Roberto Giovannoni
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rgiovannoni.bsky.social
Roberto Giovannoni
@rgiovannoni.bsky.social
Associate Professor of Genetics at University of Pisa. 🇪🇺 European citizen living in Italy. In love with #teaching and #science. Interested in #biotechnology, #AI, #genetics, #genomics
Reposted by Roberto Giovannoni
This is awesome! Lipid probes for quantitative imaging of lipid transport. A real need in the lipid field!

@nadlerlab.bsky.social
Quantitative imaging of lipid transport in mammalian cells - Nature
Directional, non-vesicular lipid transport is responsible for fast, species-selective lipid sorting into organelle membranes.
www.nature.com
August 27, 2025 at 11:34 AM
Reposted by Roberto Giovannoni
First real-time human embryo implantation recorded (in 2D and 3D). Time lapse video of 2 embryos (200 μm apart) implanting in the 3D platform
science.org/doi/10.1126/...
August 15, 2025 at 7:39 PM
Reposted by Roberto Giovannoni
PyVADesign: a Python-based cloning tool for one-step generation of large mutant libraries www.biorxiv.org/content/10.1... 🧬🖥️🧪 github.com/CDDLeiden/Py...
May 9, 2025 at 8:02 PM
Reposted by Roberto Giovannoni
"Despite the narratives currently rampaging in the United States that people of color are 'DEI hires' lacking merit, I am finally confident in my abilities as a scientist. However, perseverance can only take me so far." #ScienceWorkingLife scim.ag/4jbwsff
April 21, 2025 at 2:07 PM
Reposted by Roberto Giovannoni
We are witnessing the destruction of science in America | Paul Darren Bieniasz www.theguardian.com/commentisfre...
We are witnessing the destruction of science in America | Paul Darren Bieniasz
If we stay on this administration’s course, future life-saving medicines may never be invented
www.theguardian.com
April 10, 2025 at 5:06 AM
Reposted by Roberto Giovannoni
How to accurately genotype SV is important & we discovered a huge bias in other methods!

Many improvements across population wide SV calling!

Out now Kanpig: nature.com/articles/s41...
@naturecomms.bsky.social
Great work from Adam E @bcmhouston.bsky.social
with help from @broadinstitute.org
K-mer analysis of long-read alignment pileups for structural variant genotyping - Nature Communications
Accurately genotyping structural variant (SV) alleles is crucial to genomics research. Here the authors present a rapid and accurate method that avoids common errors seen with other genotypers, partic...
nature.com
April 9, 2025 at 12:39 PM
Reposted by Roberto Giovannoni
Professional gene editor and professor of Genetics here.
The world does not need more negativity. It does not need more nonscientific hype, either. I will be data-based negative and say to Colossal: give me a double-strand break!! [1/3]
April 8, 2025 at 10:50 PM
Reposted by Roberto Giovannoni
Dietary omega-6 linoleic acid signals via FABP5-mTORC1! FABP5 binds Raptor, revealing new lipid sensing. 🍽️🧬 #NutritionScience PMID:40080571, Science 2025, @ScienceMagazine https://doi.org/10.1126/science.adm9805 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
https://doi.org/10.1126/science.adm9805
No description available
doi.org
April 3, 2025 at 11:10 AM
Reposted by Roberto Giovannoni
If you need to sample reads (with or without replacement) from FASTQ files you may find the fastQpick utility by Joseph Rich super useful: github.com/pachterlab/f...
GitHub - pachterlab/fastQpick
Contribute to pachterlab/fastQpick development by creating an account on GitHub.
github.com
January 27, 2025 at 1:11 AM