phoebedownes.bsky.social
@phoebedownes.bsky.social
Reposted
New Research

Global burden of lower respiratory infections and aetiologies, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023

www.thelancet.com/journals/lan...
Global burden of lower respiratory infections and aetiologies, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023
This comprehensive analysis underscores both the gains achieved through vaccination and the challenges that remain in controlling the LRI burden globally. Furthermore, it demonstrates persistent dispa...
www.thelancet.com
December 16, 2025 at 9:10 AM
Reposted
New comment:

The genomic surveillance gap: averting the antimicrobial resistance pandemic requires global equity and action

www.thelancet.com/journals/lan...
The genomic surveillance gap: averting the antimicrobial resistance pandemic requires global equity and action
The COVID-19 pandemic provided a stark, real-time demonstration of genomic surveillance's power. By sequencing SARS-CoV-2, the global health community tracked viral evolution, identified variants of c...
www.thelancet.com
November 24, 2025 at 8:37 AM
Reposted
New Review

British Society for Medical Mycology best practice recommendations for the diagnosis of serious fungal diseases: 2025 update

www.thelancet.com/journals/lan...
British Society for Medical Mycology best practice recommendations for the diagnosis of serious fungal diseases: 2025 update
The fungal diagnostic landscape is evolving; whereas previously, traditional culture-based methods dominated, most invasive fungal disease is now diagnosed with non-culture-based tests, including dire...
www.thelancet.com
November 11, 2025 at 8:12 AM
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New Personal View

Post-tuberculosis lung disease: a case definition for use in research studies

www.thelancet.com/journals/lan...
Post-tuberculosis lung disease: a case definition for use in research studies
Despite growing awareness of the substantial burden of long-term pulmonary impairment among tuberculosis survivors, marked variability in how post-tuberculosis lung disease is defined across research ...
www.thelancet.com
November 11, 2025 at 8:13 AM
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New Comment

Negative results in long COVID clinical trials: choosing outcome measures for a heterogeneous disease

www.thelancet.com/journals/lan...
Negative results in long COVID clinical trials: choosing outcome measures for a heterogeneous disease
Long COVID is an umbrella term for the heterogeneous long-term consequences of SARS-CoV-2 infection. It encompasses a wide spectrum of phenotypes (sometimes overlapping), and its underlying mechanisms...
www.thelancet.com
November 9, 2025 at 7:52 PM
Reposted
📅 @phoebedownes.bsky.social will be attending ID Week, #IDWeek (19-22 October) in Atlanta, GA on behalf of The Lancet Infectious Diseases!

📧Feel free to reach out with enquiries. Explore our scope, reach & impact, commitment to publishing excellence, & more: hubs.li/Q03BL6Th0
October 13, 2025 at 11:26 AM
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Richard Horton's latest Offline: The unavoidable reckoning tinyurl.com/3b7h5729
Offline: The unavoidable reckoning
When we held our Lancet–UNRWA–WHO–IFMSA side-event at the World Health Assembly in May this year, I doubt that anyone in the room thought the health crisis in Gaza could get much worse. Rik Peeperkorn...
tinyurl.com
September 12, 2025 at 3:27 PM
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New comment:

What can be learnt from the world's first national vaccination programme against gonorrhoea

www.thelancet.com/journals/lan...
What can be learnt from the world's first national vaccination programme against gonorrhoea
Gonorrhoea, the disease caused by Neisseria gonorrhoeae, is a bacterial sexually transmitted infection (STI) that remains a major public health concern globally, with rising incidence and increasing a...
www.thelancet.com
August 21, 2025 at 10:46 AM
Reposted
New Series- Prevention and Management of Infections in People who are Immunocompromised. Two papers on the prevention and management of infections in people who are immunocompromised, a group often neglected in research efforts and so frequently missing from the pages of our journal.
August 12, 2025 at 10:28 AM
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New Research:

Safety and immunogenicity of novel live attenuated type 1 and type 3 oral poliomyelitis vaccines in healthy adults in the USA: a first-in-human, observer-masked, multicentre, phase 1 randomised controlled trial

www.thelancet.com/journals/lan...
Safety and immunogenicity of novel live attenuated type 1 and type 3 oral poliomyelitis vaccines in healthy adults in the USA: a first-in-human, observer-masked, multicentre, phase 1 randomised contro...
nOPV1 and nOPV3 were well tolerated and showed similar immunogenicity and shedding profiles to mOPV1 and mOPV3, respectively, supporting progression of these vaccine candidates to phase 2 studies.
www.thelancet.com
August 14, 2025 at 7:33 AM
Reposted
New reserach

Molnupiravir or nirmatrelvir–ritonavir plus usual care versus usual care alone in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

www.thelancet.com/journals/lan...
Molnupiravir or nirmatrelvir–ritonavir plus usual care versus usual care alone in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial
Adding molnupiravir or nirmatrelvir–ritonavir to usual care was not associated with improvements in clinical outcomes. However, low recruitment meant a clinically meaningful benefit of treatment could...
www.thelancet.com
May 16, 2025 at 10:01 AM
Reposted
Important reporting from my NPR colleagues on the human impacts of the cuts to U.S. foreign assistance. They share the story of twelve people - including kids - who have run out of HIV drugs in Zambia.
Haunted by hopelessness: 12 Zambians share their stories as HIV drugs run out
Mothers and children, husbands and wives, doctors, truck drivers and religious leaders are all grappling with the fallout from the sudden U.S. cuts in aid.
www.npr.org
April 14, 2025 at 6:33 PM
Reposted
New research:

Nirmatrelvir–ritonavir versus placebo–ritonavir in individuals with long COVID in the USA (PAX LC): a double-blind, randomised, placebo-controlled, phase 2, decentralised trial

www.thelancet.com/journals/lan...
Nirmatrelvir–ritonavir versus placebo–ritonavir in individuals with long COVID in the USA (PAX LC): a double-blind, randomised, placebo-controlled, phase 2, decentralised trial
Nirmatrelvir–ritonavir administered for 15 days did not significantly improve health outcomes in participants with long COVID compared with placebo–ritonavir at day 28. However, the study showed the f...
www.thelancet.com
April 4, 2025 at 7:59 AM
Reposted
New research:

Rates of infection with other pathogens after a positive COVID-19 test versus a negative test in US veterans (November, 2021, to December, 2023): a retrospective cohort study

www.thelancet.com/journals/lan...
Rates of infection with other pathogens after a positive COVID-19 test versus a negative test in US veterans (November, 2021, to December, 2023): a retrospective cohort study
Our results suggest that a positive test for COVID-19 (vs a negative test) was associated with increased rates of diagnosis of various infections in the 12 months following an acute SARS-CoV-2 infecti...
www.thelancet.com
April 2, 2025 at 12:43 PM
Reposted
New editorial:

Facts and myths about measles

www.thelancet.com/journals/lan...
March 7, 2025 at 10:12 AM
Reposted
New series on Zika virus, together with @lancetmicrobe.bsky.social

4 papers on priorities for prepardeness and response

www.thelancet.com/series/zika-...
Zika Virus: Research Priorities for Preparedness and Response
www.thelancet.com
February 28, 2025 at 3:53 PM