Rodrigo Morales Castro
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ramoralescastro.bsky.social
Rodrigo Morales Castro
@ramoralescastro.bsky.social
Researcher at Karolinska Institutet @ki.se. Working on #zebrafish models of #inflammation and #regeneration
Infinite thanks to @ejvillablanca.bsky.social and all the co-authors Bianca Kern, @angiedb.bsky.social, Eveline Meinen, Danxia Zhao, Yuqing Zhou, Francisca Castillo, @gamonasterioo.bsky.social, Vlad Farcas, Myra Chávez and Jennifer Fransson who make this work possible!! 🥳
May 14, 2025 at 9:47 AM
Also, we found that our generated model of injury shares transcriptional features with IBD patients, which opens the possibility for future translational studies!
May 14, 2025 at 9:42 AM
Our main findings are:

- We showed that macrophages accumulated in the regenerating intestine and promoted proliferation of intestinal cells.
- We identified igfbp1a as a novel regulator of intestinal regeneration, promoting the closure and proliferation of the intestinal barrier.
May 14, 2025 at 9:37 AM