Philipp Lange (he/him)
@philipplange.bsky.social
Translational #Proteomics & #Bioinformatics #ChildhoodCancer @UBC
Mechanistic role and #PrecisionMedicine of #PTM & #oncoproteoforms. #SingleCellProteomics, #ML & #LLM
Retweet ≠ endorsement
langelab.med.ubc.ca
Mechanistic role and #PrecisionMedicine of #PTM & #oncoproteoforms. #SingleCellProteomics, #ML & #LLM
Retweet ≠ endorsement
langelab.med.ubc.ca
Reposted by Philipp Lange (he/him)
The JPR issue on Single-Cell Omics is out.
As the editorial highlights, understanding biological systems requires direct measurements at all molecular levels.
Unlocking the Potential of Single-Cell Omics
pubs.acs.org/doi/10.1021/...
As the editorial highlights, understanding biological systems requires direct measurements at all molecular levels.
Unlocking the Potential of Single-Cell Omics
pubs.acs.org/doi/10.1021/...
April 5, 2025 at 12:45 PM
The JPR issue on Single-Cell Omics is out.
As the editorial highlights, understanding biological systems requires direct measurements at all molecular levels.
Unlocking the Potential of Single-Cell Omics
pubs.acs.org/doi/10.1021/...
As the editorial highlights, understanding biological systems requires direct measurements at all molecular levels.
Unlocking the Potential of Single-Cell Omics
pubs.acs.org/doi/10.1021/...
Thank you CBC for covering our latest study using
#proteomics and rapid patient derived models to inform patient care - out in EMBO Molecular Medicine.
A first in Canada step towards improved personalized #PrecisionMedicine
CBC: www.cbc.ca/player/play/...
Article: www.embopress.org/doi/full/10....
#proteomics and rapid patient derived models to inform patient care - out in EMBO Molecular Medicine.
A first in Canada step towards improved personalized #PrecisionMedicine
CBC: www.cbc.ca/player/play/...
Article: www.embopress.org/doi/full/10....
April 3, 2025 at 12:47 AM
Thank you CBC for covering our latest study using
#proteomics and rapid patient derived models to inform patient care - out in EMBO Molecular Medicine.
A first in Canada step towards improved personalized #PrecisionMedicine
CBC: www.cbc.ca/player/play/...
Article: www.embopress.org/doi/full/10....
#proteomics and rapid patient derived models to inform patient care - out in EMBO Molecular Medicine.
A first in Canada step towards improved personalized #PrecisionMedicine
CBC: www.cbc.ca/player/play/...
Article: www.embopress.org/doi/full/10....
Our first case-study using hashtag#proteomics and rapid patient derived models in parallel to genome sequencing to inform patient care now out in EMBO Molecular Medicine.
lnkd.in/gc3AKEfR
lnkd.in/gc3AKEfR
LinkedIn
This link will take you to a page that’s not on LinkedIn
lnkd.in
April 1, 2025 at 5:33 PM
Our first case-study using hashtag#proteomics and rapid patient derived models in parallel to genome sequencing to inform patient care now out in EMBO Molecular Medicine.
lnkd.in/gc3AKEfR
lnkd.in/gc3AKEfR
Classics. Quick reads that will get you off to a good start.
Three must read papers for PhD students. #scisky #PhD #science #research #academicsky
1. The importance of stupidity in scientific research
Open Access
journals.biologists.com/jcs/article/...
1. The importance of stupidity in scientific research
Open Access
journals.biologists.com/jcs/article/...
December 1, 2024 at 6:43 PM
Classics. Quick reads that will get you off to a good start.
