Pranab Chatterjee MD, PhD
@pranab.stopamr.org
Skeptic Oslerphile. PhD @johnshopkinssph.bsky.social #OneHealth #AMR #Zoonoses #InfectiousDiseases #Vaccines #Epidemiology #ClinicalTrials #IDSky + @stopamr.org: Building sustainable, healthy, AMR-resilient future. Also, @bhavnaseth.bsky.social's #1fan!
Fred Ramsdell has won the
@nobelprize.bsky.social
but may not know because he is off living his best life, hiking in Idaho. Be like Fred Ramsdell. Congratulations, Dr. Ramsdell!
@nobelprize.bsky.social
but may not know because he is off living his best life, hiking in Idaho. Be like Fred Ramsdell. Congratulations, Dr. Ramsdell!
October 7, 2025 at 5:31 AM
Fred Ramsdell has won the
@nobelprize.bsky.social
but may not know because he is off living his best life, hiking in Idaho. Be like Fred Ramsdell. Congratulations, Dr. Ramsdell!
@nobelprize.bsky.social
but may not know because he is off living his best life, hiking in Idaho. Be like Fred Ramsdell. Congratulations, Dr. Ramsdell!
I’m not sure if blogging is a thing anymore but I’ve decided to write more this year. And this is the account of how a random drive helped clear out the cobwebs in my mind. The Nocturnal Odyssey: Driving as a Pathway to Cognitive Restoration and Creative Insights: open.substack.com/pub/sceptice...
August 1, 2025 at 5:49 PM
I’m not sure if blogging is a thing anymore but I’ve decided to write more this year. And this is the account of how a random drive helped clear out the cobwebs in my mind. The Nocturnal Odyssey: Driving as a Pathway to Cognitive Restoration and Creative Insights: open.substack.com/pub/sceptice...
Meanwhile over on the other side of the spectrum, the resident AI has gone … umm … yeah. Not good.
July 9, 2025 at 3:10 PM
Meanwhile over on the other side of the spectrum, the resident AI has gone … umm … yeah. Not good.
Re-reading this classic book at a time when it’s important to re-reimagine global health. The dismantling of the US supported apparatus will be a shock, but it’s my hope that it’ll also push us to reach a more sustainable, locally-led future.
July 5, 2025 at 3:21 PM
Re-reading this classic book at a time when it’s important to re-reimagine global health. The dismantling of the US supported apparatus will be a shock, but it’s my hope that it’ll also push us to reach a more sustainable, locally-led future.
Hanging out in style! These majestic fruit bats (also known as flying foxes) are enjoying a leafy snack while chilling upside down, because why not? Native to tropical regions, these gentle pollinators play a vital role in maintaining forest ecosystems by dispersing seeds and pollinating plants.
June 23, 2025 at 4:02 AM
Hanging out in style! These majestic fruit bats (also known as flying foxes) are enjoying a leafy snack while chilling upside down, because why not? Native to tropical regions, these gentle pollinators play a vital role in maintaining forest ecosystems by dispersing seeds and pollinating plants.
Meet the Northern Bald Ibis. Punk-rock plumage and a scimitar bill to match! Once widespread across Europe, North Africa & the Middle East, it’s now listed as endangered; breeding programs in Morocco, Turkey & Europe are driving a fragile comeback. Share, donate, advocate. Extinction isn’t an option
June 22, 2025 at 3:41 AM
Meet the Northern Bald Ibis. Punk-rock plumage and a scimitar bill to match! Once widespread across Europe, North Africa & the Middle East, it’s now listed as endangered; breeding programs in Morocco, Turkey & Europe are driving a fragile comeback. Share, donate, advocate. Extinction isn’t an option
Yellow-bellied Slider (Trachemys scripta scripta) drifting under a mirrored water surface. 🌿🐢
Hear the soundtrack? Ripples tapping pads, cicadas buzzing, and a Red-eyed Vireo swapping its cheery “question-and-answer” phrases from the canopy! Wetland meditation in full surround-sound.
#nature #Turtle
Hear the soundtrack? Ripples tapping pads, cicadas buzzing, and a Red-eyed Vireo swapping its cheery “question-and-answer” phrases from the canopy! Wetland meditation in full surround-sound.
