Paul J Planet
pjplanet.bsky.social
Paul J Planet
@pjplanet.bsky.social
Pediatric Infectious Disease Doctor, Evolutionary Microbiologist
Here is our latest on finding recombination in microbial genomes. No alignment, no phylogeny. Just information theory. Congrats Apurva and the whole team! This one was a pongvtime coming. academic.oup.com/mbe/article/...
What Do We Gain When Tolerating Loss? The Information Bottleneck Wrings Out Recombination
Abstract. Most microbes have the capacity to acquire genetic material from their environment. Recombination of foreign DNA yields genomes that are, at leas
academic.oup.com
March 10, 2025 at 9:00 PM
Reposted by Paul J Planet
This study was made possible through an amazing collaboration across the CHOP NICU, CHOP Infectious Disease Diagnostics Lab (IDDL), CHOP Infection Prevention and Control, the Microbial Archive and Cryocollection at CHOP (MicrobialARC), and @centermicrobialmed.bsky.social.
March 1, 2025 at 1:21 PM
Reposted by Paul J Planet
In this study we tracked carriage, transmission, and invasive infection with S. aureus across 33 months in the NICU. Using longitudinal WGS, we identify risk factors for transmission of invasive clones, and show strains that are transmitted more rapidly are more likely to cause invasive disease
March 1, 2025 at 1:21 PM
Reposted by Paul J Planet
Excited to share our work with @pjplanet.bsky.social and @ahmedmicrobes.bsky.social tracking Staph aureus transmission across the NICU using genomics!!

This study was co-led by the amazing @qianxuan.bsky.social and Lakshmi Srinivasan, and made possible by the @centermicrobialmed.bsky.social
Transmission of Staphylococcus aureus in the neonatal intensive care unit predicts invasive infection
Background Staphylococcus aureus is a leading cause of healthcare-associated infection and is one of the most common pathogens causing serious invasive infection in the neonatal intensive care unit (N...
www.medrxiv.org
March 1, 2025 at 1:21 PM
Our preprint on genomic epidemiology in the NICU! Strains that transmit faster also cause more invasive disease! nam10.safelinks.protection.outlook.com?url=https%3A...
Transmission of Staphylococcus aureus in the neonatal intensive care unit predicts invasive infection
Background : Staphylococcus aureus is a leading cause of healthcare-associated infection and is one of the most common pathogens causing serious invasive infection in the neonatal intensive care unit ...
nam10.safelinks.protection.outlook.com
February 28, 2025 at 2:00 PM