Sam Lipworth
@samlipworth.bsky.social
Academic Clinical Fellow and ID/Micro registrar in Oxford
It's not a video, but @katholt.bsky.social's holtlab.net/tag/comparat... is a good place to start
comparative genomics – Holt Lab
Posts about comparative genomics written by kat
holtlab.net
October 9, 2025 at 11:41 AM
It's not a video, but @katholt.bsky.social's holtlab.net/tag/comparat... is a good place to start
Great collaboration with @ukhsa.bsky.social #HPRU colleagues #nicolestoesser and the NEKSUS consortium of 9 NHS trusts in England
September 18, 2025 at 11:44 AM
Great collaboration with @ukhsa.bsky.social #HPRU colleagues #nicolestoesser and the NEKSUS consortium of 9 NHS trusts in England
Overall, using R10.4.1, super-high accuracy basecalling and autocycler, we can reliably infer marker geens (MLST/ARGs etc) and feel that performance was good enough to drop Illumina sequencing for the NEKSUS study (more to follow in due course!)
September 18, 2025 at 11:38 AM
Overall, using R10.4.1, super-high accuracy basecalling and autocycler, we can reliably infer marker geens (MLST/ARGs etc) and feel that performance was good enough to drop Illumina sequencing for the NEKSUS study (more to follow in due course!)
Dot showed that overall, @rrwick.bsky.social Autocycler appears to outperform other long read assemblers and long read only assemblies are extremely accurate (median Q-score of 67). Long read polishing helps small amount + benefits from short read polishing are very small (only for worst assemblies)
September 18, 2025 at 11:38 AM
Dot showed that overall, @rrwick.bsky.social Autocycler appears to outperform other long read assemblers and long read only assemblies are extremely accurate (median Q-score of 67). Long read polishing helps small amount + benefits from short read polishing are very small (only for worst assemblies)