#nature #Turtle
June 22, 2025 at 3:40 AM
So @bhavnaseth.bsky.social and I thought it was a hummingbird fluttering over the milkweed, until we looked closer. Meet the Hummingbird Clearwing Moth (Hemaris thysbe), a master mimic that hovers and feeds just like its avian namesake. It is a vital native pollinator, drawn to nectar-rich plants.
June 20, 2025 at 12:16 AM
So @bhavnaseth.bsky.social and I thought it was a hummingbird fluttering over the milkweed, until we looked closer. Meet the Hummingbird Clearwing Moth (Hemaris thysbe), a master mimic that hovers and feeds just like its avian namesake. It is a vital native pollinator, drawn to nectar-rich plants.
The world’s priciest pizzas just became a billionaire’s meal. @bitcoin.bsky.social #btc #crypto Today marks 15 years since Laszlo Hanyecz purchased two pizzas for 10,000 bitcoins. Worth $1.12 billion today. #PizzaDay
May 22, 2025 at 5:46 PM
The world’s priciest pizzas just became a billionaire’s meal. @bitcoin.bsky.social #btc #crypto Today marks 15 years since Laszlo Hanyecz purchased two pizzas for 10,000 bitcoins. Worth $1.12 billion today. #PizzaDay
May 21, 2025 at 11:27 PM
May 21, 2025 at 11:26 PM
1/
In what is bound to be one of the most widely read and discussed publications, the US FDA has announced a major shift in its COVID-19 vaccination policy. Vinay Prasad and Marty Makary’s words in @nejm.org: pubmed.ncbi.nlm.nih.gov/40392534/
In what is bound to be one of the most widely read and discussed publications, the US FDA has announced a major shift in its COVID-19 vaccination policy. Vinay Prasad and Marty Makary’s words in @nejm.org: pubmed.ncbi.nlm.nih.gov/40392534/
May 21, 2025 at 3:56 PM
1/
In what is bound to be one of the most widely read and discussed publications, the US FDA has announced a major shift in its COVID-19 vaccination policy. Vinay Prasad and Marty Makary’s words in @nejm.org: pubmed.ncbi.nlm.nih.gov/40392534/
In what is bound to be one of the most widely read and discussed publications, the US FDA has announced a major shift in its COVID-19 vaccination policy. Vinay Prasad and Marty Makary’s words in @nejm.org: pubmed.ncbi.nlm.nih.gov/40392534/
Yikes. Looks like @bitcoin.bsky.social just scaled its all time high levels! #crypto
May 21, 2025 at 3:10 PM
Yikes. Looks like @bitcoin.bsky.social just scaled its all time high levels! #crypto
📊 Numbers tell part of the story. This study leans heavily quant, but even the authors say: we need deeper qualitative dives to unpack why certain terms resonate—and what people actually mean when they say they "get" AMR. #AMR #QualitativeResearch (22)
May 20, 2025 at 3:01 PM
📊 Numbers tell part of the story. This study leans heavily quant, but even the authors say: we need deeper qualitative dives to unpack why certain terms resonate—and what people actually mean when they say they "get" AMR. #AMR #QualitativeResearch (22)
Also, hat tip to the GBD Antimicrobial Resistance Collaborators for coining the even more confusing neologism – bacterial antimicrobial resistance. Great papers. Confusing titles. (18)
May 20, 2025 at 3:00 PM
Also, hat tip to the GBD Antimicrobial Resistance Collaborators for coining the even more confusing neologism – bacterial antimicrobial resistance. Great papers. Confusing titles. (18)
Not being cool enough to pull it off, I asked ChatGPT to reframe the definition of AMR. This is what it came up with:
May 20, 2025 at 2:58 PM
Not being cool enough to pull it off, I asked ChatGPT to reframe the definition of AMR. This is what it came up with:
🧠 Recall matters.
Which term stuck?
🟢 Best: "Antibiotic Resistance" – 79% recall
🔴 Worst: “Superbugs” – only 65% (once again, color me surprised!)
Despite media hype, “Superbugs” didn’t help memory. Remember the @unep.org report (www.unep.org/resources/su...)? (13)
Which term stuck?
🟢 Best: "Antibiotic Resistance" – 79% recall
🔴 Worst: “Superbugs” – only 65% (once again, color me surprised!)
Despite media hype, “Superbugs” didn’t help memory. Remember the @unep.org report (www.unep.org/resources/su...)? (13)
May 20, 2025 at 2:57 PM
🧠 Recall matters.
Which term stuck?
