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prostateukprofs.bsky.social
Prostate Cancer UK Professionals
@prostateukprofs.bsky.social
270 followers 440 following 230 posts
Here we share news and views from @ProstateCancerUK for our growing professional community who have an interest in prostate disease 🧑‍🔬⤵️
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prostateukprofs.bsky.social
Could CAR-T cells carrying collagen targeted IL-12 be a safe therapy for #ProstateCancer?

A team including Prostate Cancer UK fellow @Ko1ssk.bsky.social & Jun Ishihara @imperialcollegeldn.bsky.social share new results in @natbiomedeng.nature.com.

Grab a ☕ and read:
doi.org/10.1038/s415...
November 11, 2025 at 5:01 PM
prostateukprofs.bsky.social
📢Careers in Research Webinar📢

🤔Got a great idea, but not sure how to turn it into a clinical trial?

📉Curious about careers in trials – stats, methods, data?

Register to explore how partnering with a CTSU can support researchers at every stage 👇

events.teams.microsoft.com/event/2b9a0b...
Careers in Research Webinar. Clinical Trials Units: Elevating Research for Real-World Impact. Tuesday 13 January 2026, 1-2pm (online). Professor Emma Hall and Claire Snowdon. The Institute of Cancer Research - Clinical Trials and Statistics Unit (ICR-CTSU).
November 11, 2025 at 10:14 AM
prostateukprofs.bsky.social
Calling all Clinician and AHPs 👨‍⚕️ 👩‍⚕️

Apply for our free 18-month flagship Clinical Champions Programme. Become a leader in transforming care and support for men impacted by prostate cancer.

Apply today 👉 bit.ly/46I5Fn9
November 10, 2025 at 9:02 PM
prostateukprofs.bsky.social
Our new Black Men’s One-to-One Support Service connects Black men affected by prostate cancer to a volunteer who truly understands their experience.

🩵 Please signpost men in your care to bit.ly/47yAMke or our phone line 0800 448 0745 to self-refer.
Man in a white shirt wearing a Prostate Cancer UK pin badge, speaking on a phone, with text 'Our new Black Men's One-to-One Support Service'.
November 5, 2025 at 7:01 AM
prostateukprofs.bsky.social
Could genetic information help personalise radiotherapy to reduce rectal toxicity?

A team led by Dr Alan McWilliam and Artemis Bouzaki at @manchester.ac.uk report exciting new findings in Clinical Cancer Research.

Grab a ☕ and read: doi.org/10.1158/1078...
Scientific Paper published in Clinical Cancer Research, titled: Integration of Dose Surface Maps and Genetic Data Identifies the Lower Posterior Rectum as a Key Region for Toxicity after Prostate Cancer Radiotherapy. Written by Bouzaki et al.
November 4, 2025 at 5:04 PM
prostateukprofs.bsky.social
Next CRSG meeting:
📅Fri 17 Apr 2026,
🚩London.

Details 👇
🔗 prostatecanceruk.org/research/for...
Members of the Clinical Research Strategy Group at the Prostate Cancer UK headquarters
October 31, 2025 at 7:03 PM
prostateukprofs.bsky.social
🧵[1/6]

📣 Big news for clinical prostate cancer researchers!

The NCRI Prostate Group has re-established as UK Prostate Cancer Clinical Research Strategy Group (CRSG) - a national hub for collaboration & innovation in prostate cancer research.

Learn more 👇
prostatecanceruk.org/research/for...
October 31, 2025 at 7:00 PM
prostateukprofs.bsky.social
🎵 Movin’ for Men’s Health! One of our brilliant researchers, Prof. Charlotte Bevan, is hosting a Soul Nite to raise funds for @prostateuk.bsky.social and Movember.

📅 When: 8pm, 8th November
📍 Where: The Camden Club, London

Find out more and register ⤵️
buff.ly/vidaQg8
October 31, 2025 at 4:00 PM
prostateukprofs.bsky.social
Last month, we launched our new One-to-One support service for Black men, which operates alongside our existing peer support service.

Please signpost Black men in your care to bit.ly/47yAMke or our phone line 0800 448 0745 to self-refer. 💙
Man in a white shirt wearing a Prostate Cancer UK pin badge, speaking on a phone, with text 'Our new Black Men's One-to-One Support Service'.
October 31, 2025 at 3:57 PM
prostateukprofs.bsky.social
🗣️ Just 1 week left to share your views on the 10-year NHS England workforce plan!

Share your views on:
🔜Future NHS workforce models
📋How to support delivery of the 3-shifts
🥼How to align staff with the future of the NHS in England

📅Due 7 Nov

buff.ly/DuyIVqU
Three healthcare professionals, one in a nurse uniform, discuss documents in a hospital setting.
October 31, 2025 at 10:23 AM
prostateukprofs.bsky.social
Could radiomic features guide adaptive radiotherapy to minimise rectal toxicity?

A brilliant team led by Prof. Bill Nailon, Prof. Duncan McLaren and Dr Zhuolin Yang at @uni-of-edinburgh.bsky.social share interesting new findings in phiRO.

Grab a ☕ and read: doi.org/10.1016/j.ph...
Scientific Paper Published in Physics and Imaging in Radiation Oncology, titled: Identifying the optimal time point for adaptive re-planning in prostate cancer radiotherapy to minimise rectal toxicity using normal tissue imaging biomarkers. Written by Yang et al.
October 28, 2025 at 5:02 PM
prostateukprofs.bsky.social
📣Each From Ideas to Innovation session will feature a reflection by a Patient Research Partner (PRP) -a man or family member affected by #ProstateCancer.

🙏We’re grateful to our PRPs for sharing their stories & shaping our research.

