Excited to publish on more treatment options for MGTS, a severe thrombotic disease. This study discusses the use of pirtobrutinib, a third-generation BTK inhibitor in the second case of "HIT-like" MGTS reported (1st case: Blood. 2023 Apr 6;141(14):1772-1776).

onlinelibrary.wiley.com/doi/10.1002/...

Mayo Clinic will be organizing this year‘s classical hematology conference in Arizona! If you work in this area or are curious to learn more about topics in this exciting field, join us! The link below provide more information and sign up instructions:

news.mayocliniclabs.com/mayo-clinic-...

Are anti- platelet factor 4 antibodies a cause of recurrent miscarriage?
This data suggests they may be

www.nejm.org/doi/full/10....

Along with collaborators at UT Southwestern Medical Center we report a study in the New England Journal of Medicine on the potential role of monoclonal anti-Platelet Factor 4 (PF4) antibodies in recurrent pregnancy loss. Larger studies to follow!

www.nejm.org/doi/full/10....

Great article in CAP TODAY on the expanding group of anti-PF4 disorders!! MGTS (monoclonal gammopathy of thrombotic significance) with its “flavors”, “HIT-like”, “VITT-like” & “non-HIT/VITT-like”, is going to be an important entity in the thrombophilia field!!
www.captodayonline.com/spectrum-of-...

Thanks to the Hematologist for spotlighting our work!!

The blood of a man who deliberately injected himself with snake venom for nearly 2 decades has led to an "unparalleled" antivenom, say scientists.

Antibodies found in his blood can protect against fatal doses from a wide range of species in animal tests.

🧪🩸🐍🐍🐍🐍
www.bbc.com/news/article...

Excited to see technology developed by Dr. David Murray and I in the "Technology Spotlight" section of the "Hematologist". It helps detect a novel thrombophilia, MGTS. It is gratifying to see that this is providing answers to patients with this severe disorder.

ashpublications.org/thehematolog...

Thanks to the ASH for discussing a new flavor of anti-PF4 antibodies! This antibody we published on recently in the NEJM is neither HIT-like or VITT-like. Many thanks to @rapidnovor.bsky.social for their expertise! Here is the feature in the Hematologist:

ashpublications.org/thehematolog...

The new thrombophilia, MGTS gets more interesting, and complicated! Here is a new paper in NEJM from our group on the challenges of recognizing this disorder: www.nejm.org/doi/10.1056/...
Couple of other recent papers on MGTS: www.nejm.org/doi/full/10....
ashpublications.org/blood/articl...