🟢 Best: "Antibiotic Resistance" – 79% recall
🔴 Worst: “Superbugs” – only 65% (once again, color me surprised!)
Despite media hype, “Superbugs” didn’t help memory. Remember the @unep.org report (www.unep.org/resources/su...)? (13)
Which term stuck?
🟢 Best: "Antibiotic Resistance" – 79% recall
🔴 Worst: “Superbugs” – only 65% (once again, color me surprised!)
Despite media hype, “Superbugs” didn’t help memory. Remember the @unep.org report (www.unep.org/resources/su...)? (13)
💥 Terminology impacted real behaviors (rather, declared behavioral intent).
% likely to stop antibiotics early:
🔹 AMR – 67.4%
🔹 Antibiotic Resistance – 54%
🔹 The Antibiotic Crisis – 52%
🔹 Superbugs – 68%
👉 “Antibiotic Crisis” performed best (12)
% likely to stop antibiotics early:
🔹 AMR – 67.4%
🔹 Antibiotic Resistance – 54%
🔹 The Antibiotic Crisis – 52%
🔹 Superbugs – 68%
👉 “Antibiotic Crisis” performed best (12)
May 20, 2025 at 2:56 PM
💥 Terminology impacted real behaviors (rather, declared behavioral intent).
% likely to stop antibiotics early:
🔹 AMR – 67.4%
🔹 Antibiotic Resistance – 54%
🔹 The Antibiotic Crisis – 52%
🔹 Superbugs – 68%
👉 “Antibiotic Crisis” performed best (12)
% likely to stop antibiotics early:
🔹 AMR – 67.4%
🔹 Antibiotic Resistance – 54%
🔹 The Antibiotic Crisis – 52%
🔹 Superbugs – 68%
👉 “Antibiotic Crisis” performed best (12)
🧪 Behavioral Intent:
Asked what they'd do with a sore throat (likely viral):
🟨 Few said they’d ask for antibiotics (good news).
BUT:
🚨 Those shown “Antibiotic Resistance” or “Antibiotic Crisis” were significantly less likely to say they’d stop antibiotics early. (11)
Asked what they'd do with a sore throat (likely viral):
🟨 Few said they’d ask for antibiotics (good news).
BUT:
🚨 Those shown “Antibiotic Resistance” or “Antibiotic Crisis” were significantly less likely to say they’d stop antibiotics early. (11)
May 20, 2025 at 2:56 PM
🧪 Behavioral Intent:
Asked what they'd do with a sore throat (likely viral):
🟨 Few said they’d ask for antibiotics (good news).
BUT:
🚨 Those shown “Antibiotic Resistance” or “Antibiotic Crisis” were significantly less likely to say they’d stop antibiotics early. (11)
Asked what they'd do with a sore throat (likely viral):
🟨 Few said they’d ask for antibiotics (good news).
BUT:
🚨 Those shown “Antibiotic Resistance” or “Antibiotic Crisis” were significantly less likely to say they’d stop antibiotics early. (11)
🧠 Confidence ≠ Knowledge.
Almost everyone (~98%) was confident in their comprehension—even those who were wrong.
This highlights a dangerous gap: misinformation + overconfidence.
Also, let me take this opportunity to remind everyone of my favorite graph. (10)
Almost everyone (~98%) was confident in their comprehension—even those who were wrong.
This highlights a dangerous gap: misinformation + overconfidence.
Also, let me take this opportunity to remind everyone of my favorite graph. (10)
May 20, 2025 at 2:55 PM
🧠 Confidence ≠ Knowledge.
Almost everyone (~98%) was confident in their comprehension—even those who were wrong.
This highlights a dangerous gap: misinformation + overconfidence.
Also, let me take this opportunity to remind everyone of my favorite graph. (10)
Almost everyone (~98%) was confident in their comprehension—even those who were wrong.
This highlights a dangerous gap: misinformation + overconfidence.
Also, let me take this opportunity to remind everyone of my favorite graph. (10)
💡 Secondary Outcome: Comprehension.
Participants had to answer 3 MCQs on AMR causes/solutions.
"Antibiotic Resistance" led again with a score of 66%.
"AMR" trailed at 63.3%.
Effect size small—but significant (p = 0.013). (9)
Participants had to answer 3 MCQs on AMR causes/solutions.
"Antibiotic Resistance" led again with a score of 66%.
"AMR" trailed at 63.3%.
