RSC Medicinal Chemistry
@rscmedchem.rsc.org
The journal for research and review articles in medicinal chemistry and related drug discovery science.
Published by @rsc.org 🌐 Website: rsc.li/rscmedchem
📢Our first issue of 2026 is now online!
🔓Check out the #OpenAccess article behind the cover by Naoko Yoshizawa-Sugata, Hisao Masai, Yoko Yamakoshi & co. @ethz.ch reporting new water-soluble cationic porphyrins with enhanced phototoxicity to cancer cell lines #medchem
pubs.rsc.org/en/content/a...
🔓Check out the #OpenAccess article behind the cover by Naoko Yoshizawa-Sugata, Hisao Masai, Yoko Yamakoshi & co. @ethz.ch reporting new water-soluble cationic porphyrins with enhanced phototoxicity to cancer cell lines #medchem
pubs.rsc.org/en/content/a...
January 28, 2026 at 3:10 PM
📢Our first issue of 2026 is now online!
🔓Check out the #OpenAccess article behind the cover by Naoko Yoshizawa-Sugata, Hisao Masai, Yoko Yamakoshi & co. @ethz.ch reporting new water-soluble cationic porphyrins with enhanced phototoxicity to cancer cell lines #medchem
pubs.rsc.org/en/content/a...
🔓Check out the #OpenAccess article behind the cover by Naoko Yoshizawa-Sugata, Hisao Masai, Yoko Yamakoshi & co. @ethz.ch reporting new water-soluble cationic porphyrins with enhanced phototoxicity to cancer cell lines #medchem
pubs.rsc.org/en/content/a...
Our inside front cover is work by Renato J. S. Oliveira, Dennis Russowsky & co on synthesising fluorescent dihydropyridine–dihydropyrimidinone hybrids and their inhibition of protein kinases for anticancer applications, take a look⬇️
pubs.rsc.org/en/content/a...
📍UFRGS and Barretos Cancer Hospital🧪
pubs.rsc.org/en/content/a...
📍UFRGS and Barretos Cancer Hospital🧪
December 12, 2025 at 2:01 PM
Our inside front cover is work by Renato J. S. Oliveira, Dennis Russowsky & co on synthesising fluorescent dihydropyridine–dihydropyrimidinone hybrids and their inhibition of protein kinases for anticancer applications, take a look⬇️
pubs.rsc.org/en/content/a...
📍UFRGS and Barretos Cancer Hospital🧪
pubs.rsc.org/en/content/a...
📍UFRGS and Barretos Cancer Hospital🧪
This month's front cover showcases a Review article by Paul Groundwater & co discussing structural qualities of β-lactamase enzymes and the efficacy of emerging β-lactamase inhibitors against clinically significant carbapenemases, read it here👀
pubs.rsc.org/en/content/a...
📍 @sydney.edu.au 🧪
pubs.rsc.org/en/content/a...
📍 @sydney.edu.au 🧪
December 12, 2025 at 10:00 AM
This month's front cover showcases a Review article by Paul Groundwater & co discussing structural qualities of β-lactamase enzymes and the efficacy of emerging β-lactamase inhibitors against clinically significant carbapenemases, read it here👀
pubs.rsc.org/en/content/a...
📍 @sydney.edu.au 🧪
pubs.rsc.org/en/content/a...
📍 @sydney.edu.au 🧪
December 11, 2025 at 1:32 PM
Recently added to the RSC Medicinal Chemistry Editor's Choice collection are Hayley Binch's chosen articles!
Be sure to read our blog to see what she chose and why 👉 blogs.rsc.org/md/2025/11/25/editors-choice-collection-hayley-binch
And scan the QR code to see our collection as it grows👀 🧪
Be sure to read our blog to see what she chose and why 👉 blogs.rsc.org/md/2025/11/25/editors-choice-collection-hayley-binch
And scan the QR code to see our collection as it grows👀 🧪
December 9, 2025 at 12:17 PM
Recently added to the RSC Medicinal Chemistry Editor's Choice collection are Hayley Binch's chosen articles!
Be sure to read our blog to see what she chose and why 👉 blogs.rsc.org/md/2025/11/25/editors-choice-collection-hayley-binch
And scan the QR code to see our collection as it grows👀 🧪
Be sure to read our blog to see what she chose and why 👉 blogs.rsc.org/md/2025/11/25/editors-choice-collection-hayley-binch
And scan the QR code to see our collection as it grows👀 🧪
2025 marks our journal's 5th Anniversary🎉
To celebrate, we have launched a collection aimed to highlight key advances in medicinal chemistry and drug discovery research in the last 5 years, as well as current breakthroughs and future prospects.
