Thrilled to share our latest review is now out in @cp-cellreports.bsky.social. Here, we explore the critical role of metabolism in shaping the outcomes of bacterial and viral respiratory infections.
www.cell.com/cell-reports...

I’m so excited to share that my paper on the role of itaconate in allergic airway disease and asthma has just been published in @allergy-eaaci.bsky.social!

You can read the paper here: onlinelibrary.wiley.com/doi/10.1111/...

#itaconate #allergy #asthma #immunometabolism #innateimmunity

Really pleased to see this study led by @raymondkiu.bsky.social now published in @natcomms.nature.com!

We show that probiotics help modulate the preterm infant 👶#microbiome - to reduce ARGs, lower MDR bacteria 🦠 & increase beneficial Bifido ✨

Huge team effort!

www.nature.com/articles/s41...

How does S. aureus turn a toxic metabolite into a survival tool? Rutgers-led research shows its enzyme FumC converts fumarate into fuel for growth, biofilm, & virulence—opening doors for new anti-pneumonia drugs. go.njmicrobe.org/8MQv9B #Microbiology #Pathogenesis #StaphAureus #AntimicrobialTargets

Grateful to be a co-author on the study showing how fumarate metabolism by host and pathogen promotes pneumonia. Itaconate synergises with fumarate and drives staphylococcal adaptation.👇

🚨New Preprint Alert!
Delighted to have been a small part of the study showing the role of fumarate metabolism in host and pathogen contributes to pneumonia infection.
Check out the link below to know more about #immunometabolites in promoting #S.aureus #pulmonary #adaptation.👇

Great work showcasing acetyl-CoA carboxylase 1 (ACC1) as a metabolic checkpoint in Treg biology. Increased acetyl-CoA levels drive increasing histone acetylation at the Foxp3. Under inflammatory conditions, fatty acid inhibition promotes the induction and long-term stability of Tregs.

c-kit and IL-17A-expressing ILC2s in sputum from individuals with severe asthma exhibit features of both ILC2s and ILC3s
www.science.org/doi/10.1126/...