Sam Lord
@samjlord.bsky.social
Cell biology and microscopy researcher in the @MullinsLab at UCSF. I publish as Samuel J. Lord. https://blog.everydayscientist.com/
There are also cool Violin SuperPlots by Martin Kenny and Ingmar Schoen: www.molbiolcell.org/doi/10.1091/...
November 18, 2024 at 9:13 PM
There are also cool Violin SuperPlots by Martin Kenny and Ingmar Schoen: www.molbiolcell.org/doi/10.1091/...
You an even go as far as to color-code each cell-level datapoint by the experimental run it came from, so the reader can see if there if the cell variability is clustered or dispersed.
November 18, 2024 at 7:02 PM
You an even go as far as to color-code each cell-level datapoint by the experimental run it came from, so the reader can see if there if the cell variability is clustered or dispersed.
So we proposed #SuperPlots, which superimpose sample-to-sample summary data on top of the cell-level distribution. It's a simple way to convey both variability of the underlying data and the repeatability of the experiment. Here, sample means are overlaid on a violin plot of all the cell data.
November 18, 2024 at 7:02 PM
So we proposed #SuperPlots, which superimpose sample-to-sample summary data on top of the cell-level distribution. It's a simple way to convey both variability of the underlying data and the repeatability of the experiment. Here, sample means are overlaid on a violin plot of all the cell data.
Note that all the different experimental scenarios on the right—including random flask-to-flask variability in D—can yield the same plots and tiny error bars in A when we treat each cell as an "n":
November 18, 2024 at 7:02 PM
Note that all the different experimental scenarios on the right—including random flask-to-flask variability in D—can yield the same plots and tiny error bars in A when we treat each cell as an "n":
Q: What's wrong with these plots?
A: Pooling cell-level measurements across multiple runs conceals experimental reproducibility.
Read more in JCB (with @fritzlaylin.bsky.social @katrinavelle.bsky.social & Dyche Mullins): rupress.org/jcb/article/...
A: Pooling cell-level measurements across multiple runs conceals experimental reproducibility.
Read more in JCB (with @fritzlaylin.bsky.social @katrinavelle.bsky.social & Dyche Mullins): rupress.org/jcb/article/...
November 18, 2024 at 7:02 PM
Q: What's wrong with these plots?
A: Pooling cell-level measurements across multiple runs conceals experimental reproducibility.
Read more in JCB (with @fritzlaylin.bsky.social @katrinavelle.bsky.social & Dyche Mullins): rupress.org/jcb/article/...
A: Pooling cell-level measurements across multiple runs conceals experimental reproducibility.
Read more in JCB (with @fritzlaylin.bsky.social @katrinavelle.bsky.social & Dyche Mullins): rupress.org/jcb/article/...
November 18, 2024 at 5:54 AM
We're seeking feedback on our white paper on PeerReplication.
Arthur, Kristen, Dyche, Anders, and I propose an alternative or augmentation to peer review, where key experiments are reproduced, adding robustness to published findings.
zenodo.org/doi/10.5281/...
Arthur, Kristen, Dyche, Anders, and I propose an alternative or augmentation to peer review, where key experiments are reproduced, adding robustness to published findings.
zenodo.org/doi/10.5281/...
November 3, 2023 at 7:55 PM
We're seeking feedback on our white paper on PeerReplication.
Arthur, Kristen, Dyche, Anders, and I propose an alternative or augmentation to peer review, where key experiments are reproduced, adding robustness to published findings.
zenodo.org/doi/10.5281/...
Arthur, Kristen, Dyche, Anders, and I propose an alternative or augmentation to peer review, where key experiments are reproduced, adding robustness to published findings.
zenodo.org/doi/10.5281/...