Out today, our take on 6-methyladenine #6mA evolution in Eukaryotes @natgenet.nature.com. We asked a simple question, is really DNA 6mA common across the eukaryotes? The answer is "yes" if you're a unicellular eukaryote 🦠, not so if you're multicellular 🐝🌱🍄. www.nature.com/articles/s41... 1/9

Very happy to see our paper published online natcomms.nature.com. Thank you to @wellcometrust.bsky.social for funding this work during my time with @robklose.bsky.social and David Booth! Thanks also to collaborators @garcialabms.bsky.social @alexdemendoza.bsky.social and the other authors!

Happy to share the Biodiversity Cell Atlas white paper, out today in @nature.com. We look at the possibilities, challenges, and potential impacts of molecularly mapping cells across the tree of life.
www.nature.com/articles/s41...

't was lovely to host @julianolab.bsky.social here @uniofgalway.bsky.social. Great presentation and lots of fun later on a pint with @jgahan.bsky.social @rmacgabhann.bsky.social @hrhorkan.bsky.social and friends.

I am looking for a new postdoc to join the lab. Interested in pluripotency, germ cells, and in investigating these in a genetically tractable cnidarian? Get in touch! We offer a long-term contract, excellent research environment, and a lovely city #Galway. www.urifranklab.org

We are very excited to launch the registration for our 2025 symposium on 'Chromatin, Epigenetics and Transcription' today!

Join us at @tcddublin.bsky.social on May 28th for this event featuring keynote, new PI and PhD/postdoc talks and posters!

allirelandchromatinconsortium.ie/annual-meeti...

Happy to present the peer-reviewed version of our Hydractinia Cell Atlas paper out today in Nature Communications! As I presented this back when we were in “that other” social network, let me recap the basic findings and revision items in this thread:

www.nature.com/articles/s41...

The Hydractinia cell atlas is out. This remarkable animal has those cells, i-cells, that are pluripotent just like mammalian blastocyst inner cell mass. There is a difference, though––inner cell mass cells persist for only a few cell cycles before they differentiate; i-cells are adult cells.

New insight on gonad morphogenesis ! Our new paper reveals how germ & somatic cells interact through TGF-Beta feedback loop to drive gonad morphogenesis in Hydractinia.
Check out the full paper in Science Advances !

tinyurl.com/245rw699

#Hydractinia takes regeneration to the extreme¬in a new preprint, Curantz et al. show that dissociated, reaggregated cells can form a new individual. We also show how they do it and which cells types actually contribute to the new individual (tip: not many of them).
tinyurl.com/mr2s9zyf

Our final webinar before Christmas 🎅 is coming up!

We will be joined by Luciano Di Croce for his webinar on 'Dissecting Dynamics of Chromatin Function in Cell Differentiation and Cancer'.

Register here: us06web.zoom.us/webinar/regi...

@activemotifusa.bsky.social

SOX and POU are crucial Transcription Factors in animal development, believed to be innovations of this group. Here we find them in unicellular relatives of animals. And hold tight, you can use a choanoflagellate 🦠 SOX gene to make a full chimeric 🐁 ! Read more here 🧵: rdcu.be/d0dPN 1/6