⬇️ Register to attend.
prostatecanceruk.org/research/for...
From Ideas to Innovation will unite clinicians, scientists, Prostate Cancer UK, and patient representatives in their tireless collaboration to light the path to progress and hope. Dr Ning Wang, University of Leicester.
October 28, 2025 at 8:02 AM
prostateukprofs.bsky.social
🗣️ Hear from experts sharing the latest data on the use of genetic information in prostate cancer care at the high-profile conference, Genomics and Prostate Cancer.

📅 Friday 12 December
📍 The Royal Society of Medicine, London
➡️ Secure your place: bit.ly/4pS5cGz
Conference Titled: Genomics and prostate cancer - the latest in patient care. The meeting takes place on Friday 12 December 2025, 9.00am-4.30pm.
October 27, 2025 at 4:30 PM
prostateukprofs.bsky.social
There’s still time to share your thoughts on the 10-year NHS England workforce plan!

Share your views on:
🔜Future NHS workforce models
📋How to support delivery of the 3-shifts
🥼How to align staff with the future of the NHS in England

📅Due 7 Nov

buff.ly/DuyIVqU
Three healthcare professionals, one in a nurse uniform, discuss documents in a hospital setting.
October 26, 2025 at 8:59 PM
prostateukprofs.bsky.social
The October edition of Research News is here! Read more about:

🚴 Tour de 4.
🤝 Upcoming meetings and webinars.
🌱 A personal development resource.
🗣️ Speakers at our researcher event, From Ideas to Innovation.
💰 Funding opportunities.

📖 Read it here: prostatecanceruk.org/research/for...
Picture of Prostate Cancer UK volunteer team at Tour de 4.
October 24, 2025 at 10:01 AM
prostateukprofs.bsky.social
[9/9] 📖 If you would like to learn more about why this research is so important for men with #ProstateCancer, you can read more about the project in our latest News & Views article: buff.ly/3QrafUP
Prostate Cancer UK icon of a man having an MRI scan.
October 23, 2025 at 2:37 PM
prostateukprofs.bsky.social
[8/9] Impact:

🥳 bpMRI detects clinically significant #ProstateCancer as effectively as mpMRI, without increasing detection of insignificant cancer.

💙 Adopting bpMRI scans would increase scanner capacity and help more men receive timely diagnoses.
A smiling man with lived experience spending time with his family, appearing happy and relaxed.
October 23, 2025 at 2:37 PM
prostateukprofs.bsky.social
[7/9] ✅ Importantly, the team also demonstrated that bpMRI and mpMRI detect a comparable number of clinically insignificant #ProstateCancer.

💙 This is crucial to minimise overdiagnosis and protect men from unnecessary biopsies.
Table showing that bpMRI and mpMRI detect a comparable number of clinically insignificant prostate cancer, with the difference in detection between the two methods being only −0.4%.
October 23, 2025 at 2:37 PM
prostateukprofs.bsky.social
[6/9] ✅ Excitingly, the research showed that bpMRI is just as effective as mpMRI in detecting clinically significant #ProstateCancer.
Graph showing that mpMRI detected slightly more clinically significant prostate cancer than bpMRI. Yet, the difference in detection between the two methods was only −0.4% and not statistically significant
October 23, 2025 at 2:36 PM
prostateukprofs.bsky.social
[5/9] 👨 In the trial, 490 men underwent a scan.

🩻 Results for bpMRI were reviewed first, followed by those for mpMRI.

💉 If either scan indicated #ProstateCancer, men had a targeted biopsy.
Diagram showing flow of participants in the PRIME Trial.
October 23, 2025 at 2:36 PM
prostateukprofs.bsky.social
[4/9] 💰 To explore this, we funded a clinical trial called PRIME, which investigated whether bpMRI is as effective as mpMRI in detecting clinically significant #ProstateCancer.
Quote from Associate Professor Veeru Kasivisvanathan, PRIME trial Lead Researcher and Chief Investigator: "If we can do the scan in up to half the time, with fewer staff and at a lower cost, that will make a huge difference in allowing every man who needs a scan to be able to get one in a timely fashion."
October 23, 2025 at 2:36 PM
prostateukprofs.bsky.social
[3/9] 💡 The team proposed biparametric MRI (bpMRI) as a faster, effective alternative.

🩻 While mpMRI uses 3 imaging types, bpMRI uses 2 and doesn’t require contrast agents, cutting scan time by up to 50%, increasing capacity, removing the need for injections, and lowering costs.
Advantages of biparametric MRI compared to multiparametric MRI include: - Shorter Scans. - Injection-free. - Lower Cost. - No medical practitioner required, as no contrast agent needed. - Absence of contrast agent reduces environmental impact.
October 23, 2025 at 2:36 PM
prostateukprofs.bsky.social
[2/9] ️Multiparametric MRI (mpMRI) is now a key part of the diagnostic pathway for #ProstateCancer, thanks in part to research we supported in 2008.

👨 The next challenge: how can we make diagnostic imaging more efficient?
Picture of a man getting an MRI scan
October 23, 2025 at 2:36 PM
prostateukprofs.bsky.social
Can expanding germline testing improve #ProstateCancer risk detection in men of African ancestry?

A great team effort led by Prof Vanessa Hayes with Prof Ros Eeles from @icr.ac.uk, and the PPCG, published in @natcomms.nature.com

Grab a ☕ and read: doi.org/10.1038/s414...
October 21, 2025 at 3:02 PM
prostateukprofs.bsky.social
📢 @cancerresearchuk.org has refreshed their career support for clinical academics, aiming to address some of the specific challenges they face.

💻 Join their webinar on 19 November to learn more and ask your questions.

Register using the link below! ⤵️

buff.ly/CZx2ANJ
CRUK Webinar titled: Refreshing our support for clinical academics. The webinar takes place on the 19th November.
October 17, 2025 at 1:10 PM