Sam Feldstein
sam-feldstein.bsky.social
Sam Feldstein
@sam-feldstein.bsky.social
MD/PhD candidate at University of Illinois Chicago studying the effects of quorum sensing by Group A Strep on the host immune system | Movie/TV fanatic | Denver sports fan | Go 'Cats!
Excited to share my first first-author paper representing a portion of my PhD work in the Federle Lab. Long, frustrating, and not yielding an abundance of positive data like I had hoped, I'm proud that mbio and @asm.org saw its value

journals.asm.org/doi/10.1128/...
The Streptococcus pyogenes Rgg2/Rgg3 quorum sensing system causes global suppression of macrophage inflammatory programs via an intranuclear mechanism | mBio
Streptococcus pyogenes is a ubiquitous pathogen that causes over 600 million infections every year and 500,000 to 1 million fatalities. While in developed countries, it is generally known to cause mil...
journals.asm.org
September 29, 2025 at 2:34 PM
Somehow managed to successfully defend my PhD this week. Eternal thanks to Mike and the Federle Lab for getting me across the finish line with only minimal emotional damage. 3 quarters done—now back to med school.
March 27, 2025 at 8:27 PM
Reposted by Sam Feldstein
Hi all! I’m a postdoc in the Schmidt Lab at Northwestern University studying how light impacts physiology and behavior 👁️🐭. Excited to be on the job market this year and so happy share my recent preprints!!!

- www.biorxiv.org/content/10.1...
- www.biorxiv.org/content/10.1...
November 22, 2024 at 11:27 PM
From Timo: how often tackles are left on an island and how they do in such situations

Aka spot the Seahawks backup RTs
November 21, 2024 at 6:03 PM
Reposted by Sam Feldstein
Publication Alert! Happy to share our new work published in CellReports of a collaboration with the Zychlinsky Lab (Max Planck Institute for Infection Biology). "Histone H1 kills MRSA". cell.com/cell-reports.... Enjoy!
Histone H1 kills MRSA
Marsman et al. detect histone H1 in MRSA in human abscesses and demonstrate that it kills MRSA under physiological conditions. They identify through selective evolution and a genome-wide screen that h...
cell.com
November 15, 2024 at 12:28 PM