Maik Pietzner
@pietznerm.bsky.social
Professor for Health Data Modelling @Charité and @PHURI | Making better medicines | Daddy of three | Views are my own
Reposted by Maik Pietzner
It was researchers, predominantly working in public sector universities & laboratories, who developed many of the ideas & techniques that are now being used on a massive scale by the big tech companies.
Maria Leptin's (@marialep.bsky.social) speech @europarl.europa.eu erc.europa.eu/news-events/...
Maria Leptin's (@marialep.bsky.social) speech @europarl.europa.eu erc.europa.eu/news-events/...
ERC President’s speech to the European Parliament's ITRE Committee
ERC President Professor Maria Leptin' gave a speech as part of an exchange of views with the European Parliament's ITRE Committee, Brussels.
erc.europa.eu
March 4, 2025 at 12:09 PM
It was researchers, predominantly working in public sector universities & laboratories, who developed many of the ideas & techniques that are now being used on a massive scale by the big tech companies.
Maria Leptin's (@marialep.bsky.social) speech @europarl.europa.eu erc.europa.eu/news-events/...
Maria Leptin's (@marialep.bsky.social) speech @europarl.europa.eu erc.europa.eu/news-events/...
Reposted by Maik Pietzner
I see lots of patients with obesity who develop heart attacks. Often they have normal cholesterol, blood pressure and glucose levels are normal.
So why do they get heart attacks?
We identified endotrophin as a mechanism whereby obesity causes heart disease. 🧵
www.nature.com/articles/s41...
So why do they get heart attacks?
We identified endotrophin as a mechanism whereby obesity causes heart disease. 🧵
www.nature.com/articles/s41...
Integrative proteogenomic analysis identifies COL6A3-derived endotrophin as a mediator of the effect of obesity on coronary artery disease - Nature Genetics
Two-step Mendelian randomization, combined with multiple layers of omics evidence, implicates COL6A3-derived endotrophin as a mediator of coronary artery disease risk in the context of obesity.
www.nature.com
January 26, 2025 at 9:08 PM
I see lots of patients with obesity who develop heart attacks. Often they have normal cholesterol, blood pressure and glucose levels are normal.
So why do they get heart attacks?
We identified endotrophin as a mechanism whereby obesity causes heart disease. 🧵
www.nature.com/articles/s41...
So why do they get heart attacks?
We identified endotrophin as a mechanism whereby obesity causes heart disease. 🧵
www.nature.com/articles/s41...
Reposted by Maik Pietzner
Here's our latest work on proteome profiling of self-sampled dried blood spots to gain insights into the heterogeneity of the immune response against infections and vaccinations. We enrolled random citizens by postal mail to learn more about the molecular effects beyond those seeking medical care.
Multi-molecular phenotyping in a self-sampling population https://www.medrxiv.org/content/10.1101/2025.01.14.25320405v1
January 15, 2025 at 6:40 PM
Here's our latest work on proteome profiling of self-sampled dried blood spots to gain insights into the heterogeneity of the immune response against infections and vaccinations. We enrolled random citizens by postal mail to learn more about the molecular effects beyond those seeking medical care.
⭐Preprint alert⭐
Blood #Proteomics can now measure 1000s of proteins, but what can they tell us?
We used #MachineLearning in @ukbiobank.bsky.social to derive the foundations of plasma levels >3k proteins among 40 people.
www.medrxiv.org/content/10.1...
Blood #Proteomics can now measure 1000s of proteins, but what can they tell us?
We used #MachineLearning in @ukbiobank.bsky.social to derive the foundations of plasma levels >3k proteins among 40 people.
www.medrxiv.org/content/10.1...
Machine learning-guided deconvolution of plasma protein levels
Proteomic techniques now measure thousands of circulating proteins at population scale, driving a surge in biomarker studies and biological clocks. However, their potential impact, generalisability, a...
www.medrxiv.org
January 13, 2025 at 8:27 AM
⭐Preprint alert⭐
Blood #Proteomics can now measure 1000s of proteins, but what can they tell us?
We used #MachineLearning in @ukbiobank.bsky.social to derive the foundations of plasma levels >3k proteins among 40 people.
www.medrxiv.org/content/10.1...
Blood #Proteomics can now measure 1000s of proteins, but what can they tell us?
We used #MachineLearning in @ukbiobank.bsky.social to derive the foundations of plasma levels >3k proteins among 40 people.
www.medrxiv.org/content/10.1...