Riham Smoom
@riham-smoom.bsky.social
PhD in Genetics - Lab manager & Researcher at the Hebrew University of Jerusalem
Reposted by Riham Smoom
Another piece in the puzzle of telomere biology disorders and pulmonary fibrosis - well done to the Tzfati and @kaminskimed.bsky.social teams.
Beautiful paper!
#CureIPF
#MedSky
#SciSky
Beautiful paper!
#CureIPF
#MedSky
#SciSky
Wow!!
Mice inserted with RTEL1 point mutation causal of human Hoyeraal-Hreidarsson syndrome (HHS), display ⬆️ telomere DNA damage & fragility, aberrant hematopoiesis & pre-fibrotic changes in the lung.
Kudos Drs Smoom, Kaestner, Tzfati & team💪🏼
#ScienceMatters
academic.oup.com/nar/article/...
Mice inserted with RTEL1 point mutation causal of human Hoyeraal-Hreidarsson syndrome (HHS), display ⬆️ telomere DNA damage & fragility, aberrant hematopoiesis & pre-fibrotic changes in the lung.
Kudos Drs Smoom, Kaestner, Tzfati & team💪🏼
#ScienceMatters
academic.oup.com/nar/article/...
Separation of telomere protection from length regulation by two different point mutations at amino acid 492 of RTEL1
Abstract. RTEL1 is an essential DNA helicase that plays multiple roles in genome stability and telomere length regulation. The ultra-long telomeres of the
academic.oup.com
June 18, 2025 at 8:02 PM
Another piece in the puzzle of telomere biology disorders and pulmonary fibrosis - well done to the Tzfati and @kaminskimed.bsky.social teams.
Beautiful paper!
#CureIPF
#MedSky
#SciSky
Beautiful paper!
#CureIPF
#MedSky
#SciSky
Reposted by Riham Smoom
According to dogma mammalian telomeres shorten with age.
This paper shows that mouse telomeres do not shorten with age. Should we revisit the paradigm?
Kudos Drs Smoom, Tzfati & team!!!
#ScienceMattets
academic.oup.com/nar/article/...
This paper shows that mouse telomeres do not shorten with age. Should we revisit the paradigm?
Kudos Drs Smoom, Tzfati & team!!!
#ScienceMattets
academic.oup.com/nar/article/...
The house mouse maintains constant telomere length throughout life
Abstract. Telomeres protect the chromosome ends from deleterious DNA damage response and repair activities. In humans, telomerase maintains telomere length
academic.oup.com
August 30, 2025 at 10:54 PM
According to dogma mammalian telomeres shorten with age.
This paper shows that mouse telomeres do not shorten with age. Should we revisit the paradigm?
Kudos Drs Smoom, Tzfati & team!!!
#ScienceMattets
academic.oup.com/nar/article/...
This paper shows that mouse telomeres do not shorten with age. Should we revisit the paradigm?
Kudos Drs Smoom, Tzfati & team!!!
#ScienceMattets
academic.oup.com/nar/article/...
Do mouse telomeres shorten with age? 🐀
Our study, started in 2019, is now out in NAR! @narjournal.bsky.social 🎉
We show that house mouse telomeres stay stable with age — at least in blood and tail!
Thanks to Professors Tzfati & Kaestner and everyone who made this possible! 👇
doi.org/10.1093/nar/...
Our study, started in 2019, is now out in NAR! @narjournal.bsky.social 🎉
We show that house mouse telomeres stay stable with age — at least in blood and tail!
Thanks to Professors Tzfati & Kaestner and everyone who made this possible! 👇
doi.org/10.1093/nar/...
The house mouse maintains constant telomere length throughout life
Abstract. Telomeres protect the chromosome ends from deleterious DNA damage response and repair activities. In humans, telomerase maintains telomere length
doi.org
August 30, 2025 at 1:49 PM
Do mouse telomeres shorten with age? 🐀
Our study, started in 2019, is now out in NAR! @narjournal.bsky.social 🎉
We show that house mouse telomeres stay stable with age — at least in blood and tail!
Thanks to Professors Tzfati & Kaestner and everyone who made this possible! 👇
doi.org/10.1093/nar/...
Our study, started in 2019, is now out in NAR! @narjournal.bsky.social 🎉
We show that house mouse telomeres stay stable with age — at least in blood and tail!
Thanks to Professors Tzfati & Kaestner and everyone who made this possible! 👇
doi.org/10.1093/nar/...