Pierre-Marie Bertrand
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pmbertrand.fr
Pierre-Marie Bertrand
@pmbertrand.fr
Interested in #BioEthic and #ResearchEthic.
(1) Intensive Care Practitioner @ Cannes General Hospital, France.
(2) PhD student @ Aix Marseille Univ, CNRS, EFS, ADES, Marseille, France
https://orcid.org/0000-0002-2285-5638
🎓 Ouverture du colloque national des Espaces de Réflexion Éthique Régionaux (#ERER) à Reims !
Deux jours pour penser ensemble l’accès aux soins des personnes en situation de handicap :
justice, autonomie, solidarité et dignité au cœur du débat.
👉 Programme : erege.fr#Ethiqueu#Handicapa#Santéé
https://erege.fr
November 12, 2025 at 12:32 PM
Substituted judgment in surrogate decision-making rests on a shaky moral assumption: authenticity. Since patients differ in how “authentic” their lives are, “what the patient would want” can’t always be decisive.
🔗 doi.org/10.1080/1526...
#ResearchEthics
doi.org
October 29, 2025 at 5:30 AM
Reposted by Pierre-Marie Bertrand
Verdict cette année au lendemain des vaccins: mon épaule gauche (ARNm COVID) est deux fois plus gonflée que la droite (grippe) quasi indolore. Si vous hésitez gaucher/droitier vous le saurez.

La campagne de vaccination c'est maintenant, pas en janvier. #Rappel
October 25, 2025 at 4:17 PM
Reposted by Pierre-Marie Bertrand
🫀 Journée mondiale du don d’organes.
Merci à nos partenaires engagés : @MProvence, @Chiesi, @Département13, @FranceADOT, @univ-amu.fr, @SFT.
Parlons-en. Ensemble, on informe, on transmet, on sauve.
💬 Et vous, en avez-vous parlé à vos proches ?
#DonDOrganes
October 17, 2025 at 8:53 AM
📊 @jama.com study by @emilymoin.com shows how U.S. ICU care changed 2014–2023:
- Mortality ↑ during COVID, then returned to baseline
- Mechanical ventilation ↓ below prepandemic levels
- Vasopressor use tripled, remains high
ICU practices are shifting.
doi:10.1001/jama.2025.2163 #CriticalCare
September 21, 2025 at 8:46 AM
🧠 In @nejm.org, Raja-Elie Abdulnour et al. warn: AI in medical training risks deskilling & mis-skilling. They propose DEFT-AI to teach critical thinking & safe human-AI collaboration. Verify, then trust.
📖 doi.org/10.1056/NEJM...
#ResearchEthics #MedicalEducation
Educational Strategies for Clinical Supervision of Artificial Intelligence Use | NEJM
Many learners are more facile with the use of large language models in medicine than their supervisors are. The authors provide an approach to clinical supervision that can mitigate the perils and ...
doi.org
August 24, 2025 at 6:00 PM
Reposted by Pierre-Marie Bertrand
🚨 New Publication Alert

“Chat-IRB? How Application‑Specific Language Models Can Enhance Research Ethics Review” — now available online ahead of print in the Journal of Medical Ethics (5 August 2025). jme.bmj.com/content/earl...
August 7, 2025 at 2:28 AM
🧠 Can AI support ethics committees without replacing them?
Porsdam Mann & @briandavidearp.bsky.social propose IRB-specific LLMs to streamline reviews, reduce delays, and assist—not replace—human judgment. A major step to ease the daily burden.
📖 doi.org/10.1136/jme-...
#ResearchEthics #AI #Bioethics
Chat-IRB? How application-specific language models can enhance research ethics review
Institutional review boards (IRBs) play a crucial role in ensuring the ethical conduct of human subjects research, but face challenges including inconsistency, delays, and inefficiencies. We propose t...
doi.org
August 6, 2025 at 4:42 AM
Reposted by Pierre-Marie Bertrand
new RCT just came out on the management of acute necrotic collections (ANC) that may complicate necrotizing pancreatitis

ANCs are early sterile collections containing fluid and sometimes debris

they *lack* a well-defined wall (unlike pseudocysts or walled-off necrosis)...