Read it here👉 pubs.rsc.org/en/journals/...
#chemsky🧪
To celebrate, we have launched a collection aimed to highlight key advances in medicinal chemistry and drug discovery research in the last 5 years, as well as current breakthroughs and future prospects.
Read it here👉 pubs.rsc.org/en/journals/...
#chemsky🧪
December 2, 2025 at 11:05 AM
2025 marks our journal's 5th Anniversary🎉
To celebrate, we have launched a collection aimed to highlight key advances in medicinal chemistry and drug discovery research in the last 5 years, as well as current breakthroughs and future prospects.
Read it here👉 pubs.rsc.org/en/journals/...
#chemsky🧪
To celebrate, we have launched a collection aimed to highlight key advances in medicinal chemistry and drug discovery research in the last 5 years, as well as current breakthroughs and future prospects.
Read it here👉 pubs.rsc.org/en/journals/...
#chemsky🧪
🔓On the inside front cover is #OpenAccess work by Oleg Mediannikov & Philipp Tsvetkov exploring the potential of repurposing FDA-approved microtubule-targeting agents (MTAs) in anti-amoebic therapy, take a look👀
pubs.rsc.org/en/content/a...
📍 @ird-fr.bsky.social, @univ-amu.fr 🧪
pubs.rsc.org/en/content/a...
📍 @ird-fr.bsky.social, @univ-amu.fr 🧪
November 17, 2025 at 10:01 AM
🔓On the inside front cover is #OpenAccess work by Oleg Mediannikov & Philipp Tsvetkov exploring the potential of repurposing FDA-approved microtubule-targeting agents (MTAs) in anti-amoebic therapy, take a look👀
pubs.rsc.org/en/content/a...
📍 @ird-fr.bsky.social, @univ-amu.fr 🧪
pubs.rsc.org/en/content/a...
📍 @ird-fr.bsky.social, @univ-amu.fr 🧪
🔓This month's front cover features an #OpenAccess Review article by David Morales-Morales and colleagues which discusses the antitumor properties of cyclometalated compounds containing metals from groups 8, 9, and 10, read it here⬇️
pubs.rsc.org/en/content/a...
📍UNAM, Mexico 🧪
pubs.rsc.org/en/content/a...
📍UNAM, Mexico 🧪
November 14, 2025 at 10:00 AM
🔓This month's front cover features an #OpenAccess Review article by David Morales-Morales and colleagues which discusses the antitumor properties of cyclometalated compounds containing metals from groups 8, 9, and 10, read it here⬇️
pubs.rsc.org/en/content/a...
📍UNAM, Mexico 🧪
pubs.rsc.org/en/content/a...
📍UNAM, Mexico 🧪
November 13, 2025 at 2:55 PM
Next up in the RSC Medicinal Chemistry Editor's Choice collection are Sally-Ann Poulsen's chosen articles!
Be sure to read our blog to see what she chose and why 👉 blogs.rsc.org/md/2025/11/1...
And scan the QR code to see our collection as it grows👀
Be sure to read our blog to see what she chose and why 👉 blogs.rsc.org/md/2025/11/1...
And scan the QR code to see our collection as it grows👀
November 11, 2025 at 11:01 AM
Next up in the RSC Medicinal Chemistry Editor's Choice collection are Sally-Ann Poulsen's chosen articles!
Be sure to read our blog to see what she chose and why 👉 blogs.rsc.org/md/2025/11/1...
And scan the QR code to see our collection as it grows👀
Be sure to read our blog to see what she chose and why 👉 blogs.rsc.org/md/2025/11/1...
And scan the QR code to see our collection as it grows👀
📢We are delighted to share our latest themed collection on Kinases, guest edited by Hayley Binch, @heppnerd.bsky.social, Meizhong Jin and Philip Jones!
Explore the articles that make up this fantastic collection, here👇
pubs.rsc.org/en/journals/...
#chemsky 🧪
Explore the articles that make up this fantastic collection, here👇
pubs.rsc.org/en/journals/...
#chemsky 🧪
October 29, 2025 at 2:05 PM
📢We are delighted to share our latest themed collection on Kinases, guest edited by Hayley Binch, @heppnerd.bsky.social, Meizhong Jin and Philip Jones!
