Saad Hannan
@saadhannan.bsky.social
Neuroscientist at Harvard studying GABA in ASD, epilepsy, Rett & Down syndromes. Instructor Neuro101V. Ex UCL & Intl. Rett Syndrome Foundation Fellow. Cricket at MCC, Putney CC & Cavaliers CC 🇬🇧🇧🇩🇺🇸
https://saadhannan.com
https://hannan.scholars.harvard.edu
https://saadhannan.com
https://hannan.scholars.harvard.edu
This was a large collaborative effort of many years spanning multiple continents and groups. Appreciate the help from everyone involved at @ucl.ac.uk , IoN, @crick.ac.uk , @blizardinstitute.bsky.social, University of Zagreb, @uottawa.ca and Chung-Ang University.
July 25, 2025 at 3:37 PM
This was a large collaborative effort of many years spanning multiple continents and groups. Appreciate the help from everyone involved at @ucl.ac.uk , IoN, @crick.ac.uk , @blizardinstitute.bsky.social, University of Zagreb, @uottawa.ca and Chung-Ang University.
For GABA circuit defects and gene dosage check out: www.biorxiv.org/content/10.1...
Hippocampal circuit-specific enhancement of GABA-inhibition caused by discrete gene regions in a Down syndrome model
Although Down syndrome (DS), trisomy 21, affects ~6 million people worldwide, the neural circuit mechanisms underlying the neurophenotypes of impaired learning, memory and language are unknown. A prom...
www.biorxiv.org
July 25, 2025 at 3:37 PM
For GABA circuit defects and gene dosage check out: www.biorxiv.org/content/10.1...
For early network defects and K channels visit: www.biorxiv.org/content/10.1...
Synaptic and intrinsic membrane defects disrupt early neural network dynamics in Down syndrome
Down syndrome, caused by trisomy 21, affects around six million people worldwide and features learning, memory and language deficits. However, the mechanisms underlying trisomy 21 neurophenotypes invo...
www.biorxiv.org
July 25, 2025 at 3:37 PM
For early network defects and K channels visit: www.biorxiv.org/content/10.1...
Same here. Thanks
November 24, 2024 at 10:03 PM
Same here. Thanks