🧵 #1/ #EMIMCC
August 2, 2025 at 1:27 PM
🧪 In AJOB, Jake Earl et al. warn of a new ethical risk in clinical trials: the Social Value Misconception. Altruistic participants may falsely believe in exaggerated benefits for society—compromising consent and autonomy.
📖 doi.org/10.1080/1526...
#Bioethics #ResearchEthics
The Social Value Misconception in Clinical Research
Clinical researchers should help respect the autonomy and promote the well-being of prospective study participants by helping them make voluntary, informed decisions about enrollment. However, part...
doi.org
August 1, 2025 at 4:50 PM
😷 In @atscommunity.bsky.social , Lautrette et al. find that ICU visitation restrictions during COVID-19 didn’t increased anxiety, depression, or PTSD in relatives. Key risk factors : Female, spouse, poor communication.
📖 www.atsjournals.org/doi/10.1164/...
#ICU #MentalHealth #COVID19
Impact of Visitation Restrictions in ICU on Psychological Symptoms in Family Members: Experience of the COVID-19 Pandemic | American Journal of Respiratory and Critical Care Medicine | Articles in Pre...
www.atsjournals.org
July 28, 2025 at 1:58 AM
🧠 In @accpchest.bsky.social, Dr Tietbohl & Moss explore strategies to improve surrogate informed consent in ICU research: Dedicates Research Coordinator (over PI), timing, trust, and clarity matter most.
Time to standardize and fix consent!
📖 journal.chestnet.org/article/S001...
#ResearchEthics
Approaches for establishing trust and alleviating stress during the surrogate informed consent process for critical care research
We identified three strategies that PIs, RCs, SDMs and patients viewed as effective for building trust and alleviating stress in the surrogate informed consent process. Incorporating these approaches ...
journal.chestnet.org
July 23, 2025 at 4:53 AM
Reposted by Pierre-Marie Bertrand
Now published 🚨 When to create embryos or organoids for research | Journal of Medical Ethics jme.bmj.com/content/earl...
July 20, 2025 at 12:48 PM
Reposted by Pierre-Marie Bertrand
On a besoin d’un petit coup de main 💬
On recrute des infirmier·ères en psychiatrie pour nos équipes à l’Hôpital de la Conception, à Marseille.
Un partage, un relais, un mot : ça peut vraiment aider.
Merci à celles et ceux qui feront passer le message 💙
Jérémi, infirmier en psychiatrie à la Conception - Un métier authentique, une équipe solide
YouTube video by AP-HM - Hôpitaux Universitaires de Marseille
youtu.be
July 18, 2025 at 1:02 PM
🧠 In J Med Ethics, Sebastian Porsdam Mann & @briandavidearp.bsky.social argue that how we define moral status—by potential or current capacities—should guide the ethics of brain organoids and human embryonic neural tissue research.
📖 jme.bmj.com/content/earl...
#ResearchEthics #Bioethics
When to create embryos or organoids for research
The development of brain organoids and use of human embryonic neural structures for research each raise distinct ethical considerations that require careful analysis. We propose that rather than attem...
jme.bmj.com
July 18, 2025 at 6:48 AM
🫀 Landmark innovation in #HeartTransplant: in today’s @nejm.org Williams et al. present REUP, a low-cost, ethically sound method to recover hearts after circulatory death—no ex situ device, no reanimation. Early results looks promising.
📖 doi.org/10.1056/NEJM...
#Graft #Transplantation
Rapid Recovery of Donor Hearts for Transplantation after Circulatory Death | NEJM
We report a method for the recovery of hearts for transplantation from deceased donors after circulatory death that obviates the need for thoracoabdominal normothermic regional perfusion or ex situ...
doi.org
July 17, 2025 at 8:28 PM
🦠 In ICU pneumonia, rapid PCR like FilmArray® helps diagnose—but can it predict outcomes?
Julien Dessajan et al. show that FA-PP tracks bacterial decline but fails to foresee clinical success.