Effect size small—but significant (p = 0.013). (9)
May 20, 2025 at 2:55 PM
💡 Secondary Outcome: Comprehension.
Participants had to answer 3 MCQs on AMR causes/solutions.
"Antibiotic Resistance" led again with a score of 66%.
"AMR" trailed at 63.3%.
Effect size small—but significant (p = 0.013). (9)
Participants had to answer 3 MCQs on AMR causes/solutions.
"Antibiotic Resistance" led again with a score of 66%.
"AMR" trailed at 63.3%.
Effect size small—but significant (p = 0.013). (9)
🧠 Primary Outcome:
Attitudes toward AMR.
✅ "Antibiotic Resistance" scored highest (86.3%)
✅ “The Antibiotic Crisis” next (85.2%)
❌ “AMR” lowest (81.0%)
The term “Superbugs” (83.2%) did worse than I would have expected.
But… the differences are quite small (though statistically significant). (8)
Attitudes toward AMR.
✅ "Antibiotic Resistance" scored highest (86.3%)
✅ “The Antibiotic Crisis” next (85.2%)
❌ “AMR” lowest (81.0%)
The term “Superbugs” (83.2%) did worse than I would have expected.
But… the differences are quite small (though statistically significant). (8)
May 20, 2025 at 2:54 PM
🧠 Primary Outcome:
Attitudes toward AMR.
✅ "Antibiotic Resistance" scored highest (86.3%)
✅ “The Antibiotic Crisis” next (85.2%)
❌ “AMR” lowest (81.0%)
The term “Superbugs” (83.2%) did worse than I would have expected.
But… the differences are quite small (though statistically significant). (8)
Attitudes toward AMR.
✅ "Antibiotic Resistance" scored highest (86.3%)
✅ “The Antibiotic Crisis” next (85.2%)
❌ “AMR” lowest (81.0%)
The term “Superbugs” (83.2%) did worse than I would have expected.
But… the differences are quite small (though statistically significant). (8)
3 co-design workshop sessions were organized to explore different ideas, 10 of which were shortlisted, and the 3 top ones chosen for this study. Participants were provided with identical informational posters to introduce them to the concept. (7)
May 20, 2025 at 2:54 PM
3 co-design workshop sessions were organized to explore different ideas, 10 of which were shortlisted, and the 3 top ones chosen for this study. Participants were provided with identical informational posters to introduce them to the concept. (7)
📊 Study design:
A 4-armed randomized online experiment with 4,296 UK adults tested 4 terms for AMR:
🔹 Antimicrobial Resistance - AMR (control)
🔹 Superbugs
🔹 Antibiotic Resistance
🔹 The Antibiotic Crisis
All received identical info except the name of the issue. (5)
A 4-armed randomized online experiment with 4,296 UK adults tested 4 terms for AMR:
🔹 Antimicrobial Resistance - AMR (control)
🔹 Superbugs
🔹 Antibiotic Resistance
🔹 The Antibiotic Crisis
All received identical info except the name of the issue. (5)
May 20, 2025 at 2:51 PM
📊 Study design:
A 4-armed randomized online experiment with 4,296 UK adults tested 4 terms for AMR:
🔹 Antimicrobial Resistance - AMR (control)
🔹 Superbugs
🔹 Antibiotic Resistance
🔹 The Antibiotic Crisis
All received identical info except the name of the issue. (5)
A 4-armed randomized online experiment with 4,296 UK adults tested 4 terms for AMR:
🔹 Antimicrobial Resistance - AMR (control)
🔹 Superbugs
🔹 Antibiotic Resistance
🔹 The Antibiotic Crisis
All received identical info except the name of the issue. (5)
This new @natcomms.nature.com study tested 4 terms for “antimicrobial resistance” (AMR)—and found that language choice affects public understanding and behavior.
Let's dive in (pretty long thread)! 🧵
🔗 doi.org/10.1038/s438... (2)
Let's dive in (pretty long thread)! 🧵
🔗 doi.org/10.1038/s438... (2)
May 20, 2025 at 2:49 PM
This new @natcomms.nature.com study tested 4 terms for “antimicrobial resistance” (AMR)—and found that language choice affects public understanding and behavior.
Let's dive in (pretty long thread)! 🧵
🔗 doi.org/10.1038/s438... (2)
Let's dive in (pretty long thread)! 🧵
🔗 doi.org/10.1038/s438... (2)