Sameer Aryal
@sameeraryal.bsky.social
Scientist studying molecular mechanisms of neuropsychiatric disorders @ Stanley Center, Broad Institute
Reposted by Sameer Aryal
Reduction of SynGAP-γ, disrupted splicing of Agap3, and oligodendrocyte deficits in Srrm2 mice, a genetic model of schizophrenia and neurodevelopmental disorder https://www.biorxiv.org/content/10.1101/2024.10.10.617460v1
Reduction of SynGAP-γ, disrupted splicing of Agap3, and oligodendrocyte deficits in Srrm2 mice, a genetic model of schizophrenia and neurodevelopmental disorder https://www.biorxiv.org/content/10.1101/2024.10.10.617460v1
Rare loss-of-function (LoF) variants in SRRM2, which encodes the SRRM2 splicing factor, are associat
www.biorxiv.org
October 13, 2024 at 5:16 AM
Reduction of SynGAP-γ, disrupted splicing of Agap3, and oligodendrocyte deficits in Srrm2 mice, a genetic model of schizophrenia and neurodevelopmental disorder https://www.biorxiv.org/content/10.1101/2024.10.10.617460v1
Reposted by Sameer Aryal
Reduction of SynGAP-γ, disrupted splicing of Agap3, and oligodendrocyte deficits in Srrm2 mice, a genetic model of schizophrenia and neurodevelopmental disorder https://www.biorxiv.org/content/10.1101/2024.10.10.617460v1
Reduction of SynGAP-γ, disrupted splicing of Agap3, and oligodendrocyte deficits in Srrm2 mice, a genetic model of schizophrenia and neurodevelopmental disorder https://www.biorxiv.org/content/10.1101/2024.10.10.617460v1
Rare loss-of-function (LoF) variants in SRRM2, which encodes the SRRM2 splicing factor, are associat
www.biorxiv.org
October 13, 2024 at 5:16 AM
Reduction of SynGAP-γ, disrupted splicing of Agap3, and oligodendrocyte deficits in Srrm2 mice, a genetic model of schizophrenia and neurodevelopmental disorder https://www.biorxiv.org/content/10.1101/2024.10.10.617460v1
Reposted by Sameer Aryal
Tetanus on demand! (not for bioweapons, but for neuroscience research)
Tetanus toxin induces paralysis by using a protease to cleave VAMP2, a protein required for synaptic vesicle fusion and neurotransmitter release.
To harness this toxicity and use it as a beneficial tool for neuroscience,
Tetanus toxin induces paralysis by using a protease to cleave VAMP2, a protein required for synaptic vesicle fusion and neurotransmitter release.
To harness this toxicity and use it as a beneficial tool for neuroscience,
January 30, 2025 at 2:30 PM
Tetanus on demand! (not for bioweapons, but for neuroscience research)
Tetanus toxin induces paralysis by using a protease to cleave VAMP2, a protein required for synaptic vesicle fusion and neurotransmitter release.
To harness this toxicity and use it as a beneficial tool for neuroscience,
Tetanus toxin induces paralysis by using a protease to cleave VAMP2, a protein required for synaptic vesicle fusion and neurotransmitter release.
To harness this toxicity and use it as a beneficial tool for neuroscience,