Physics of Life Leuven
banner
pol-kuleuven.bsky.social
Physics of Life Leuven
@pol-kuleuven.bsky.social
The KU Leuven Physics of Life cluster (PoL@KUL) organizes research initiatives aimed at studying the behavior of biological systems from a Physics perspective.

https://fys.kuleuven.be/zmb/PoLatKUL
https://www.kuleuven.be/english

#softmatter #biophysics
Working on biosensors? Don’t miss this MDPI webinar introducing thermal biosensing via the heat-transfer method (HTM) — a simple yet powerful way to detect biomolecular interactions and monitor cells.
Pioneers of HTM will share their insights!
#Biosensors #HTM
More info: sciforum.net/event/Sensor...
October 8, 2025 at 12:16 PM
🌱 Our young researchers made us so proud at #Biosensors2025 in Lisbon! Representing KU Leuven and #PhysicsOfLife with scientific excellence and innovation on the international stage. #KULeuven #researchimpact #biosensors
June 8, 2025 at 6:08 AM
🧬 Next week we’re thrilled to host Prof. Nick Gilbert (U. of Edinburgh) for a deep dive into the Structure & Dynamics of active chromatin!
🎙️ “Irregular nucleosome positioning modulates 3D structure and dynamics of active chromatin”

#Chromatin #Biophysics #GeneRegulation
June 8, 2025 at 5:37 AM
New paper out from Patrick Wagner Group! We tested a prototype HTM (heat transfer method) device to assess antimicrobial efficacy.

#Biophysics #HTM #Biosensors #Antimicrobials #COMSOL #DrugScreening

More information here: www.mdpi.com/1424-8220/25...
May 7, 2025 at 11:55 AM
🚨 New paper out from Patrick Wagner Group! We developed a low-cost, portable electrochemical sensor for detecting PFOA — one of the most persistent PFAS pollutants — on-site and down to very low levels.

#PFAS #Sensors #WaterQuality #MIPs #EnviroTech

pubs.acs.org/doi/full/10....
Tracking Perfluorooctanoic Acid in Tap and River Water Employing Screen-Printed Electrodes Modified with Molecularly Imprinted Polymers
While existing polyfluoroalkyl substances (PFAS) detection techniques are highly sensitive, their broader implementation is limited by the need for expensive equipment, lengthy analysis times, and specialized personnel. This underscores the need for fast, reliable, cost-effective, and accessible PFAS detection methods to avoid exposure to these pollutants and expedite the remediation of contaminated environments. Currently, portable electrochemical sensors for in situ contaminant detection are gaining significant attention. This study focuses on developing an electrochemical sensor for on-site perfluorooctanoic acid (PFOA) detection utilizing screen-printed electrodes (SPEs) modified with molecularly imprinted polymers (MIPs). The sensor’s performance is evaluated using electrochemical impedance spectroscopy (EIS), with the electrochemical signals for PFOA detection arising from the specific interactions between MIPs and PFOA. The sensor exhibits a linear response to PFOA in phosphate-buffered saline within a concentration range of 0.1 nM to 10 μM, a detection limit of 19 ± 1 pM, and a quantification limit of 42 ± 3 nM. The selectivity of the sensor is assessed by measuring its response to four different PFAS compounds. Additionally, its real-world applicability is tested by analyzing the EIS response in tap and river water samples. The developed sensor, which combines an easy-to-use dipstick format with readily prepared SPEs, has the potential for large-scale production for in situ PFOA detection.
pubs.acs.org
April 25, 2025 at 10:49 AM
Happy to share our new paper - "Hydrogen peroxide sensing with cochlear implants in vivo: Towards intra-operative trauma detection" - is now published!

Check it out here: www.sciencedirect.com/science/arti...

#CochlearImplants #ElectrochemicalSensing #InflammationMonitoring
Hydrogen peroxide sensing with cochlear implants in vivo: Towards intra-operative trauma detection
Despite advancements in soft surgical techniques and electrodes, intra-cochlear trauma during cochlear implant (CI) insertion still occurs and can har…
www.sciencedirect.com
April 23, 2025 at 12:04 PM
Exciting news! PoL@KUL invites you to the inaugural lecture of the International Francqui Professor 2024-25, Prof. Davide Marenduzzo (U. of Edinburgh) on Tuesday, April 29, 2025 in Leuven:

Biophysical principles of chromosome organisation

Info and registration:

fys.kuleuven.be/english/coll...
April 3, 2025 at 1:50 PM
PoL Jobs! Prof. Thomas Cocolios is offering 2 fully-funded PhD positions to work between KU Leuven and JRC Karlsruhe on improving the supply of alpha-emitting medical radionuclides for research:
www.kuleuven.be/personeel/jo...
2 Joint PhD positions with JRC Karlsruhe for medical radionuclide production
Research at a top European nuclear facility for tomorrow's cancer treatments
www.kuleuven.be
April 3, 2025 at 10:07 AM
Tomorrow 05/03/2025, Prof. Takahiro Sakaue from Aoyama-Gakuin University, Tokyo will share with us his recent findings on chromatin dynamics in C. Elegans Embryos !
March 4, 2025 at 3:14 PM
Reposted by Physics of Life Leuven
Just published in J Chem Phys @aip.bsky.social special issue on "Chromatin Structure and Dynamics". I will tell more on this work in a future post. Collaboration with @lremini.bsky.social, M. Segers and A. Parmeggiani.
doi.org/10.1063/5.02...
Inferring interphase chromosomal structure from multiplexed fluorescence in situ hybridization data: A unified picture from human and mouse cells
We analyze multiplexed fluorescence in situ hybridization (m-FISH) data for human and mouse cell lines. The m-FISH technique uses fluorescently-labeled single-s
doi.org
February 5, 2025 at 1:17 PM
Yesterday, we had the pleasure of hosting a group of students from Sint-Pieterscollege sintpieterscollege.be! After a presentation on biosensors, they got a hands-on look at liquid crystals.
February 19, 2025 at 3:56 PM
First post since our migration to Bluesky! Yesterday we had the pleasure to receive Prof. Steffi Krause from Queen Mary University of London.
www.sems.qmul.ac.uk/research/gro...
Prof. Krause gave an exciting talk on Photoelectrical imaging for live cell monitoring and sensor applications.
January 22, 2025 at 12:58 PM