Pawel Lorkiewicz
pklork01.bsky.social
Pawel Lorkiewicz
@pklork01.bsky.social
Mass Spec nerd and Associate Professor at University of Louisville
I create extensive exposomics and stable isotope resolved metabolomics workflows to link environmental exposures with health outcomes. Current focus: Phase II metabolomics
Starting my #ASMS2025 adventure with Waters users meeting. The TQ Absolute XR is definitely a highlight (we have the Absolute and we like it a lot; an increase in robustness is definitely a welcome feature).
Decent talks. Getting almost too technical at times but I've learned a lot.
#TeamMassSpec
June 1, 2025 at 7:31 PM
#ASMS2025 is just around the corner. This year we will have two presentations (poster and oral) discussing our approach to #LC-MS profiling and analysis of Phase II metabolites in the urine. #teammassspec
May 23, 2025 at 4:25 PM
Our latest manuscript describes an #LCMS platform profiling Phase II metabolites. We annotated 424 mercapturates, glucuronides, sulfates linked to over 200 environmental chemicals. This demonstrates ILGA's value for advancing #Exposomics
Link doi.org/10.1016/j.en...

#MassSpectrometry #Metabolomics
May 8, 2025 at 6:55 PM
Our paper describing a dilute-and-shoot targeted LC-MS/MS method for measuring 35 urinary metabolites of #VOCs
and #tobacco alkaloids is now published in Journal of Chromatography B. The article is available here: www.sciencedirect.com/science/arti...
#MassSpecRSS #teamMassSpec #LC-MS #exposomics
January 20, 2025 at 7:48 PM
Here's a preprint of our manuscript papers.ssrn.com/sol3/papers.... a result of ~2 yr of work on #LC-MS ILGA workflow for comprehensive Phase II #metabolomics analysis. We highlight ILGA's use in #exposomics and elucidate impact of #environmental exposures on health.
#MassSpecRSS #MassSpectrometry
January 3, 2025 at 6:51 PM
This manuscript just came out in JBC
I'm glad we got to collaborate with Dr Wysoczynski and Tyler Jobe from his lab. Together with De Silva we provided stable isotope resolved #metabolomics data used in the manuscript.
Link: www.sciencedirect.com/science/arti...
#teammasspec #envirome
December 17, 2024 at 4:02 PM
Our paper describing a dilute-and-shoot targeted LC-MS/MS method for measuring 35 urinary metabolites of #VOCs and #tobacco alkaloids is currently under review. The article is available as a pre-print here:
papers.ssrn.com/sol3/papers....

#exposomics #LCMS #massspec #tobaccoresearch
December 10, 2024 at 8:40 PM