Saad Hannan
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saadhannan.bsky.social
Saad Hannan
@saadhannan.bsky.social
Neuroscientist at Harvard studying GABA in ASD, epilepsy, Rett & Down syndromes. Instructor Neuro101V. Ex UCL & Intl. Rett Syndrome Foundation Fellow. Cricket at MCC, Putney CC & Cavaliers CC 🇬🇧🇧🇩🇺🇸

https://saadhannan.com
https://hannan.scholars.harvard.edu
Exciting news in Down syndrome research! Two preprints out (links below). We uncover a K⁺ channel defect during development & show elevated #GABA signaling is circuit-specific - offering insight into failed #Roche GABA trial. Targeting specific K⁺ channels & GABA circuits will be beneficial in DS
July 25, 2025 at 3:37 PM
This is sad news indeed. The way to make this count will be to learn from this every possible detail to help make the future safer for the others. Thoughts are with the family.
Sad news to report.

The Rett patient who was hospitalized with a critical immune reaction to $NGNE 's gene therapy has died.

A reminder that participants in these studies put themselves at risk in the hope for a cure not only for themselves but for others.

www.sec.gov/ix?doc=/Arch...
https://www.sec.gov/ix?doc=/Archives/edgar/data/1404644/000140464424000109/ngne-20241120.htm
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www.sec.gov
November 25, 2024 at 1:54 AM
Our website is now online. For details of our work on GABAergic neurobiology, pharmacology, disease mechanisms and tech development plus more please visit www.saadhannan.com
Saad Hannan
Neuroscientist and pharmacologist studying neural inhibition and diseases
www.saadhannan.com
November 24, 2024 at 10:24 PM