Roland Calvert
rolandcalvert.bsky.social
Roland Calvert
@rolandcalvert.bsky.social
Reposted by Roland Calvert
Excited to share this new paper I helped with where we turned E. coli into tiny microlenses! Thread below. @meyerroc.bsky.social
@urochester.bsky.social
www.pnas.org/doi/10.1073/...
December 11, 2024 at 3:38 PM
Reposted by Roland Calvert
Excited to share my first-author preprint from the Knott Lab! Using de novo protein design, we developed anti-CRISPRs to potently inhibit CRISPR-Cas13. Thanks to my amazing co-authors !

www.biorxiv.org/content/10.1...

#CRISPR
De novo design of potent CRISPR-Cas13 inhibitors
CRISPR-Cas systems are transformative tools for gene editing which can be tuned or controlled by anti-CRISPRs (Acrs) - phage derived inhibitors that regulate CRISPR-Cas activity. However, Acrs that ar...
www.biorxiv.org
December 10, 2024 at 9:31 PM