This work highlights how many ‘hidden’ microproteins remain to be discovered. uORFs aren’t just passive elements — they can encode regulators of metabolism and beyond. Excited to see where this field goes! 🍾

This work builds on our 2024 paper where we first described SLC35A4-MP. Here, we extend the story and uncover how this microprotein shapes mitochondrial biology and lipid metabolism in vivo.