Rob Beagrie
@rbeagrie.bsky.social
Group leader and Wellcome Sir Henry Dale Fellow based at the Centre for Human Genetics at Oxford University. Interested in genomics, single-cell technologies, 3D DNA folding and chromatin disruption in human disease. He/him.
Most people I know are doing PE150 because it almost always ends up cheaper if you’re outsourcing. But I’d be interested to know how much fragment size affect mappability. Presumably the larger the fragment the better the chances of at least one end having a unique alignment?
August 1, 2025 at 8:08 PM
Most people I know are doing PE150 because it almost always ends up cheaper if you’re outsourcing. But I’d be interested to know how much fragment size affect mappability. Presumably the larger the fragment the better the chances of at least one end having a unique alignment?