Next batch has been added to the proteomics starter pack.
go.bsky.app/GYoxs2r
go.bsky.app/GYoxs2r
November 25, 2024 at 12:27 AM
Next batch has been added to the proteomics starter pack.
go.bsky.app/GYoxs2r
go.bsky.app/GYoxs2r
The growth of this community is amazing. I started a starter pack to bing the proteomics community together and accelerate this further
Proteomics - go.bsky.app/GYoxs2r
Please let me know if I missed you. I will curate this pack as new people gather under the blue sky
#proteomics #team-massspec
Proteomics - go.bsky.app/GYoxs2r
Please let me know if I missed you. I will curate this pack as new people gather under the blue sky
#proteomics #team-massspec
November 22, 2024 at 8:05 PM
The growth of this community is amazing. I started a starter pack to bing the proteomics community together and accelerate this further
Proteomics - go.bsky.app/GYoxs2r
Please let me know if I missed you. I will curate this pack as new people gather under the blue sky
#proteomics #team-massspec
Proteomics - go.bsky.app/GYoxs2r
Please let me know if I missed you. I will curate this pack as new people gather under the blue sky
#proteomics #team-massspec
It has been so much fun to run this. The science was outstanding and the connections that were made will be long lasting. We had it all - breakthrough science, bears guarding the pub and the first snow of the season.
Thank you all for coming! See you at HUPO/CNPN 2025 in Toronto.
Thank you all for coming! See you at HUPO/CNPN 2025 in Toronto.
Thanks to CNPN 2024 organizers, @philipplange.bsky.social and Mari De Marco, great sponsors, and all participants who made this conference happen🙌
November 22, 2024 at 5:21 AM
It has been so much fun to run this. The science was outstanding and the connections that were made will be long lasting. We had it all - breakthrough science, bears guarding the pub and the first snow of the season.
Thank you all for coming! See you at HUPO/CNPN 2025 in Toronto.
Thank you all for coming! See you at HUPO/CNPN 2025 in Toronto.
Reposted by Philipp Lange (he/him)
Ryan from our lab presenting his work @cnpn looking at yeast strains capable of producing more recombinant proteins. When we started doing #proteomics we actually found quite important differences between these strains
More here www.biorxiv.org/content/10.1...
More here www.biorxiv.org/content/10.1...
November 18, 2024 at 7:39 PM
Ryan from our lab presenting his work @cnpn looking at yeast strains capable of producing more recombinant proteins. When we started doing #proteomics we actually found quite important differences between these strains
More here www.biorxiv.org/content/10.1...
More here www.biorxiv.org/content/10.1...
Reposted by Philipp Lange (he/him)
Snowflakes & Proteomics: the 2024 CNPN Fairmont fairytale… once upon a time there was a tiny single cell (Ljijana Pasa-Tolic), a mutated proteome (Matthew Berg from the Villen lab) and a nasty protease (Olivier Julien)…
November 18, 2024 at 6:35 AM
Snowflakes & Proteomics: the 2024 CNPN Fairmont fairytale… once upon a time there was a tiny single cell (Ljijana Pasa-Tolic), a mutated proteome (Matthew Berg from the Villen lab) and a nasty protease (Olivier Julien)…
It is a pleasure to host this year's conference of the Canadian National Proteomics Network. Such a brilliant and smart crowd that has gathered in Whistler.
CNPN 2024 just kicked off by Dr. Mari Demarco and Dr. Philipp Lange in Whistler, BC🥳🙌😍🎉
Thanks so much to our sponsors, especially @Thermofisher
Thanks so much to our sponsors, especially @Thermofisher
November 18, 2024 at 5:14 PM
It is a pleasure to host this year's conference of the Canadian National Proteomics Network. Such a brilliant and smart crowd that has gathered in Whistler.
This captures our first evening of CNPN 2024 so well!
Snowflakes & Proteomics: the 2024 CNPN Fairmont fairytale… once upon a time there was a tiny single cell (Ljijana Pasa-Tolic), a mutated proteome (Matthew Berg from the Villen lab) and a nasty protease (Olivier Julien)…
November 18, 2024 at 5:12 PM
This captures our first evening of CNPN 2024 so well!
