Raquel Castelo Branco
@raquelcbranco.bsky.social
PostDoc at Leão lab, CIIMAR, Pt
Cyanobacteria, natural products, enzymes and biosynthesis
Cyanobacteria, natural products, enzymes and biosynthesis
Reposted by Raquel Castelo Branco
Check out our group’s just-published paper in @NatureCommun: a macrocyclase with a built-in kinase domain that can phosphorylate peptides during RiPP biosynthesis and be swapped into other pathways 🧬
@ciimar.bsky.social @BlueBio4Future
www.nature.com/articles/s41...
@ciimar.bsky.social @BlueBio4Future
www.nature.com/articles/s41...
Phosphorylation of peptides by a kinase domain in cyanobactin pathways - Nature Communications
Phosphorylation is a key protein modification but rare in natural product biosynthesis. Here, authors discover cyanobacterial pathways that encode a kinase domain, leading to the production of phospho...
www.nature.com
November 24, 2025 at 9:45 AM
Check out our group’s just-published paper in @NatureCommun: a macrocyclase with a built-in kinase domain that can phosphorylate peptides during RiPP biosynthesis and be swapped into other pathways 🧬
@ciimar.bsky.social @BlueBio4Future
www.nature.com/articles/s41...
@ciimar.bsky.social @BlueBio4Future
www.nature.com/articles/s41...
Reposted by Raquel Castelo Branco
Oral abstract submission is now open for Directing Biosynthesis VIII, an event that has been connecting #Biosynthesis researchers for over a decade.
Network and discuss the latest research, get all the details and submit: rsc.li/dbviii
#DBVIII #ChemSky
Network and discuss the latest research, get all the details and submit: rsc.li/dbviii
#DBVIII #ChemSky
November 17, 2025 at 3:51 PM
Oral abstract submission is now open for Directing Biosynthesis VIII, an event that has been connecting #Biosynthesis researchers for over a decade.
Network and discuss the latest research, get all the details and submit: rsc.li/dbviii
#DBVIII #ChemSky
Network and discuss the latest research, get all the details and submit: rsc.li/dbviii
#DBVIII #ChemSky
Reposted by Raquel Castelo Branco
Genome-informed Discovery of Monchicamides A–K: Cyanobactins from the Microcoleaceae Cyanobacterium LEGE 16532 | Journal of Natural Products pubs.acs.org/doi/10.1021/...
Genome-informed Discovery of Monchicamides A–K: Cyanobactins from the Microcoleaceae Cyanobacterium LEGE 16532
Genome mining has emerged as an important tool for the discovery of natural products and is particularly effective for the swift identification of ribosomally synthesized and post-translationally modi...
pubs.acs.org
December 27, 2024 at 4:33 PM
Genome-informed Discovery of Monchicamides A–K: Cyanobactins from the Microcoleaceae Cyanobacterium LEGE 16532 | Journal of Natural Products pubs.acs.org/doi/10.1021/...
Reposted by Raquel Castelo Branco
Are you working on natural products? We’ve just released version 4.0 of the MIBiG data standard and repository! It now includes 3059 biosynthetic gene clusters, thanks to the combined efforts of 288 expert contributors. A thread: (1/8) academic.oup.com/nar/advance-...
MIBiG 4.0: advancing biosynthetic gene cluster curation through global collaboration
Abstract. Specialized or secondary metabolites are small molecules of biological origin, often showing potent biological activities with applications in ag
academic.oup.com
December 10, 2024 at 8:05 AM
Are you working on natural products? We’ve just released version 4.0 of the MIBiG data standard and repository! It now includes 3059 biosynthetic gene clusters, thanks to the combined efforts of 288 expert contributors. A thread: (1/8) academic.oup.com/nar/advance-...