Radcliff Huffman
radcliffth.bsky.social
Radcliff Huffman
@radcliffth.bsky.social
PhD Candidate at UC Santa Cruz - Natural Products, Chemical Biology, Enzymology, and Neuroscience
Reposted by Radcliff Huffman
Check out our ibogaine total synthesis in @NatureChemistry! This was a tough project that took nearly a decade to complete by @UCDavisIPN researchers.
Includes the synthesis of the unnatural enantiomer of ibogaine and ibogaine analogues that modulate SERT

www.nature.com/articles/s41...
Efficient and modular synthesis of ibogaine and related alkaloids - Nature Chemistry
Preliminary clinical trials suggest that ibogaine and its active metabolite noribogaine have powerful anti-addictive properties, Now, a strategy for the scalable, asymmetric total synthesis of ibogain...
www.nature.com
February 8, 2025 at 2:30 PM