Raphael Onuku
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raphaelonuku.bsky.social
Raphael Onuku
@raphaelonuku.bsky.social
PhD Candidate (Medicinal Chemistry) @ University of Michigan | MOE Taiwan Government Scholar & Top Graduate @ Taipei Medical University
hopping (software and programs) and organopalladium catalysis leveraged for the synthesis of templates designed via scaffold hopping.

5/5
November 14, 2024 at 3:37 PM
complete structural overhauls were the strategies employed by the medicinal chemist to generate a library of bifunctional inhibitors. In addition, the review presents an overview of the computational methods of scaffold…..

4/5
November 14, 2024 at 3:37 PM
In this review, we present the scaffold hopping-based drug design strategies for dual inhibitory antitumor structural templates. Minor modifications, structure rigidification and simplification (ring-closing and opening), and….

3/5
November 14, 2024 at 3:37 PM
An integrated approach involving computational advancements, synthetic methodology advancements, and conventional drug design strategies is required to increase the number of scaffold-hopping-assisted drug discovery campaigns.

#scaffoldhopping #compchem

2/5
November 14, 2024 at 3:37 PM
I’m curious. Please, how did you do it?
November 9, 2024 at 11:01 PM
How do people get invited by the way? I mean... What's the rational requirement after submitting the form?
July 10, 2023 at 6:46 AM
What is happening to Musk? 😮‍💨
July 10, 2023 at 6:43 AM
that's so sad 😔
July 10, 2023 at 6:42 AM
Marvel heroes, on the other hand, offer a nuanced perspective on varying issues, such as ethical use of technology or societal acceptance. They represent different facets of the American mythos. Rather than ranking them, we should appreciate the cultural richness they bring.
July 10, 2023 at 6:41 AM
Comparing Superman and Marvel heroes isn't a matter of 'better,' but a reflection of diverse narratives. Superman, as a pioneer, embodies hope and quintessential American values.
July 10, 2023 at 6:40 AM