Rick Zirkel
@rick-zirkel.bsky.social
Biomedical Engineering Postdoc @ Cornell University | Studying psychedelic drug action in vivo 🧠 🍄
More super important new science cautioning how we measure brain activity under the acute effects of psychedelics! Huge congrats to the authors!! 🧠🩸🍄🔬
🚨 New science alert! Our cross-species study, now in Nature Neuroscience, demonstrates psychedelics distort how we should interpret functional brain imaging.
👇🧵
nature.com/articles/s41...
#Neuroscience #Psychedelics #BrainImaging
👇🧵
nature.com/articles/s41...
#Neuroscience #Psychedelics #BrainImaging
Psychedelic 5-HT2A receptor agonism alters neurovascular coupling and differentially affects neuronal and hemodynamic measures of brain function
Nature Neuroscience - Padawer-Curry et al. show that the hallucinogenic 5-HT2A receptor agonist DOI alters neurovascular coupling in mice, with implications for the interpretation of human fMRI...
nature.com
October 16, 2025 at 7:21 PM
More super important new science cautioning how we measure brain activity under the acute effects of psychedelics! Huge congrats to the authors!! 🧠🩸🍄🔬
Reposted by Rick Zirkel
New preprint from collaboration with @sn-lab.bsky.social - 2p imaging of psilocybin's effects on neurovascular coupling 🧠🔬
We found that psilocybin prolongs the neurovascular response, independent of neural activity.
This would affect how we should interpret fMRI BOLD studies of psychedelics ‼️
We found that psilocybin prolongs the neurovascular response, independent of neural activity.
This would affect how we should interpret fMRI BOLD studies of psychedelics ‼️
Excited to share our latest work is up on bioRxiv! Looking at capillary flow speed changes we show that psilocybin prolongs the neurovascular coupling response to a visual stimulus. 🍄🔬🧠🩸
@chris-schaffer.bsky.social @alexkwan.bsky.social @sn-lab.bsky.social
Preprint:
www.biorxiv.org/content/10.1...
@chris-schaffer.bsky.social @alexkwan.bsky.social @sn-lab.bsky.social
Preprint:
www.biorxiv.org/content/10.1...
August 1, 2025 at 5:30 PM
New preprint from collaboration with @sn-lab.bsky.social - 2p imaging of psilocybin's effects on neurovascular coupling 🧠🔬
We found that psilocybin prolongs the neurovascular response, independent of neural activity.
This would affect how we should interpret fMRI BOLD studies of psychedelics ‼️
We found that psilocybin prolongs the neurovascular response, independent of neural activity.
This would affect how we should interpret fMRI BOLD studies of psychedelics ‼️
Excited to share our latest work is up on bioRxiv! Looking at capillary flow speed changes we show that psilocybin prolongs the neurovascular coupling response to a visual stimulus. 🍄🔬🧠🩸
@chris-schaffer.bsky.social @alexkwan.bsky.social @sn-lab.bsky.social
Preprint:
www.biorxiv.org/content/10.1...
@chris-schaffer.bsky.social @alexkwan.bsky.social @sn-lab.bsky.social
Preprint:
www.biorxiv.org/content/10.1...
August 1, 2025 at 5:06 PM
Excited to share our latest work is up on bioRxiv! Looking at capillary flow speed changes we show that psilocybin prolongs the neurovascular coupling response to a visual stimulus. 🍄🔬🧠🩸
@chris-schaffer.bsky.social @alexkwan.bsky.social @sn-lab.bsky.social
Preprint:
www.biorxiv.org/content/10.1...
@chris-schaffer.bsky.social @alexkwan.bsky.social @sn-lab.bsky.social
Preprint:
www.biorxiv.org/content/10.1...
Reposted by Rick Zirkel
Our paper on MouseGoggles - an open-source mini VR headset for mice - just came out! Really excited about finally integrating eye-tracking into the headset. Nice working with you @hongyuchang.bsky.social!
www.nature.com/articles/s41...
github.com/sn-lab/Mouse...
#neuroskyence
www.nature.com/articles/s41...
github.com/sn-lab/Mouse...
#neuroskyence
December 12, 2024 at 2:05 PM
Our paper on MouseGoggles - an open-source mini VR headset for mice - just came out! Really excited about finally integrating eye-tracking into the headset. Nice working with you @hongyuchang.bsky.social!
www.nature.com/articles/s41...
github.com/sn-lab/Mouse...
#neuroskyence
www.nature.com/articles/s41...
github.com/sn-lab/Mouse...
#neuroskyence