🚨 New preprint out!
We reconstructed parental haplotypes in >440k individuals (UK & Estonian biobanks) to estimate assortative mating directly in the parental generation.
This reveals intensified assortment in recent generations.
www.biorxiv.org/content/10.1...

The paper comes with:
A Nature Research Briefing 🔗 www.nature.com/articles/d41...

Press releases from our local press:
🔗 www.unil.ch/news/fr/1754...
🔗 www.sib.swiss/fr/news/limp...

Open data & tools for the community :
🔗 rjhfmstr.github.io/THORIN/

🚨 Our parent-of-origin study is out in Nature! 🧬
Maternal and paternal alleles can have distinct — even opposite — effects on human traits, revealing a hidden layer of genetic architecture that standard GWAS miss.
🔗 www.nature.com/articles/s41...

Highlights below!

🎉 Hi #ESHG2025, the Statistical Genetics Group and alumni (@zkutalik.bsky.social) is coming in force!

Check out our latest work on human genetics!

📍Come see our talks & posters, or reach out to meet us!

🔬 How did we infer the parent-of-origin of alleles?
We developed a multi-step method leveraging:
IBD sharing with close relatives.
Chromosome X and mtDNA data for parental sides.
Crossover inference in siblings.
👉 Allowed us to assign parent-of-origin for ~221,000 individuals!