Our postdoc @francdefel.bsky.social just gave a fantastic talk on gold-based artificial metalloenzymes for asymmetric catalysis. #Biotrans2025
@stratinghinst.bsky.social @rug.nl

#Biotrans2025 Gerard just gave an overview on recent advances in non-canonical amino acids application for novel artificial (metallo)enzymes from our group.

#RepArtZymes pre-conference in Basel also brought together some of our old and current group members.
@zhizhou1619.bsky.social @reubenlg.bsky.social

Our group members are attending #RepArtZymes Biotrans 2025 pre-conference. Gerard just presented our work on Artificial Metalloenzymes Featuring Thiol-Based Amino Acids. Compliments to the organisers #WardGroup for the fantastic program and a great get-together of the key players in our field.

Huge congratulations to our former PhD student Reuben @reubenlg.bsky.social on winning the KNCV-DCS Thesis Award from the Dutch Catalysis Society for his outstanding PhD research in our group! A well-deserved recognition of his hard work and dedication. 🎉

Tanja presented her work on metallaphotoredox catalysis in designer photoenzymes.
Congrats to both of you!
@stratinghinst.bsky.social @unigroningen.bsky.social

Our group members Tanja and Franco @francdefel.bsky.social presented their exciting research at NCCC this week.
Franco talked about his work on asymmetric catalysis in gold-based artificial metalloenzymes.

Our latest publication is out in @angewandtechemie.bsky.social!

We generated and engineered a novel artificial metalloenzyme for the enantioselective synthesis of a panel of γ-nitro-carbonyl compounds on a preparative scale.

Fantastic start of 2025 for the group. Our own Lars Longwitz won the @unigroningen.bsky.social FSE Postdoc prize for 2024. This prize celebrates his excellence in research and great potential of becoming a scientific leader. Well well deserved Lars! 👏

@stratinghinst.bsky.social

Season's greetings from Roelfes and Mayer groups! Wishing our colleagues, collaborators, and the entire community a joyful holiday season and a prosperous New Year ahead! 🎉🎄✨🧪

We characterised the corresponding thiophenol-based gold(I) enzyme with several techniques, including X-ray crystallography, that confirm the binding of the gold to the thiophenol and applied it in new-to-nature hydroamination reactions. doi.org/10.1002/anie...

We are thrilled to share our new noble-metal enzyme design approach. We used the in-vivo incorporation of a noble-metal-binding ligand for ArM design to bridge the versatility of noble metals with the catalytic power of enzymes.
Thread ⬇️

We are delighted to introduce our new Boron Designer Enzyme for the kinetic resolution of α-hydroxythioesters. For this activity, the noncanonical amino acid and a natural lysine residue have to work together to form a Hybrid Catalytic Dyad!