Reposted by Philipp Lange (he/him)
CNPN 2024 just kicked off by Dr. Mari Demarco and Dr. Philipp Lange in Whistler, BC🥳🙌😍🎉
Thanks so much to our sponsors, especially @Thermofisher
Thanks so much to our sponsors, especially @Thermofisher
November 18, 2024 at 1:55 AM
CNPN 2024 just kicked off by Dr. Mari Demarco and Dr. Philipp Lange in Whistler, BC🥳🙌😍🎉
Thanks so much to our sponsors, especially @Thermofisher
Thanks so much to our sponsors, especially @Thermofisher
Reposted by Philipp Lange (he/him)
Research Associate I/II, Proteomics – Vividion Therapeutics, Inc – San Diego, CA – San Diego Biotechnology Network sdbn.org/san-diego-b...
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#proteomics #prot-jobs
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#proteomics #prot-jobs
April 24, 2024 at 8:00 AM
Research Associate I/II, Proteomics – Vividion Therapeutics, Inc – San Diego, CA – San Diego Biotechnology Network sdbn.org/san-diego-b...
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#proteomics #prot-jobs
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#proteomics #prot-jobs
Budget day and A fantastic day for 🇨🇦 Canadian science! Finally students and postdocs get recognized for their outsized contributions to society and see big increases in fellowships. Great time to join a 🇨🇦 lab! Reach out.
April 17, 2024 at 2:15 AM
Budget day and A fantastic day for 🇨🇦 Canadian science! Finally students and postdocs get recognized for their outsized contributions to society and see big increases in fellowships. Great time to join a 🇨🇦 lab! Reach out.
@lkpino.bsky.social @talusbio.bsky.social kicking off the BC Proteomics & Metabolomics Network Symposium with a phenomenal keynote. Transcription factors, mass spec in drug development, startups, off target effects, … beautiful tour de force. #proteomics.sky
February 21, 2024 at 5:35 PM
@lkpino.bsky.social @talusbio.bsky.social kicking off the BC Proteomics & Metabolomics Network Symposium with a phenomenal keynote. Transcription factors, mass spec in drug development, startups, off target effects, … beautiful tour de force. #proteomics.sky
What are people's current preferred configurations for systems running Spectronaut or DIANN? Do both make use of GPUs?
#proteomics #TeamMassSpec
#proteomics #TeamMassSpec
February 8, 2024 at 1:23 AM
What are people's current preferred configurations for systems running Spectronaut or DIANN? Do both make use of GPUs?
#proteomics #TeamMassSpec
#proteomics #TeamMassSpec
Reposted by Philipp Lange (he/him)
POTRHList, why not! Thanks to @ucdproteomics.bsky.social and all the people who joined. Some random links to topics.
1/n
1/n
www.clubhouse.com/invite/1djuw... hey - you should join us Jan 31, 10:00 am for Proteomics Old-Time Radio Hour. Man why do they always use my pic and not you @benneely.com 🤣
Proteomics Old-Time Radio Hour - Clubhouse
Huuuge group voice notes with all of your friends
www.clubhouse.com
January 31, 2024 at 7:28 PM
POTRHList, why not! Thanks to @ucdproteomics.bsky.social and all the people who joined. Some random links to topics.
1/n
1/n
First timsTOF Ultra in Canada🇨🇦 installed (Dec 2023) @BC Children's & @ubcmedicine.bsky.social. We were busy with our first neuroblastoma cohort so forgot to share this exciting news here. Heartfelt thanks to our donors & BC Children's Hospital Foundation! #TeamMassSpec #Proteomics #Cancer
January 31, 2024 at 7:48 PM
First timsTOF Ultra in Canada🇨🇦 installed (Dec 2023) @BC Children's & @ubcmedicine.bsky.social. We were busy with our first neuroblastoma cohort so forgot to share this exciting news here. Heartfelt thanks to our donors & BC Children's Hospital Foundation! #TeamMassSpec #Proteomics #Cancer
Reposted by Philipp Lange (he/him)
I'm team-teaching with Brian Searle at the Ubuntu School in a couple weeks. We're putting together a whole new set of lectures and tutorials for data quality assessment of DIA and other chromatogram-based quantitative mass spec using the @benneely.com ABRF sPRG tribrid proteome as demo data
Second Ubuntu Proteomics Summer School | 5-9 feb, 2024 | Johannesburg, South Africa --- vbn.aau.dk/da/activi...
