Raju Tomer
rtomer.bsky.social
Raju Tomer
@rtomer.bsky.social
Associate Prof. @ Columbia University
Sharing new work from us+collaborators. We take a step toward making organ-scale, subcellular 3D imaging as scalable & affordable as next-gen sequencing, to eventually fuel next-gen of AI-foundational models of tissues, organs. www.biorxiv.org/content/10.1...
Videos: www.youtube.com/playlist?lis...
Scalable, affordable, submicron 3D imaging of multi-centimeter scale samples. - YouTube
Hybrid Solid-Liquid Optics Enable Scalable, High-Resolution, Multi-Immersion Light-Sheet Microscopy. Authors: Cheng Gong, Pauline Affatato, Matt Fay, Sudha R...
www.youtube.com
November 4, 2025 at 6:05 PM
A milestone worth reflecting on - 1000 citations for our cleared tissue light sheet paper - the COLM.
Gratifying that core ideas have stood the test of time and are broadly adopted:
Cuvette-based sample mounting;
Virtual slit effect with rolling shutter CMOS;
and Linear adaptive offset correction!
October 3, 2025 at 9:02 PM
Love this!! I don’t think I’ve ever seen anything like this before -- high-res light sheet microscopes designated for use by individual researchers in one lab!! Fantastic to see real-world impact emerging, starting with Bianca’s lab at JLG, Columbia!
✨ Exciting news!

SLICE™, our award-winning light sheet microscope, is now up and running at the Marlin Lab at Columbia University @columbiauniversity.bsky.social, ready to power advanced 3D imaging and accelerate discovery.

Here’s to more breakthroughs ahead! 🚀🔬

#3DImaging #ResearchInnovation
August 28, 2025 at 12:37 AM
Reposted by Raju Tomer
We’re proud to work with Dr. Tomer & his team at Columbia University to bring SLICE to life, a compact, affordable light-sheet microscope making 3D imaging more accessible worldwide.

📖 magazine.columbia.edu/article/3d-i...

@rtomer.bsky.social @columbiauniversity.bsky.social

#SLICE #lightsheet
3D Imaging Just Got Easier
Columbia researchers have developed a powerful new microscope that could enable more scientists around the world to conduct cutting-edge biomedical research.
magazine.columbia.edu
May 5, 2025 at 3:30 PM
Reposted by Raju Tomer
We had to join the trend.

Introducing: Jack Glaser, Founder and President of MBF Bioscience —now an action figure. Complete with microscope, field journal, and trusty lab dog. 🧠🐕

In science, there are no small people—just big ideas.
#ScienceMatters #STEM #Microscopy
April 16, 2025 at 6:34 PM
Reposted by Raju Tomer
Our digital times :-)
March 20, 2025 at 1:33 PM
Reposted by Raju Tomer
Quite an essay on the basis of cancer entitled "The End of the Genetic Paradigm of Cancer" @plosbiology.org arguing against the primacy of somatic mutations (traditional model) and cells, invoking gene regulatory networks and tissue
journals.plos.org/plosbiology/...
March 18, 2025 at 6:25 PM
Reposted by Raju Tomer
have ppl found any funders that support toolmaking? I want to keep making tools for people, but there is a seemingly irresistible force pushing us towards hypothesis-driven research. In my experience, funders don't want to hear about tech dev. Any insights? for both neuro & climate would be great tx
December 19, 2024 at 11:32 PM
Reposted by Raju Tomer
Delighted to highlight our new paper in
@natureportfolio.bsky.social entitled 'Synaptic basis of feature selectivity in hippocampal neurons' (thread below 👇): www.nature.com/articles/s41...
Synaptic basis of feature selectivity in hippocampal neurons - Nature
A temporally asymmetric synaptic plasticity kernel results from bidirectional modifications of synaptic weights around the induction of a place field.
www.nature.com
December 18, 2024 at 10:00 PM