Explore the articles that make up this fantastic collection, here👇
pubs.rsc.org/en/journals/...
#chemsky 🧪
Explore the articles that make up this fantastic collection, here👇
pubs.rsc.org/en/journals/...
#chemsky 🧪
Time is running out to nominate for the 2026 @rscmedchem.rsc.org Emerging Investigator Lectureship❗
⌛Make sure you make your nomination before 31 October 2025!
Find out how, here: www.rsc.org/standards-an...
#chemsky 🧪
⌛Make sure you make your nomination before 31 October 2025!
Find out how, here: www.rsc.org/standards-an...
#chemsky 🧪
October 28, 2025 at 2:15 PM
Time is running out to nominate for the 2026 @rscmedchem.rsc.org Emerging Investigator Lectureship❗
⌛Make sure you make your nomination before 31 October 2025!
Find out how, here: www.rsc.org/standards-an...
#chemsky 🧪
⌛Make sure you make your nomination before 31 October 2025!
Find out how, here: www.rsc.org/standards-an...
#chemsky 🧪
Have you submitted your nomination for the 2026 @rscmedchem.rsc.org Emerging Investigator Lectureship yet⁉️
It’s open to any early-stage researcher working independently in the field of medicinal chemistry.
More info here: www.rsc.org/standards-an...
Nominations close 31 October 2025⌛
🧪
It’s open to any early-stage researcher working independently in the field of medicinal chemistry.
More info here: www.rsc.org/standards-an...
Nominations close 31 October 2025⌛
🧪
October 23, 2025 at 10:45 AM
Have you submitted your nomination for the 2026 @rscmedchem.rsc.org Emerging Investigator Lectureship yet⁉️
It’s open to any early-stage researcher working independently in the field of medicinal chemistry.
More info here: www.rsc.org/standards-an...
Nominations close 31 October 2025⌛
🧪
It’s open to any early-stage researcher working independently in the field of medicinal chemistry.
More info here: www.rsc.org/standards-an...
Nominations close 31 October 2025⌛
🧪
On the front cover of issue 10 is work by Yosuke Demizu and colleagues on analysing the linker rigidity and improve intracellular behaviour of three novel PROTACs targeting H-PGDS, read more here👇
pubs.rsc.org/en/content/a...
📍National Institute of Health Sciences, Kanagawa 🧪
pubs.rsc.org/en/content/a...
📍National Institute of Health Sciences, Kanagawa 🧪
October 16, 2025 at 9:02 AM
On the front cover of issue 10 is work by Yosuke Demizu and colleagues on analysing the linker rigidity and improve intracellular behaviour of three novel PROTACs targeting H-PGDS, read more here👇
pubs.rsc.org/en/content/a...
📍National Institute of Health Sciences, Kanagawa 🧪
pubs.rsc.org/en/content/a...
📍National Institute of Health Sciences, Kanagawa 🧪
We are delighted to share our new collection: Highlights from Industry👀
Bringing together recent research and reviews by researchers in industry or as part of collaborations, we celebrate the innovations and discoveries from industry.
Explore the collection so far👉 pubs.rsc.org/en/journals/...
🧪
Bringing together recent research and reviews by researchers in industry or as part of collaborations, we celebrate the innovations and discoveries from industry.
Explore the collection so far👉 pubs.rsc.org/en/journals/...
🧪
October 15, 2025 at 1:46 PM
We are delighted to share our new collection: Highlights from Industry👀
Bringing together recent research and reviews by researchers in industry or as part of collaborations, we celebrate the innovations and discoveries from industry.
Explore the collection so far👉 pubs.rsc.org/en/journals/...
🧪
Bringing together recent research and reviews by researchers in industry or as part of collaborations, we celebrate the innovations and discoveries from industry.
Explore the collection so far👉 pubs.rsc.org/en/journals/...
🧪
📢Calling all medicinal chemistry researchers from academia and industry 📢
Nominations for the 2026 @rscmedchem.rsc.org Emerging Investigator Lectureship are open, and we’re excited to receive them!
Deadline to nominate is 31 October 2025 ⏰
More info here: www.rsc.org/standards-an...
#chemsky 🧪
Nominations for the 2026 @rscmedchem.rsc.org Emerging Investigator Lectureship are open, and we’re excited to receive them!
Deadline to nominate is 31 October 2025 ⏰
More info here: www.rsc.org/standards-an...