Initial test: yes ✅
Repeat testing: not so fast 🚫
🔗 doi.org/10.1186/s130...
#IntensiveCare #VAP
Assessing FilmArray Pneumonia+ panel dynamics during antibiotic treatment to predict clinical success in ICU patients with ventilated hospital-acquired pneumonia and ventilator-associated pneumonia: a...
Background Accurate microbiological documentation seems central for managing severe pneumonia. While the FilmArray® Pneumonia + panel (FA-PP) offers rapid pathogen identification, its effectiveness du...
doi.org
July 14, 2025 at 9:20 PM
🧪 In a national survey, @haaserthibaud.bsky.social et al. show 84% of oncologists face therapeutic misconception—yet many miss or even reinforce it. Ethics training changes that.
🙌 It’s time to act to strengthen consent and research integrity.
📖 doi.org/10.1186/s129...
#ResearchEthics
Oncologists’ knowledge, practices and ethical opinions about therapeutic misconception: a French national survey - BMC Medical Ethics
Background Therapeutic misconception (TM) among research participants refers to the conflation of research goals (generating generalisable knowledge) with clinical care goals (making the best decision...
doi.org
July 13, 2025 at 6:52 AM
@drn4z.bsky.social: Maybe it’s worth a shot? Let’s bring it up with Philips next time we meet about ICCA!
July 12, 2025 at 10:30 AM
👨‍💻We are still stuck with digital versions of paper charts!
Chute in @intenscaremed.bsky.social calls for normalized EHR data to unlock clinical insight such AI and interoperability.
We must rethink our EHRs—the future demands structured data.
🔗 pmc.ncbi.nlm.nih.gov/articles/PMC... #ResearchEthics
A common longitudinal intensive care unit data format (CLIF) for critical illness research
Critical illness threatens millions of lives annually. Electronic health record (EHR) data are a source of granular information that could generate crucial insights into the nature and optimal treatme...
pmc.ncbi.nlm.nih.gov
July 12, 2025 at 8:56 AM
📺 "Au nom de la science, la recherche sur l'homme" : l'encadrement de la recherche médicale, du procès de Nuremberg aux lois actuelles. Scandales et prises de conscience font naître une éthique de la recherche.
👉 10/07 20h30 LCP : www.lemonde.fr/sciences/art...
#Consentement #ResearchEthics
Programme TV : « Au nom de la science, la recherche sur l’homme » sur LCP, le long chemin vers l’encadrement légal
Anja Unger, retrace, depuis le procès de Nuremberg, la prise en compte progressive de l’éthique en matière d’expérimentations médicales sur l’humain, en France et aux Etats-Unis.
www.lemonde.fr
July 11, 2025 at 5:00 AM
🧠 Can you truly give informed consent if you can’t grasp the outcome?
Daniel Villiger tackles the “ignorance challenge” and defends informed consent—even under deep uncertainty.
Autonomy & vulnerability…

🔗 doi.org/10.1080/1526...
#Bioethics #MedicalEthics #ResearchEthics
Informed Consent Under Ignorance
In recent years, an old challenge to informed consent has been rediscovered: the challenge of ignorance. Several authors argue that due to the presence of irreducible ignorance in certain treatment...
doi.org
July 8, 2025 at 5:09 AM
🗣 Niek Kok et al. explore how clinicians and families reconstruct treatment preferences for patients with disorders of consciousness. Three epistemic models—correspondence, coherence, and communitarian—frame this ethically charged practice.

🔗 doi.org/10.1186/s129...
#ResearchEthics #Bioethics
Reconstruction of patients' treatment preferences in disorders of consciousness: a systematic review - BMC Medical Ethics
Background Patients with disorders of consciousness (DoC) are unable to partake in the decision making process concerning their treatment. In the process of medical decision-making, which in DoC often...
doi.org
July 6, 2025 at 5:15 AM