Raghu
@raghuv.bsky.social
Structural Biology | Dynamics | Virology | Infectious diseases| Molecular modelling | Phenomenology
Forms and functions
Forms and functions
Our latest work in Cell Reports Physical Science,
We engineered dengue virus-like particles with enhanced secretion & stability — advancing next-gen VLP-based dengue vaccine development.
#Dengue #VaccineDesign #VirusLikeParticles
www.cell.com/cell-reports...
We engineered dengue virus-like particles with enhanced secretion & stability — advancing next-gen VLP-based dengue vaccine development.
#Dengue #VaccineDesign #VirusLikeParticles
www.cell.com/cell-reports...
An integrative approach to rational engineering of dengue virus-like particles
Using multiscale simulations and experimental validation, this study uncovers how
envelope protein-lipid interactions govern dengue virus-like particle (VLP) stability,
secretion, and immunogenicity. ...
www.cell.com
September 11, 2025 at 3:11 AM
Our latest work in Cell Reports Physical Science,
We engineered dengue virus-like particles with enhanced secretion & stability — advancing next-gen VLP-based dengue vaccine development.
#Dengue #VaccineDesign #VirusLikeParticles
www.cell.com/cell-reports...
We engineered dengue virus-like particles with enhanced secretion & stability — advancing next-gen VLP-based dengue vaccine development.
#Dengue #VaccineDesign #VirusLikeParticles
www.cell.com/cell-reports...
In our latest work on dengue virus (DENV) nucleocapsid assembly, we combine single-molecule FRET and molecular dynamics simulations to reveal mechanistic insights into the RNA chaperone activity of the DENV Capsid (C) protein.
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Structural flexibility in the ordered domain of the dengue virus strain 2 capsid protein is critical for chaperoning viral RNA replication - Cellular and Molecular Life Sciences
Viral replication necessitates intricate nucleic acid rearrangements, including annealing and strand displacement to achieve the viral RNA functional structure. Often a single RNA chaperone performs t...
link.springer.com
April 29, 2025 at 1:40 AM
In our latest work on dengue virus (DENV) nucleocapsid assembly, we combine single-molecule FRET and molecular dynamics simulations to reveal mechanistic insights into the RNA chaperone activity of the DENV Capsid (C) protein.
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Reposted by Raghu
My latest column in EMBO Reports @emboreports.org , co-authored with Will Ratcliff @wcratcliff.bsky.social : "Using AI to prepare for academic interviews – don’t trade authenticity for polish." www.embopress.org/doi/full/10....
Using AI to prepare for academic interviews – don’t trade authenticity for polish | EMBO reports
EMBO Press is an editorially independent publishing platform for the development of EMBO scientific publications.
www.embopress.org
February 18, 2025 at 9:44 PM
My latest column in EMBO Reports @emboreports.org , co-authored with Will Ratcliff @wcratcliff.bsky.social : "Using AI to prepare for academic interviews – don’t trade authenticity for polish." www.embopress.org/doi/full/10....
Reposted by Raghu
Destroy this myth. Please share if you have visited and researched in a library this past year! RT And give a shout out to your favorite library you have ever visited.
December 21, 2024 at 12:49 AM
Destroy this myth. Please share if you have visited and researched in a library this past year! RT And give a shout out to your favorite library you have ever visited.