#chemsky 🧪
October 8, 2025 at 1:30 PM
📢Calling all medicinal chemistry researchers from academia and industry 📢
Nominations for the 2026 @rscmedchem.rsc.org Emerging Investigator Lectureship are open, and we’re excited to receive them!
Deadline to nominate is 31 October 2025 ⏰
More info here: www.rsc.org/standards-an...
#chemsky 🧪
Nominations for the 2026 @rscmedchem.rsc.org Emerging Investigator Lectureship are open, and we’re excited to receive them!
Deadline to nominate is 31 October 2025 ⏰
More info here: www.rsc.org/standards-an...
#chemsky 🧪
We are delighted to announce that Professor Christina Chai from National University of Singapore has joined the RSC Medicinal Chemistry Editorial Board as an Associate Editor🎉
Read our blog post to find out more about Christina 👉 rsc.li/4pJ88oR
#chemsky 🧪
Read our blog post to find out more about Christina 👉 rsc.li/4pJ88oR
#chemsky 🧪
September 30, 2025 at 9:26 AM
We are delighted to announce that Professor Christina Chai from National University of Singapore has joined the RSC Medicinal Chemistry Editorial Board as an Associate Editor🎉
Read our blog post to find out more about Christina 👉 rsc.li/4pJ88oR
#chemsky 🧪
Read our blog post to find out more about Christina 👉 rsc.li/4pJ88oR
#chemsky 🧪
Do you know an early career researcher working independently in the field of medicinal chemistry and drug discovery⁉
Why not nominate them for our 2026 Emerging Investigator Lectureship!
Nominations close 31 October 2025🚨
More details here: www.rsc.org/standards-an...
🧪
Why not nominate them for our 2026 Emerging Investigator Lectureship!
Nominations close 31 October 2025🚨
More details here: www.rsc.org/standards-an...
🧪
September 29, 2025 at 9:15 AM
Do you know an early career researcher working independently in the field of medicinal chemistry and drug discovery⁉
Why not nominate them for our 2026 Emerging Investigator Lectureship!
Nominations close 31 October 2025🚨
More details here: www.rsc.org/standards-an...
🧪
Why not nominate them for our 2026 Emerging Investigator Lectureship!
Nominations close 31 October 2025🚨
More details here: www.rsc.org/standards-an...
🧪
🔓The front cover of issue 9 is #OpenAccess work by Khondaker Miraz Rahman, Chris Pepper & co on a PBD-based PROTAC selectively degrading NF-κB subunit for RelA/p65-dependent tumour treatments, read it here👀
pubs.rsc.org/en/content/a...
📍 @kingscollegelondon.bsky.social, @bsmsmedschool.bsky.social🧪
pubs.rsc.org/en/content/a...
📍 @kingscollegelondon.bsky.social, @bsmsmedschool.bsky.social🧪
September 18, 2025 at 2:42 PM
🔓The front cover of issue 9 is #OpenAccess work by Khondaker Miraz Rahman, Chris Pepper & co on a PBD-based PROTAC selectively degrading NF-κB subunit for RelA/p65-dependent tumour treatments, read it here👀
pubs.rsc.org/en/content/a...
📍 @kingscollegelondon.bsky.social, @bsmsmedschool.bsky.social🧪
pubs.rsc.org/en/content/a...
📍 @kingscollegelondon.bsky.social, @bsmsmedschool.bsky.social🧪
In case you missed it: Nominations for the 2026 @rscmedchem.rsc.org Emerging Investigator Lectureship are now open👀
⌛Deadline for nominations is 31 October 2025!
Details about how to nominate are here: www.rsc.org/standards-an...
🧪
⌛Deadline for nominations is 31 October 2025!
Details about how to nominate are here: www.rsc.org/standards-an...
🧪
September 17, 2025 at 10:30 AM
In case you missed it: Nominations for the 2026 @rscmedchem.rsc.org Emerging Investigator Lectureship are now open👀
⌛Deadline for nominations is 31 October 2025!
Details about how to nominate are here: www.rsc.org/standards-an...
🧪
⌛Deadline for nominations is 31 October 2025!
Details about how to nominate are here: www.rsc.org/standards-an...
🧪
We’re excited to announce that nominations for our 2026 Emerging Investigator Lectureship are now open📢
Details about how to nominate: www.rsc.org/standards-an...
We’re looking for up-and-coming researchers in drug discovery within 12 yrs of their PhD.
