @natneuro.nature.com paper, we demonstrate that about 40% of voxels with robust BOLD responses exhibit opposite oxygen metabolism, revealing two distinct hemodynamic modes.

rdcu.be/eUPO8
funds @erc.europa.eu
#neuroskyence 🧵:
December 16, 2025 at 3:43 PM