David A Hendrix
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profhendrix.bsky.social
David A Hendrix
@profhendrix.bsky.social
Professor at Oregon State University. Computational biology and nucleic acid bioinformatics.
We are excited to share a new publication w/ @JosephYesselman in @NAR_Open. RNA secondary structure prediction and design typically minimize the global free energy. We show that *local* stability compensation is a powerful way of designing RNA structures 1/4
academic.oup.com/nar/article/...
Analysis of natural structures and chemical mapping data reveals local stability compensation in RNA
Abstract. RNA molecules adopt complex structures that perform essential biological functions across all forms of life, making them promising candidates for
academic.oup.com
July 11, 2025 at 8:52 PM
We are excited to share our latest publication, bpRNA-CosMoS, a k-mer based measure of #RNA structural similarity. This method allows us to perform millions of structural comparisons for clustering in a short amount of time. #OpenAccess in #Bioinformatics
academic.oup.com/bioinformati...
bpRNA-CosMoS: a robust and efficient RNA structural comparison method using k-mer based cosine similarity
AbstractMotivation. RNA secondary structure is often essential to function. Recent work has led to the development of high-throughput experimental probing
academic.oup.com
May 6, 2025 at 6:09 PM
Reposted by David A Hendrix
Professor David Hendrix photographed this literal ray of spring equinox light shining through the skybridge connecting Cordley Hall and the Agriculture & Life Sciences Building. It’s a phenomenon he’s dubbed “BeaverHenge” because it only happens during the equinox. 🦫✨

Happy spring, everyone!
March 25, 2025 at 12:13 AM
I caught a ray of light through the sky bridge between Ag & Life Sciences and Cordley Hall tonight around 7pm. Although the equinox was two days ago, it still works. It was the first day this week that wasn't too cloudy to see anything @oregonstate.edu #beaverhenge #gobeavs!
March 23, 2025 at 3:57 AM
I'm experimenting with 3D printing #RNA with a #3Dpen! It's a work in progress. I did this a few years back, and getting back into it.
March 5, 2025 at 5:43 PM
December 26, 2024 at 8:27 PM