Nominate before 31 October 2025!
#chemsky 🧪
Details about how to nominate: www.rsc.org/standards-an...
We’re looking for up-and-coming researchers in drug discovery within 12 yrs of their PhD.
Nominate before 31 October 2025!
#chemsky 🧪
September 4, 2025 at 1:04 PM
We’re excited to announce that nominations for our 2026 Emerging Investigator Lectureship are now open📢
Details about how to nominate: www.rsc.org/standards-an...
We’re looking for up-and-coming researchers in drug discovery within 12 yrs of their PhD.
Nominate before 31 October 2025!
#chemsky 🧪
Details about how to nominate: www.rsc.org/standards-an...
We’re looking for up-and-coming researchers in drug discovery within 12 yrs of their PhD.
Nominate before 31 October 2025!
#chemsky 🧪
📢Highlight your work on the cover of RSC Medicinal Chemistry!
We are looking for vibrant, eye-catching artwork to feature on our upcoming covers. Check out some of our previous covers and the benefits you receive for them👇
Interested in amplifying your research with a cover? Please let us know!
We are looking for vibrant, eye-catching artwork to feature on our upcoming covers. Check out some of our previous covers and the benefits you receive for them👇
Interested in amplifying your research with a cover? Please let us know!
August 27, 2025 at 10:45 AM
📢Highlight your work on the cover of RSC Medicinal Chemistry!
We are looking for vibrant, eye-catching artwork to feature on our upcoming covers. Check out some of our previous covers and the benefits you receive for them👇
Interested in amplifying your research with a cover? Please let us know!
We are looking for vibrant, eye-catching artwork to feature on our upcoming covers. Check out some of our previous covers and the benefits you receive for them👇
Interested in amplifying your research with a cover? Please let us know!
Next up in the RSC Medicinal Chemistry Editor's Choice collection are Cynthia Dowd's chosen articles!
Be sure to read our blog to see what she chose and why 👉 blogs.rsc.org/md/2025/08/2...
And scan the QR code to see our collection as it grows👀
Be sure to read our blog to see what she chose and why 👉 blogs.rsc.org/md/2025/08/2...
And scan the QR code to see our collection as it grows👀
August 26, 2025 at 1:44 PM
Next up in the RSC Medicinal Chemistry Editor's Choice collection are Cynthia Dowd's chosen articles!
Be sure to read our blog to see what she chose and why 👉 blogs.rsc.org/md/2025/08/2...
And scan the QR code to see our collection as it grows👀
Be sure to read our blog to see what she chose and why 👉 blogs.rsc.org/md/2025/08/2...
And scan the QR code to see our collection as it grows👀
This month's inside front cover features work by Partha Chakrabarti, Arindam Talukdar & co exploring a PROTAC-based strategy for the selective degradation of apoptosis signal-regulating kinase 1, towards targeted therapy in MASH. Take a look👀
pubs.rsc.org/en/content/a...
📍CSIR-IICB 🧪
pubs.rsc.org/en/content/a...
📍CSIR-IICB 🧪
August 18, 2025 at 8:31 AM
This month's inside front cover features work by Partha Chakrabarti, Arindam Talukdar & co exploring a PROTAC-based strategy for the selective degradation of apoptosis signal-regulating kinase 1, towards targeted therapy in MASH. Take a look👀
pubs.rsc.org/en/content/a...
📍CSIR-IICB 🧪
pubs.rsc.org/en/content/a...
📍CSIR-IICB 🧪
🔓On the front cover is #OpenAccess work by Sergii Afonin, Igor Komarov and colleagues on the in vitro evaluation of the immunogenic potential of gramicidin S and its photocontrolled analogues, read it here⬇️
pubs.rsc.org/en/content/a...
📍 @kit.edu and Taras Shevchenko National University of Kyiv 🧪
pubs.rsc.org/en/content/a...
📍 @kit.edu and Taras Shevchenko National University of Kyiv 🧪
August 15, 2025 at 9:00 AM
🔓On the front cover is #OpenAccess work by Sergii Afonin, Igor Komarov and colleagues on the in vitro evaluation of the immunogenic potential of gramicidin S and its photocontrolled analogues, read it here⬇️
pubs.rsc.org/en/content/a...
📍 @kit.edu and Taras Shevchenko National University of Kyiv 🧪
pubs.rsc.org/en/content/a...
📍 @kit.edu and Taras Shevchenko National University of Kyiv 🧪