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#proteomics #prot-conf
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#proteomics #prot-conf
January 19, 2024 at 4:44 PM
I'm team-teaching with Brian Searle at the Ubuntu School in a couple weeks. We're putting together a whole new set of lectures and tutorials for data quality assessment of DIA and other chromatogram-based quantitative mass spec using the @benneely.com ABRF sPRG tribrid proteome as demo data
Reposted by Philipp Lange (he/him)
Excited to introduce this behemoth of a manuscript enabling the prediction of drug response in acute myeloid leukemia through integration of protein and gene measurements across hundreds of patient samples. #AML #drugresistance #machinelearning #proteomics
www.cell.com/cell-reports...
www.cell.com/cell-reports...
January 17, 2024 at 9:44 PM
Excited to introduce this behemoth of a manuscript enabling the prediction of drug response in acute myeloid leukemia through integration of protein and gene measurements across hundreds of patient samples. #AML #drugresistance #machinelearning #proteomics
www.cell.com/cell-reports...
www.cell.com/cell-reports...
Reposted by Philipp Lange (he/him)
Hey, science folks of Bluesky! Addgene has announced that it is fully committing to leaving X. They are taking a hit in their social media visibility to do this, but they have good reasons (blog.addgene.org/addgene-is-s...), as many of us do. Please give them a follow: @addgene.bsky.social
Addgene is Stopping Use of X (formerly Twitter)
Addgene will no longer be posting, monitoring, or responding to posts on X. You can find us as @addgene.bsky.social on Bluesky or as @addgene on Instagram, TikTok, Facebook, and LinkedIn.
blog.addgene.org
January 11, 2024 at 2:48 PM
Hey, science folks of Bluesky! Addgene has announced that it is fully committing to leaving X. They are taking a hit in their social media visibility to do this, but they have good reasons (blog.addgene.org/addgene-is-s...), as many of us do. Please give them a follow: @addgene.bsky.social
Reposted by Philipp Lange (he/him)
We've experienced this only when there were selected deodorants or antiperspirants worn in the lab. I can assure you that Old Spice is a nightmare in an MS lab. We spent months tracking it down in the past. Here's the paper that gave us the idea to consider it. pubs.acs.org/doi/10.1021/...
24-Hour Lock Mass Protection
The positive role and application of highly accurate mass measurements in proteomics is well documented. The new generation of hybrid FTMS and Q-TOF instruments, including the LTQ-Orbitrap (OT), is re...
pubs.acs.org
January 8, 2024 at 2:06 PM
We've experienced this only when there were selected deodorants or antiperspirants worn in the lab. I can assure you that Old Spice is a nightmare in an MS lab. We spent months tracking it down in the past. Here's the paper that gave us the idea to consider it. pubs.acs.org/doi/10.1021/...
Reposted by Philipp Lange (he/him)
Seeing really high polysiloxane background with IonOpticks TS and low flow/Whisper methods. Nanospray flex source. Any similar experience? #MassSOS
January 5, 2024 at 9:09 PM
Seeing really high polysiloxane background with IonOpticks TS and low flow/Whisper methods. Nanospray flex source. Any similar experience? #MassSOS
Reposted by Philipp Lange (he/him)
News in Proteomics Research blog post | Single cell epigenetics/epiproteomics by mass spectrometry time! proteomicsnews.blogs...
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#proteomics #prot-other
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#proteomics #prot-other
January 7, 2024 at 4:00 PM
News in Proteomics Research blog post | Single cell epigenetics/epiproteomics by mass spectrometry time! proteomicsnews.blogs...
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#proteomics #prot-other
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#proteomics #prot-other